ESRP1 and KLHDC7B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ESRP1	KLHDC7B
Description		epithelial splicing regulatory protein 1	kelch domain containing 7B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Body Ribonucleoprotein Complex
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding	Protein Binding
	Biological Process	MRNA Processing RNA Splicing Regulation Of Inner Ear Auditory Receptor Cell Fate Specification Regulation Of RNA Splicing
Pathways		Signaling by BRAF and RAF1 fusions FGFR2 alternative splicing
Drugs
Diseases
GWAS		Abstraction and mental flexibility ( 31596458) Urate levels ( 31578528)	Age-related hearing impairment ( 34108613) Mean corpuscular hemoglobin ( 20139978) Monocyte count ( 32888494) Red blood cell count ( 29403010) Serum metabolite levels ( 33031748)
Interacting Genes		49 interacting genes: ALG13 ARID5A ATXN1 DAZAP2 H19 KLHDC7B KRTAP19-5 MED25 MIR106A MIR106B MIR128-2 MIR138-1 MIR138-2 MIR141 MIR155 MIR15B MIR19B1 MIR19B2 MIR200A MIR200C MIR20B MIR21 MIR222 MIR25 MIR29C MIR34A MIR34B MIR363 MIR7-1 MIR9-1 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7F2 MIRLET7G MIRLET7I MRPS24 OXER1 PRR20A PRR20B PRR20C PRR20D PRR20E RBPMS2 ZC3H10	25 interacting genes: A1CF BHLHE40 CFTR DTX2 ESRP1 FNDC3B HNRNPUL1 LIMS3 LIMS4 MAPRE3 NFYC PATZ1 PHC2 POGZ QRICH1 RBPMS RBPMS2 RHOXF2 SMUG1 SPMIP9 TBX6 TLE5 TP53BP1 WWOX ZC3H10
Entrez ID		54845	113730
HPRD ID		07881	14453
Ensembl ID		ENSG00000104413	ENSG00000130487
Uniprot IDs		A0A2U3TZN9 Q6NXG1	A0A3B3ISF6 Q96G42
PDB IDs		2DHA 2RVJ 7VKI 7VKJ 7WRN
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing RISC Complex Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MiRNA-mediated Gene Silencing By Inhibition Of Translation Extracellular Vesicle MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MRNA Destabilization Negative Regulation Of Translation RNA Destabilization Positive Regulation Of MRNA Catabolic Process Regulation Of MRNA Stability Positive Regulation Of MRNA Metabolic Process Regulation Of RNA Stability Regulation Of MRNA Metabolic Process Regulation Of Vascular Endothelial Cell Proliferation Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Translation Negative Regulation Of Vascular Endothelial Cell Proliferation Negative Regulation Of Cytokine Production Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Negative Regulation Of Endothelial Cell Proliferation Regulation Of Endothelial Cell Proliferation Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Macromolecule Metabolic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Endothelial Cell Migration Regulation Of Angiogenesis Negative Regulation Of Cell Migration Regulation Of Vasculature Development Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Cell Motility Negative Regulation Of Signal Transduction Negative Regulation Of Locomotion Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Protein Metabolic Process Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis	Nucleus Regulation Of RNA Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Regulation Of Primary Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Biosynthetic Process Regulation Of RNA Splicing Regulation Of Macromolecule Metabolic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process DNA Binding MRNA Binding Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleic Acid Binding Single-strand Selective Uracil DNA N-glycosylase Activity Regulation Of Inner Ear Auditory Receptor Cell Fate Specification Positive Regulation Of Metabolic Process
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