PPM1G and MSL1

Number of citations of the paper that reports this interaction (PubMedID 19650074)
0

Data Source:
BioGRID (two hybrid)

		PPM1G	MSL1
Description		protein phosphatase, Mg2+/Mn2+ dependent 1G	MSL complex subunit 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Membrane	Nucleus Nucleoplasm Nuclear Speck MSL Complex
	Molecular Function	Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Binding Hydrolase Activity Cation Binding Metal Ion Binding	Protein Binding Protein-macromolecule Adaptor Activity
	Biological Process	Protein Dephosphorylation Signal Transduction Peptidyl-threonine Dephosphorylation Regulation Of Cell Cycle	Chromatin Organization Chromatin Remodeling Positive Regulation Of DNA-templated Transcription
Pathways			HATs acetylate histones
Drugs
Diseases
GWAS		Bone mineral density (total hip) ( 29883787) Creatinine levels ( 31015462) Crohn's disease ( 28067908) Hypertriglyceridemia ( 23505323) Inflammatory bowel disease ( 28067908) Non-oily fish consumption ( 32066663) Takayasu arteritis ( 25604533) Triglyceride levels ( 31928498)	Asthma ( 31619474)
Interacting Genes		11 interacting genes: FBXO38 GRIA3 H3-4 HEXIM1 LRPAP1 MSL1 MTNR1B RN7SK RPS6KA1 TERF1 TERF2	17 interacting genes: CRKL FCHSD2 H2BC21 HORMAD1 HSPB1 KPNB1 MORF4L1 MRGBP NUPR1 PAF1 PPM1G RAN RNF20 RNF40 SMARCC1 SNW1 UBE2D3
Entrez ID		5496	339287
HPRD ID		09237	19425
Ensembl ID		ENSG00000115241	ENSG00000188895
Uniprot IDs		O15355 Q6IAU5	B3KWR7 J3KSZ8 J3QQY0 Q68DK7
PDB IDs			4B7Y 4B86 4DNC
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication 7SK SnRNP Shelterin Complex Telomerase Activity Nuclear Telomere Cap Complex Telomeric D-loop Disassembly Double-stranded Telomeric DNA Binding G-rich Strand Telomeric DNA Binding Telomeric Loop Disassembly Telomere Capping Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Transcription Elongation By RNA Polymerase II RNA-templated DNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription, Elongation Telomeric DNA Binding Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Biosynthetic Process Chromosome, Telomeric Region Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Gamma-glutamyl Carboxylase Activity Negative Regulation Of Establishment Of Protein Localization To Telomere Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly Telomere Cap Complex Negative Regulation Of Telomere Maintenance Via Recombination Axonal Transport Of Messenger Ribonucleoprotein Complex Negative Regulation Of Telomere Single Strand Break Repair Vitamin Binding Negative Regulation Of Bone Development Chemical Synaptic Transmission Positive Regulation Of Telomere Maintenance Negative Regulation Of Chromosome Organization Telomeric Loop Formation Negative Regulation Of DNA Recombination At Telomere Trans-synaptic Signaling Synaptic Signaling Regulation Of DNA Biosynthetic Process Amyloid-beta Binding DNA Biosynthetic Process Regulation Of Transcription Elongation By RNA Polymerase II Negative Regulation Of Testosterone Biosynthetic Process Rough Endoplasmic Reticulum Lumen Negative Regulation Of T-circle Formation Telomere Maintenance Positive Regulation Of Chromosome Organization Regulation Of DNA-templated Transcription Elongation	Nucleoplasm Regulation Of Cell Cycle Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription RNA Import Into Nucleus Chromatin Binding HULC Complex Positive Regulation Of RNA Metabolic Process Nucleus Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Importin-alpha Family Protein Binding Positive Regulation Of Biosynthetic Process Chromatin Organization Positive Regulation Of Double-strand Break Repair Transcription Coactivator Activity Retinoic Acid Receptor Signaling Pathway Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Nucleosome Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process NuA4 Histone Acetyltransferase Complex Positive Regulation Of DNA Repair Regulation Of Double-strand Break Repair Regulation Of RNA Metabolic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Metabolic Process Protein Localization To Nucleus Fibroblast Proliferation Reproductive Structure Development Negative Regulation Of Protein Kinase C Signaling Regulation Of Nucleobase-containing Compound Metabolic Process Stereocilium Shaft Positive Regulation Of Double-strand Break Repair Via Homologous Recombination H4/H2A Histone Acetyltransferase Complex Histone H2B C-terminal K Residue Ubiquitin Ligase Activity Regulation Of Macromolecule Metabolic Process Male Germ Cell Nucleus Developmental Process Involved In Reproduction Regulation Of DNA Repair Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Cellular Response To Stress Helper T Cell Diapedesis RNA Nuclear Export Complex SnRNA Import Into Nucleus Pre-miRNA Export From Nucleus Ubiquitin-protein Transferase Activity Regulation Of Primary Metabolic Process
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