ESRP1 and PRR20A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ESRP1	PRR20A
Description		epithelial splicing regulatory protein 1	proline rich 20A
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Body Ribonucleoprotein Complex
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding
	Biological Process	MRNA Processing RNA Splicing Regulation Of Inner Ear Auditory Receptor Cell Fate Specification Regulation Of RNA Splicing
Pathways		Signaling by BRAF and RAF1 fusions FGFR2 alternative splicing
Drugs
Diseases
GWAS		Abstraction and mental flexibility ( 31596458) Urate levels ( 31578528)	Cerebrospinal fluid t-tau:AB1-42 ratio ( 30153862) Left ventricular end-diastolic volume (MTAG) ( 33495596) Left ventricular end-systolic volume (MTAG) ( 33495596) Left ventricular mass (MTAG) ( 33495596) Systolic blood pressure ( 30224653) Total cholesterol levels ( 33339817)
Interacting Genes		49 interacting genes: ALG13 ARID5A ATXN1 DAZAP2 H19 KLHDC7B KRTAP19-5 MED25 MIR106A MIR106B MIR128-2 MIR138-1 MIR138-2 MIR141 MIR155 MIR15B MIR19B1 MIR19B2 MIR200A MIR200C MIR20B MIR21 MIR222 MIR25 MIR29C MIR34A MIR34B MIR363 MIR7-1 MIR9-1 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7F2 MIRLET7G MIRLET7I MRPS24 OXER1 PRR20A PRR20B PRR20C PRR20D PRR20E RBPMS2 ZC3H10	95 interacting genes: ABI2 ANKHD1 ARID5A ATXN1 BANP BEND2 BHLHE40 BICRAL C10orf55 C1orf94 C3orf36 CABP2 CCNK CDC37 CELF4 DAB1 DAZAP2 DMRT3 DVL3 EIF4ENIF1 ESRP1 FAM168A FAM222B FAM9A FOXH1 FOXP3 GATA2 GLIS2 GTF2A1 HIVEP1 HLX HYPK KRTAP19-1 KRTAP19-5 LASP1 MAGED1 MBNL3 NAA38 NCK2 NEDD9 NOTCH3 NTAQ1 OXER1 PATZ1 PHF1 PITX1 POGZ POU6F2 PRR20B PRR20C PRR20D PRR20E PRR34 PRR35 PTTG2 RBFOX1 RBM10 RBM23 RBM42 RBPMS RBPMS2 RHOXF2 RIPPLY1 RNF4 ROR2 SAMD11 SELENOV SH3RF1 SMAP1 SNRPB SNRPC SOX5 SP4 SRPK2 TBX3 TBX6 TCF7L2 TFG THAP1 TIAL1 TLX3 TOLLIP TPRX1 TRIM35 VAC14 VENTX VEZF1 VPS37C YPEL3 ZBTB32 ZC3H10 ZCCHC14 ZNF385C ZNF488 ZNF683
Entrez ID		54845	122183
HPRD ID		07881	13445
Ensembl ID		ENSG00000104413	ENSG00000204919
Uniprot IDs		A0A2U3TZN9 Q6NXG1	P86478 P86479 P86480 P86481 P86496
PDB IDs		2DHA 2RVJ 7VKI 7VKJ 7WRN
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing RISC Complex Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MiRNA-mediated Gene Silencing By Inhibition Of Translation Extracellular Vesicle MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MRNA Destabilization Negative Regulation Of Translation RNA Destabilization Positive Regulation Of MRNA Catabolic Process Regulation Of MRNA Stability Positive Regulation Of MRNA Metabolic Process Regulation Of RNA Stability Regulation Of MRNA Metabolic Process Regulation Of Vascular Endothelial Cell Proliferation Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Translation Negative Regulation Of Vascular Endothelial Cell Proliferation Negative Regulation Of Cytokine Production Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Negative Regulation Of Endothelial Cell Proliferation Regulation Of Endothelial Cell Proliferation Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Macromolecule Metabolic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Endothelial Cell Migration Regulation Of Angiogenesis Negative Regulation Of Cell Migration Regulation Of Vasculature Development Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Cell Motility Negative Regulation Of Signal Transduction Negative Regulation Of Locomotion Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Protein Metabolic Process Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis	Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Transcription By RNA Polymerase II Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression DNA Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Splicing Regulation Of Macromolecule Metabolic Process Chromatin Protein Binding Negative Regulation Of RNA Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Metabolic Process Positive Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Processing Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Nucleic Acid Binding Positive Regulation Of Biosynthetic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of Metabolic Process Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Regulation Of MRNA Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Activity Sequence-specific Double-stranded DNA Binding Negative Regulation Of Biosynthetic Process RNA Splicing Sequence-specific DNA Binding Cell Fate Commitment Nucleoplasm MRNA Binding Myoblast Fate Commitment Regulation Of Neuron Differentiation Regulation Of Developmental Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding
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