SPA17

Description		sperm autoantigenic protein 17
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GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cilium External Side Of Plasma Membrane Membrane Motile Cilium Sperm Fibrous Sheath Neuron Projection Sperm Principal Piece
	Molecular Function	Protein Binding Calmodulin Binding
	Biological Process	Epithelial Cilium Movement Involved In Extracellular Fluid Movement Spermatogenesis Single Fertilization Binding Of Sperm To Zona Pellucida
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 20351715)
Interacting Genes		5 interacting genes: ACTN2 AKAP3 AKAP7 MYL6B ROPN1
Entrez ID		53340
HPRD ID		12272
Ensembl ID		ENSG00000064199
Uniprot IDs		A0A172Q397 Q15506
PDB IDs		8J07
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Potassium Ion Transport Protein Kinase A Binding Structural Constituent Of Muscle Titin Z Domain Binding Intracellular Protein Localization Positive Regulation Of Cation Transmembrane Transport Regulation Of Potassium Ion Transport Actin Filament Uncapping Positive Regulation Of Monoatomic Ion Transmembrane Transport Sperm Motility Flagellated Sperm Motility Cilium Movement Involved In Cell Motility Cilium-dependent Cell Motility Phospholipase C-activating Angiotensin-activated Signaling Pathway Microspike Assembly Positive Regulation Of Monoatomic Ion Transport Cilium Movement FATZ Binding Motile Cilium Structural Constituent Of Postsynaptic Actin Cytoskeleton Channel Activator Activity LIM Domain Binding Sperm Fibrous Sheath Unconventional Myosin Complex Positive Regulation Of Endocytic Recycling Regulation Of Monoatomic Cation Transmembrane Transport Regulation Of Monoatomic Ion Transmembrane Transport Postsynaptic Actin Cytoskeleton Positive Regulation Of Actin Filament Depolymerization Negative Regulation Of Protein Localization To Cell Surface Cell Projection Titin Binding Regulation Of Metal Ion Transport Actin Filament-based Process Postsynaptic Density, Intracellular Component Postsynaptic Actin Cytoskeleton Organization Positive Regulation Of Protein Depolymerization Regulation Of Monoatomic Ion Transport Pseudopodium Microtubule-based Movement Acrosome Reaction Sperm Capacitation Muscle Myosin Complex Actin-myosin Filament Sliding Muscle Filament Sliding Angiotensin-activated Signaling Pathway Regulation Of Endocytic Recycling Postsynaptic Cytoskeleton Organization Regulation Of Membrane Potential Positive Regulation Of Cation Channel Activity
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