TMED9 and COPZ1

Number of citations of the paper that reports this interaction (PubMedID 9472029)
69

Data Source:
BioGRID (unspecified method)

		TMED9	COPZ1
Description		transmembrane p24 trafficking protein 9	coat protein complex I subunit zeta 1
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GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Synaptic Vesicle Membrane Transport Vesicle COPII-coated ER To Golgi Transport Vesicle Trans-Golgi Network Transport Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Extracellular Exosome	Golgi Membrane Cytoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Membrane Membrane Coat COPI Vesicle Coat Transport Vesicle COPI-coated Vesicle Membrane Cytoplasmic Vesicle
	Molecular Function	Protein Binding Syntaxin Binding
	Biological Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Positive Regulation Of Organelle Organization Protein Transport Protein Exit From Endoplasmic Reticulum Early Endosome To Golgi Transport COPI Coating Of Golgi Vesicle	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Protein Transport Vesicle-mediated Transport
Pathways		COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic	COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Chronotype ( 30696823) Hematocrit ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean platelet volume ( 22139419 24026423 27863252 32888494) Meat-related diet ( 32066663) Platelet count ( 23263863 32888494 29403010) Platelet distribution width ( 32888494) Plateletcrit ( 32888494) Red blood cell count ( 27863252 32888494) Red cell distribution width ( 27863252 32888494) Refractive error ( 32231278) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		14 interacting genes: AQP9 CDC42 CKMT2 COPZ1 DDX54 ITM2A MTF2 NMT2 PLPPR2 SEC22A SEC23B THAP8 TMEM60 YTHDF1	6 interacting genes: APP COPG1 COPG2 TMED10 TMED9 UGT1A1
Entrez ID		54732	22818
HPRD ID		09975	16738
Ensembl ID		ENSG00000184840	ENSG00000111481
Uniprot IDs		Q9BVK6	P61923
PDB IDs		9CJK 9CJL	2HF6 5MC7
Enriched GO Terms of Interacting Partners?			Endoplasmic Reticulum-Golgi Intermediate Compartment Transport Vesicle Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Endoplasmic Reticulum Golgi Vesicle Transport COPI Coating Of Golgi Vesicle Endoplasmic Reticulum Membrane Intracellular Transport Vesicle-mediated Transport COPI-coated Vesicle COPI Vesicle Coat Trans-Golgi Network Transport Vesicle Intracellular Protein Transport COPI-coated Vesicle Membrane Golgi Apparatus Transport Along Microtubule Golgi Membrane Cytoskeleton-dependent Intracellular Transport Cellular Localization Establishment Of Localization In Cell Microtubule-based Transport Membrane Coat Intra-Golgi Vesicle-mediated Transport Vesicle Coating COPII-coated ER To Golgi Transport Vesicle Cytoplasmic Vesicle Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Syntaxin Binding Regulation Of Amyloid Precursor Protein Catabolic Process Protein Transport Microtubule-based Movement Secretion By Cell Positive Regulation Of Interleukin-1 Production Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Cytosol To ERGIC Protein Transport Protein Localization To ERGIC COPI-coated Vesicle Budding Organelle Transport Along Microtubule Establishment Of Protein Localization Secretion Acetylcholine Receptor Activator Activity Regulation Of Interleukin-1 Production Lipoprotein Particle Positive Regulation Of Protein Import Golgi Organization
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