TMED9 and DDX54

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		TMED9	DDX54
Description		transmembrane p24 trafficking protein 9	DEAD-box helicase 54
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GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Synaptic Vesicle Membrane Transport Vesicle COPII-coated ER To Golgi Transport Vesicle Trans-Golgi Network Transport Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Extracellular Exosome	Nucleus Nucleoplasm Nucleolus Golgi Apparatus Membrane
	Molecular Function	Protein Binding Syntaxin Binding	Nucleotide Binding Nucleic Acid Binding Transcription Corepressor Activity RNA Binding RNA Helicase Activity Helicase Activity Signaling Receptor Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity Nuclear Estrogen Receptor Binding
	Biological Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Positive Regulation Of Organelle Organization Protein Transport Protein Exit From Endoplasmic Reticulum Early Endosome To Golgi Transport COPI Coating Of Golgi Vesicle	RRNA Processing RNA Processing RNA Metabolic Process Estrogen Receptor Signaling Pathway Negative Regulation Of DNA-templated Transcription
Pathways		COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Body mass index ( 26426971) Response to fenofibrate (adiponectin levels) ( 23149075)
Interacting Genes		14 interacting genes: AQP9 CDC42 CKMT2 COPZ1 DDX54 ITM2A MTF2 NMT2 PLPPR2 SEC22A SEC23B THAP8 TMEM60 YTHDF1	21 interacting genes: APP CASK CSNK2A1 DVL3 DYNLT1 ESR1 ESR2 NEDD4 NEDD4L NR3C1 PGR PJA1 POLR2G PTPRD RNF10 SEMA4A SMURF1 TMED9 USP7 YWHAE ZNF394
Entrez ID		54732	79039
HPRD ID		09975	13129
Ensembl ID		ENSG00000184840	ENSG00000123064
Uniprot IDs		Q9BVK6	Q8TDD1
PDB IDs		9CJK 9CJL	8FKT 8FKU 8FKV 8FKW 8FKX 8FKY
Enriched GO Terms of Interacting Partners?			Estrogen Response Element Binding Steroid Binding Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Nuclear Receptor-mediated Signaling Pathway Intracellular Receptor Signaling Pathway Nuclear Receptor Activity Hormone-mediated Signaling Pathway Receptor Catabolic Process Nuclear Steroid Receptor Activity Positive Regulation Of Catabolic Process Symbiont-mediated Disruption Of Host Cell PML Body Positive Regulation Of Metabolic Process Protein Ubiquitination Enzyme Binding Nuclear Estrogen Receptor Activity Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Regulation Of Cell Morphogenesis Positive Regulation Of Macromolecule Metabolic Process Protein Modification By Small Protein Conjugation Regulation Of Toll-like Receptor Signaling Pathway Nuclear Receptor-mediated Corticosteroid Signaling Pathway Intracellular Signal Transduction Macromolecule Catabolic Process Phosphoserine Residue Binding Negative Regulation Of Potassium Ion Export Across Plasma Membrane Regulation Of Synapse Organization Receptor Metabolic Process Regulation Of RNA Metabolic Process Protein Targeting To Vacuole Sodium Channel Inhibitor Activity Post-translational Protein Modification Protein Monoubiquitination Regulation Of Transcription By RNA Polymerase II Regulation Of Cellular Component Organization Regulation Of Anatomical Structure Morphogenesis Regulation Of Metal Ion Transport Regulation Of Primary Metabolic Process Ubiquitin Protein Ligase Activity Establishment Of Protein Localization To Vacuole Regulation Of Dendrite Morphogenesis Signal Transduction Potassium Channel Inhibitor Activity Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Protein Catabolic Process Protein Catabolic Process Regulation Of Potassium Ion Transmembrane Transport Regulation Of DNA-templated Transcription Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Biosynthetic Process
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