PIGG and PIGF

Number of citations: 0 (PubMedID 15632136)
Data Source: HPRD (in vivo, in vitro)

		PIGG	PIGF
Name		phosphatidylinositol glycan anchor biosynthesis class G (EMM blood group)	phosphatidylinositol glycan anchor biosynthesis class F
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Transferase Activity Phosphotransferase Activity, For Other Substituted Phosphate Groups CP2 Mannose-ethanolamine Phosphotransferase Activity Mannose-ethanolamine Phosphotransferase Activity	Ethanolaminephosphotransferase Activity Protein Binding
	Biological Process	GPI Anchor Biosynthetic Process	GPI Anchor Biosynthetic Process
Pathways		Synthesis of glycosylphosphatidylinositol (GPI)	Synthesis of glycosylphosphatidylinositol (GPI) Synthesis of glycosylphosphatidylinositol (GPI)
GWAS		Initial alcohol sensitivity ( 30276832 )	Brain morphology (min-P) ( 32665545 ) Brain morphology (MOSTest) ( 32665545 ) Cortical surface area (min-P) ( 32665545 ) Cortical surface area (MOSTest) ( 32665545 ) Cortical thickness (MOSTest) ( 32665545 ) Height ( 20966902 ) Subcortical volume (min-P) ( 32665545 ) Subcortical volume (MOSTest) ( 32665545 )
Interacting Genes		4 interacting genes: APP DRD2 GLP1R PIGF	10 interacting genes: AQP6 GPR152 LYVE1 MANBAL PIGG PIGO TIMMDC1 TMEM130 TMEM14B TMEM86B
Entrez ID		54872	5281
HPRD ID		07890	02539
Ensembl ID		ENSG00000174227	ENSG00000151665
Uniprot IDs		D6RFE8 E7EM50 E7EWV1 Q5H8A4 Q8NCI4	H7C392 Q07326 Q6IB04
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Blood Circulation Learning Or Memory Positive Regulation Of Long-term Synaptic Potentiation Regulation Of Neurotransmitter Uptake Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Receptor Internalization Cognition Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Long-term Synaptic Potentiation Negative Regulation Of Blood Pressure Visual Learning Positive Regulation Of Receptor-mediated Endocytosis Regulation Of Neuronal Synaptic Plasticity Visual Behavior Regulation Of Multicellular Organism Growth Regulation Of Receptor Internalization Adult Locomotory Behavior Regulation Of System Process Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Amyloid-beta Complex Growth Cone Lamellipodium Associative Learning Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Glucagon-like Peptide 1 Receptor Activity Regulation Of Receptor-mediated Endocytosis Memory Acetylcholine Receptor Activator Activity PTB Domain Binding Regulation Of G Protein-coupled Receptor Signaling Pathway Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Cellular Response To Oxygen-containing Compound Endosome To Plasma Membrane Transport Vesicle Adult Behavior Positive Regulation Of Endothelin Production Positive Regulation Of Endocytosis Growth Cone Filopodium Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Synaptic Transmission Learning Lipoprotein Particle Perikaryon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Dendritic Spine	Mannose-ethanolamine Phosphotransferase Activity Phosphotransferase Activity, For Other Substituted Phosphate Groups Membrane GPI Anchor Metabolic Process GPI Anchor Biosynthetic Process Glycerophospholipid Metabolic Process Nitrate Transmembrane Transporter Activity Glycolipid Biosynthetic Process Glycerolipid Metabolic Process CP2 Mannose-ethanolamine Phosphotransferase Activity D-lysine 5,6-aminomutase Activity Phospholipid Metabolic Process PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Ether Hydrolase Activity Alkenylglycerophosphocholine Hydrolase Activity Glycolipid Metabolic Process Phosphatidylinositol Biosynthetic Process Phosphatidylinositol Metabolic Process Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Glycerophospholipid Biosynthetic Process Monoatomic Anion Channel Activity Renal Water Transport Ammonium Channel Activity Mitochondrial Membrane Membrane Lipid Metabolic Process Ammonium Transmembrane Transport Phospholipid Biosynthetic Process Hyaluronan Catabolic Process Water Channel Activity Phosphatidylcholine Acyl-chain Remodeling Carbon Dioxide Transport Carbohydrate Derivative Metabolic Process Transferase Activity, Transferring Phosphorus-containing Groups Positive Regulation Of Cellular Extravasation