COMMD8 and NDUFA4L2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		COMMD8	NDUFA4L2
Gene Name		COMM domain containing 8	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component
	Molecular Function	Protein Binding
	Biological Process
Pathways
Drugs			NADH
Diseases
GWAS
Protein-Protein Interactions		5 interactors: AKR1C1 COMMD1 COMMD3 NDUFA4L2 TMX2	13 interactors: ANXA9 C14orf1 C6orf62 COMMD8 DYNLL1 EIF3C KAT5 KCNA4 LUC7L2 PARK2 QTRT1 SLC35F6 UBR1
Entrez ID		54951	56901
HPRD ID		13086	14249
Ensembl ID		ENSG00000169019	ENSG00000185633
Uniprot IDs		Q9NX08	Q9NRX3
PDB IDs
Enriched GO Terms of Interacting Partners?		Homeostatic Process Cellular Response To Jasmonic Acid Stimulus Negative Regulation Of Sodium Ion Transmembrane Transport Plasma Membrane To Endosome Transport Daunorubicin Metabolic Process Doxorubicin Metabolic Process Intestinal Cholesterol Absorption Negative Regulation Of Protein Localization To Cell Surface Negative Regulation Of Sodium Ion Transport Lipid Digestion Retinal Metabolic Process Glycoside Metabolic Process Regulation Of Protein Localization To Cell Surface Progesterone Metabolic Process Copper Ion Homeostasis Intestinal Absorption C21-steroid Hormone Metabolic Process Chemical Homeostasis Bile Acid And Bile Salt Transport Golgi To Plasma Membrane Transport Regulation Of Sodium Ion Transmembrane Transport Bile Acid Metabolic Process Quinone Metabolic Process Negative Regulation Of Ion Transmembrane Transport Negative Regulation Of Transmembrane Transport Negative Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Sodium Ion Transport Sterol Transport Cholesterol Transport Phototransduction, Visible Light Cellular Aldehyde Metabolic Process Cholesterol Homeostasis Retinoid Metabolic Process Cellular Ketone Metabolic Process Sterol Homeostasis Diterpenoid Metabolic Process Post-Golgi Vesicle-mediated Transport Detection Of Visible Light Phototransduction Negative Regulation Of Ion Transport Detection Of Light Stimulus Lipid Homeostasis Digestion Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Isoprenoid Metabolic Process Cell Redox Homeostasis	Regulation Of Mitochondrion Organization Negative Regulation Of Mitochondrion Organization Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Mitochondrial Fusion Positive Regulation Of Protein Linear Polyubiquitination Cellular Response To Leucine Dopamine Uptake Involved In Synaptic Transmission Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Dopamine Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Queuosine Biosynthetic Process Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Manganese Ion Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Protein K27-linked Ubiquitination Protein K29-linked Ubiquitination Negative Regulation Of Mitochondrial Fusion Cellular Protein Catabolic Process Synaptic Transmission Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Mitochondrial Fusion Protein Catabolic Process Ribonucleoprotein Complex Assembly Negative Regulation Of Glucokinase Activity Neuron Cellular Homeostasis Response To Leucine Positive Regulation Of Oxidative Stress-induced Cell Death Protein K6-linked Ubiquitination Negative Regulation Of Oxidative Stress-induced Neuron Death Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Fission Regulation Of Mitochondrion Degradation Dopamine Transport Aggresome Assembly Regulation Of Mitochondrial Fission Neurotransmitter Uptake Norepinephrine Metabolic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Negative Regulation Of Actin Filament Bundle Assembly Synaptic Transmission, Dopaminergic Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Apoptotic Signaling Pathway Proteasomal Protein Catabolic Process Cellular Macromolecule Catabolic Process
Tagcloud ?			apoeepsilon4 astrocyte astrocytes billion c3 capture carriers cd74 cingulate clarified clu coexpression contributions decades deficits differentially fastkd2 measureable microdissected pc posterior precuneus publicly reads resource storage transcriptome trmt61b weighted
Tagcloud (Difference) ?			apoeepsilon4 astrocyte astrocytes billion c3 capture carriers cd74 cingulate clarified clu coexpression contributions decades deficits differentially fastkd2 measureable microdissected pc posterior precuneus publicly reads resource storage transcriptome trmt61b weighted
Tagcloud (Intersection) ?