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PIGF and TMEM130
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
PIGF
TMEM130
Description
phosphatidylinositol glycan anchor biosynthesis class F
transmembrane protein 130
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Membrane
Golgi Membrane
Golgi Apparatus
Plasma Membrane
Membrane
Molecular Function
Ethanolaminephosphotransferase Activity
Protein Binding
Protein Binding
Biological Process
GPI Anchor Biosynthetic Process
Pathways
Synthesis of glycosylphosphatidylinositol (GPI)
Synthesis of glycosylphosphatidylinositol (GPI)
Drugs
Diseases
GWAS
Brain morphology (min-P) (
32665545
)
Brain morphology (MOSTest) (
32665545
)
Cortical surface area (min-P) (
32665545
)
Cortical surface area (MOSTest) (
32665545
)
Cortical thickness (MOSTest) (
32665545
)
Height (
20966902
)
Subcortical volume (min-P) (
32665545
)
Subcortical volume (MOSTest) (
32665545
)
Decreased low contrast letter acuity in multiple sclerosis (
31289819
)
Interacting Genes
10 interacting genes:
AQP6
GPR152
LYVE1
MANBAL
PIGG
PIGO
TIMMDC1
TMEM130
TMEM14B
TMEM86B
10 interacting genes:
GRM2
NKG7
OLFM4
PIGF
SLC2A5
SLC35B4
SLC61A1
TMEM100
TSPAN2
YIPF6
Entrez ID
5281
222865
HPRD ID
02539
13226
Ensembl ID
ENSG00000151665
ENSG00000166448
Uniprot IDs
H7C392
Q07326
Q6IB04
Q8N3G9
PDB IDs
Enriched GO Terms of Interacting Partners
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Mannose-ethanolamine Phosphotransferase Activity
Phosphotransferase Activity, For Other Substituted Phosphate Groups
Membrane
GPI Anchor Metabolic Process
GPI Anchor Biosynthetic Process
Glycerophospholipid Metabolic Process
Nitrate Transmembrane Transporter Activity
Glycolipid Biosynthetic Process
Glycerolipid Metabolic Process
CP2 Mannose-ethanolamine Phosphotransferase Activity
D-lysine 5,6-aminomutase Activity
Phospholipid Metabolic Process
PH-gated Chloride Channel Activity
Nitrate Transmembrane Transport
Ether Hydrolase Activity
Alkenylglycerophosphocholine Hydrolase Activity
Glycolipid Metabolic Process
Phosphatidylinositol Biosynthetic Process
Phosphatidylinositol Metabolic Process
Carbon Dioxide Transmembrane Transporter Activity
Carbon Dioxide Transmembrane Transport
Glycerophospholipid Biosynthetic Process
Monoatomic Anion Channel Activity
Renal Water Transport
Ammonium Channel Activity
Mitochondrial Membrane
Membrane Lipid Metabolic Process
Ammonium Transmembrane Transport
Phospholipid Biosynthetic Process
Hyaluronan Catabolic Process
Water Channel Activity
Phosphatidylcholine Acyl-chain Remodeling
Carbon Dioxide Transport
Carbohydrate Derivative Metabolic Process
Transferase Activity, Transferring Phosphorus-containing Groups
Positive Regulation Of Cellular Extravasation
Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target
Fructose Import Across Plasma Membrane
UDP-xylose Transmembrane Transport
UDP-xylose Transmembrane Transporter Activity
Molybdate Ion Transmembrane Transporter Activity
Molybdate Ion Transport
Organic Anion Transport
Group II Metabotropic Glutamate Receptor Activity
Membrane
Ethanolaminephosphotransferase Activity
Microglia Development
UDP-N-acetylglucosamine Transmembrane Transporter Activity
UDP-N-acetylglucosamine Transmembrane Transport
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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