Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
COMMD8 and AKR1C1
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
COMMD8
AKR1C1
Gene Name
COMM domain containing 8
aldo-keto reductase family 1, member C1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytosol
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
Alditol:NADP+ 1-oxidoreductase Activity
Aldo-keto Reductase (NADP) Activity
Oxidoreductase Activity, Acting On NAD(P)H, Quinone Or Similar Compound As Acceptor
Phenanthrene 9,10-monooxygenase Activity
Carboxylic Acid Binding
Bile Acid Binding
17-alpha,20-alpha-dihydroxypregn-4-en-3-one Dehydrogenase Activity
Androsterone Dehydrogenase (B-specific) Activity
Ketosteroid Monooxygenase Activity
Trans-1,2-dihydrobenzene-1,2-diol Dehydrogenase Activity
Indanol Dehydrogenase Activity
Biological Process
Retinoid Metabolic Process
Xenobiotic Metabolic Process
Digestion
Phototransduction, Visible Light
Bile Acid Metabolic Process
Bile Acid And Bile Salt Transport
Intestinal Cholesterol Absorption
Epithelial Cell Differentiation
Progesterone Metabolic Process
Retinal Metabolic Process
Cholesterol Homeostasis
Daunorubicin Metabolic Process
Doxorubicin Metabolic Process
Response To Organophosphorus
Protein Homooligomerization
Oxidation-reduction Process
Cellular Response To Jasmonic Acid Stimulus
Pathways
Bile acid and bile salt metabolism
Synthesis of bile acids and bile salts via 24-hydroxycholesterol
Synthesis of bile acids and bile salts via 27-hydroxycholesterol
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
Metabolism of lipids and lipoproteins
Visual phototransduction
Diseases associated with visual transduction
Synthesis of bile acids and bile salts
Retinoid metabolism and transport
Drugs
NADH
Salicyclic acid
Acetylsalicylic acid
2\'-Monophosphoadenosine 5\'-Diphosphoribose
2-HYDROXY-3,5-DIIODOBENZOIC ACID
(10ALPHA,13ALPHA,14BETA,17ALPHA)-17-HYDROXYANDROST-4-EN-3-ONE
4-[(1R,2S)-1-ethyl-2-(4-hydroxyphenyl)butyl]phenol
Diseases
GWAS
Economic and political preferences (immigration/crime) (
22566634
)
Protein-Protein Interactions
5 interactors:
AKR1C1
COMMD1
COMMD3
NDUFA4L2
TMX2
3 interactors:
COMMD8
MAPK3
PTPN3
Entrez ID
54951
1645
HPRD ID
13086
07194
Ensembl ID
ENSG00000169019
Uniprot IDs
Q9NX08
Q04828
PDB IDs
1MRQ
3C3U
3GUG
3NTY
Enriched GO Terms of Interacting Partners
?
Homeostatic Process
Cellular Response To Jasmonic Acid Stimulus
Negative Regulation Of Sodium Ion Transmembrane Transport
Plasma Membrane To Endosome Transport
Daunorubicin Metabolic Process
Doxorubicin Metabolic Process
Intestinal Cholesterol Absorption
Negative Regulation Of Protein Localization To Cell Surface
Negative Regulation Of Sodium Ion Transport
Lipid Digestion
Retinal Metabolic Process
Glycoside Metabolic Process
Regulation Of Protein Localization To Cell Surface
Progesterone Metabolic Process
Copper Ion Homeostasis
Intestinal Absorption
C21-steroid Hormone Metabolic Process
Chemical Homeostasis
Bile Acid And Bile Salt Transport
Golgi To Plasma Membrane Transport
Regulation Of Sodium Ion Transmembrane Transport
Bile Acid Metabolic Process
Quinone Metabolic Process
Negative Regulation Of Ion Transmembrane Transport
Negative Regulation Of Transmembrane Transport
Negative Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Sodium Ion Transport
Sterol Transport
Cholesterol Transport
Phototransduction, Visible Light
Cellular Aldehyde Metabolic Process
Cholesterol Homeostasis
Retinoid Metabolic Process
Cellular Ketone Metabolic Process
Sterol Homeostasis
Diterpenoid Metabolic Process
Post-Golgi Vesicle-mediated Transport
Detection Of Visible Light
Phototransduction
Negative Regulation Of Ion Transport
Detection Of Light Stimulus
Lipid Homeostasis
Digestion
Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Isoprenoid Metabolic Process
Cell Redox Homeostasis
Negative Regulation Of Apolipoprotein Binding
Regulation Of Golgi Inheritance
Liver Regeneration
Caveolin-mediated Endocytosis
Positive Regulation Of Histone Phosphorylation
Regulation Of Membrane Depolarization During Action Potential
Negative Regulation Of Membrane Protein Ectodomain Proteolysis
Regulation Of Golgi Organization
Regulation Of Early Endosome To Late Endosome Transport
DNA Damage Induced Protein Phosphorylation
Interleukin-1-mediated Signaling Pathway
Positive Regulation Of Histone Acetylation
JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway
Positive Regulation Of Peptidyl-lysine Acetylation
Growth Hormone Receptor Signaling Pathway
Positive Regulation Of Protein Acetylation
Cellular Response To Growth Hormone Stimulus
Transcription Initiation From RNA Polymerase I Promoter
Regulation Of Sodium Ion Transmembrane Transporter Activity
Response To Epidermal Growth Factor
Regulation Of Cellular Response To Heat
Transcription From RNA Polymerase I Promoter
Regulation Of Membrane Depolarization
Lipopolysaccharide-mediated Signaling Pathway
Regulation Of Sodium Ion Transmembrane Transport
Peptidyl-tyrosine Autophosphorylation
Response To Growth Hormone
Response To Exogenous DsRNA
Regulation Of Histone Acetylation
Negative Regulation Of Protein Binding
Toll-like Receptor 5 Signaling Pathway
JAK-STAT Cascade
Toll-like Receptor 10 Signaling Pathway
Cellular Response To Interleukin-1
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Toll-like Receptor 2 Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
Cellular Response To Heat
Activation Of MAPKK Activity
Regulation Of Sodium Ion Transport
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Response To DsRNA
MyD88-dependent Toll-like Receptor Signaling Pathway
Cellular Response To Mechanical Stimulus
Positive Regulation Of Histone Modification
Organ Regeneration
BMP Signaling Pathway
Tagcloud
?
11beta
9alpha
abcc4
catalyze
diseased
endometriosis
endometriotic
endometrium
gynecological
hieec
hiesc
hpgd
hpgds
infertility
peritoneal
pgd2
pgf2alpha
pgh2
pla2g2a
pla2g4a
provokes
ptgds
ptgfr
ptgs2
reaches
slco2a
synthases
Tagcloud (Difference)
?
11beta
9alpha
abcc4
catalyze
diseased
endometriosis
endometriotic
endometrium
gynecological
hieec
hiesc
hpgd
hpgds
infertility
peritoneal
pgd2
pgf2alpha
pgh2
pla2g2a
pla2g4a
provokes
ptgds
ptgfr
ptgs2
reaches
slco2a
synthases
Tagcloud (Intersection)
?