CKMT1A and ASB9

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology)

		CKMT1A	ASB9
Description		creatine kinase, mitochondrial 1A	ankyrin repeat and SOCS box containing 9
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane	Mitochondrion Cytosol Cul5-RING Ubiquitin Ligase Complex
	Molecular Function	Nucleotide Binding Catalytic Activity Creatine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Transferase Activity, Transferring Phosphorus-containing Groups	Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Phosphocreatine Biosynthetic Process	Protein Ubiquitination Intracellular Signal Transduction Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Catabolic Process
Pathways		Creatine metabolism	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs		Creatine Phosphocreatine
Diseases
GWAS		Diastolic blood pressure ( 27841878)	Metabolite levels ( 23823483)
Interacting Genes		10 interacting genes: ASB9 CTNNA3 HPCA NUTF2 OCM OGT PPP1R16A PSMC3 RXRG VDAC1	11 interacting genes: ACTN3 ASB13 CKB CKMT1A CKMT1B EXOSC1 HIF1AN LCK PLCG2 RELA UBE2D1
Entrez ID		548596	140462
HPRD ID		18683	06452
Ensembl ID		ENSG00000223572	ENSG00000102048
Uniprot IDs		P12532	A0A024RBW7 Q96DX5
PDB IDs		1QK1 9B04 9B05 9B0T 9B0U 9B14 9B16	3D9H 3ZKJ 3ZNG 6V9H
Enriched GO Terms of Interacting Partners?			Phosphocreatine Biosynthetic Process Creatine Kinase Activity Transferase Activity, Transferring Phosphorus-containing Groups Ankyrin Repeat Binding Positive Regulation Of T Cell Receptor Signaling Pathway Modified Amino Acid Metabolic Process Positive Regulation Of Antigen Receptor-mediated Signaling Pathway NF-kappaB Binding Regulation Of Calcineurin-mediated Signaling Regulation Of Calcineurin-NFAT Signaling Cascade Organophosphate Biosynthetic Process Positive Regulation Of Interleukin-12 Production Kinase Activity Phosphotyrosine Residue Binding Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of T Cell Receptor Signaling Pathway Toll-like Receptor Signaling Pathway Positive Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Release Of Sequestered Calcium Ion Into Cytosol Fc Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway B Cell Receptor Signaling Pathway Negative Regulation Of Sequestering Of Calcium Ion [protein]-asparagine 3-dioxygenase Activity Regulation Of Interleukin-12 Production Cytosol Platelet Activation Catalytic Activity Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Phosphate-containing Compound Metabolic Process Regulation Of The Force Of Skeletal Muscle Contraction Positive Regulation Of Fast-twitch Skeletal Muscle Fiber Contraction Futile Creatine Cycle ATP Binding Immune Response-activating Signaling Pathway NF-kappaB P50/p65 Complex Peptidyl-aspartic Acid 3-dioxygenase Activity Calcium Ion Transmembrane Import Into Cytosol Regulation Of Calcium-mediated Signaling Positive Regulation Of Cell Differentiation Positive Regulation Of Interleukin-6 Production Positive Regulation Of Bone Mineralization Involved In Bone Maturation Inositol Trisphosphate Biosynthetic Process Positive Regulation Of Schwann Cell Differentiation Response To Cobalamin Peptidyl-histidine Dioxygenase Activity Organophosphate Metabolic Process Immune Response-regulating Signaling Pathway Activation Of Immune Response T Cell Receptor Signaling Pathway
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