RBFOX1 and MAOB

		RBFOX1	MAOB
Description		RNA binding fox-1 homolog 1	monoamine oxidase B
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Trans-Golgi Network Cytoplasmic Stress Granule Nuclear Stress Granule	Mitochondrion Mitochondrial Envelope Mitochondrial Outer Membrane Membrane
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding	Protein Binding Primary Methylamine Oxidase Activity Electron Transfer Activity Oxidoreductase Activity Flavin Adenine Dinucleotide Binding Monoamine Oxidase Activity
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Nervous System Development RNA Splicing Regulation Of RNA Splicing RNA Transport	Substantia Nigra Development Dopamine Catabolic Process Hydrogen Peroxide Biosynthetic Process
Pathways		MECP2 regulates transcription factors	Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB
Drugs			Amphetamine Amphetamine Phentermine Procaine Tranylcypromine Phenelzine Zonisamide Selegiline Pioglitazone Procarbazine Moclobemide Moclobemide Isocarboxazid Ephedra sinica root Rasagiline MMDA 4-Methoxyamphetamine Metamfetamine Pargyline Isatin (R)-N-methyl-N-2-propynyl-1-indanamine Farnesol N-Dodecyl-N,N-Dimethyl-3-Ammonio-1-Propanesulfonate Flavin adenine dinucleotide N-Propargyl-1(S)-Aminoindan Dodecyldimethylamine N-oxide 5-Hydroxy-N-Propargyl-1(R)-Aminoindan N-METHYL-N-[(1R)-1-METHYL-2-PHENYLETHYL]PROP-2-EN-1-AMINE Nialamide Nomifensine Zimelidine Safinamide 7-[(3-CHLOROBENZYL)OXY]-2-OXO-2H-CHROMENE-4-CARBALDEHYDE 7-[(3-CHLOROBENZYL)OXY]-4-[(METHYLAMINO)METHYL]-2H-CHROMEN-2-ONE N-(2-AMINOETHYL)-P-CHLOROBENZAMIDE (1Z)-4-(4-FLUOROPHENYL)-2-METHYLIDENEBUTAN-1-IMINE 4-HYDROXY-N-PROPARGYL-1(R)-AMINOINDAN (S)-(+)-2-[4-(FLUOROBENZYLOXY-BENZYLAMINO)PROPIONAMIDE] Viloxazine Flortaucipir F-18 Vafidemstat
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Adult body size ( 32376654) Adverse response to inhaled corticosteroid treatment x age interaction in asthma ( 32119686) Age at first sexual intercourse ( 34211149) Albumin-globulin ratio ( 29403010) Allergic rhinitis ( 25085501) Alzheimer's disease ( 33074286) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Anxiety ( 33859377) Bitter alcoholic beverage consumption ( 31046077) Bitter non-alcoholic beverage consumption ( 31046077) Body mass index ( 28892062 25673413) Brain glucose metabolism (fluorodeoxyglucose uptake) ( 30596066) Brain volume in infants (cerebrospinal fluid) ( 28763065) Cataracts ( 34127677) Cerebellum white matter volume ( 31530798) Chronotype ( 30696823) Cocaine dependence ( 31212010) Cognitive decline rate in late mild cognitive impairment ( 26252872) Depression ( 33859377 29700475) Evening vs. morning chronotype (sMEQ score) ( 32579418) Extraversion ( 27918536) Feeling worry ( 29500382) Femur bone mineral density x serum urate levels interaction ( 34046847) General cognitive ability ( 29844566) General risk tolerance (MTAG) ( 30643258) Glaucoma ( 25027321) HDL cholesterol levels in HIV infection ( 33109212) High myopia ( 31816047) Hydrolysed wheat protein allergy ( 31301374) Hyperopia ( 25233373) Hypertrophic cardiomyopathy (sarcomere positive) ( 33495597) Insomnia symptoms (never/rarely vs. usually) ( 30804566) Intelligence (MTAG) ( 29326435) Intracranial aneurysm ( 29531279) joint destruction in rheumatoid arthritis (rapid vs slow) ( 33585033) Major depressive disorder ( 29728651 27479909) Mental health study participation (completed survey) ( 31263887) Metabolite levels ( 31628463) Myopia ( 27182965 25233373) Neurociticism ( 29500382) Neurofibrillary tangles ( 31497858) Neuroticism ( 29255261) Nickel levels ( 26025379) Nontraumatic osteonecrosis of the femoral head ( 32701715) Obesity (extreme) ( 31852448) Obesity-related traits ( 23251661) Optic disc size ( 31809533) Photic sneeze reflex ( 27182965) Pit-and-Fissure caries ( 24556642) Refractive astigmatism ( 30306274) Refractive error ( 23396134 32231278 23474815) Renal cell carcinoma ( 31231134) Rheumatoid arthritis ( 30423114) Severe insulin-resistant type 2 diabetes ( 34737425) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Systemising ( 31508503) Systolic blood pressure ( 30224653) Systolic blood pressure and diastolic blood pressure (bivariate analysis) ( 33539483) tricyclic pyrone compound response (IC50) ( 33610756) Triglyceride levels ( 34074324) Type 1 diabetes autoantibodies in high risk HLA genotype individuals (time to event) ( 29310926) Type 2 diabetes ( 30130595) Worry too long after an embarrassing experience ( 29500382)
Interacting Genes		49 interacting genes: AGR2 ALG13 ARID5A ATN1 ATXN1 ATXN1L ATXN2 BHLHE40 C1orf94 CELF3 CRX DAB1 DAZAP2 DMRTB1 DVL2 FAM168A GCA HNRNPF HSFX1 HSFY1 HYPK KIFAP3 LASP1 LZTS2 MAGED1 NOC2L NUMBL P4HA3 PCBP4 POGZ PRR20A PRRC2A PSMF1 QKI RBFOX2 RBFOX3 RBM24 RBM47 RBPMS RBPMS2 RHOXF2 SIRPB1 SNRPN SPMIP9 STRBP TNIP1 TOLLIP UBL3 VENTX	6 interacting genes: COX20 FGF14 NFYB RHBDD2 SRPK1 TRIM54
Entrez ID		54715	4129
HPRD ID		16091	02401
Ensembl ID		ENSG00000078328	ENSG00000069535
Uniprot IDs		A0A6Q8PH77 A0A804HJM2 A0A804HKG7 B7Z1U7 F8VZG9 Q59HD3 Q9NWB1 X5D7T5 X5DNY3 X5DP44	B7Z242 P27338
PDB IDs		2ERR 2N82 4ZKA 7VRL	1GOS 1OJ9 1OJA 1OJC 1OJD 1S2Q 1S2Y 1S3B 1S3E 2BK3 2BK4 2BK5 2BYB 2C64 2C65 2C66 2C67 2C70 2C72 2C73 2C75 2C76 2V5Z 2V60 2V61 2VRL 2VRM 2VZ2 2XCG 2XFN 2XFO 2XFP 2XFQ 2XFU 3PO7 3ZYX 4A79 4A7A 4CRT 5MRL 6FVZ 6FW0 6FWC 6RKB 6RKP 6RLE 6YT2 7B0V 7B0Z 7P4F 7P4H 7ZW3 9FJT
Enriched GO Terms of Interacting Partners?		Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Splicing Regulation Of MRNA Processing Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of MRNA Metabolic Process MRNA Binding RNA Binding Nucleic Acid Binding Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Cytoplasmic Stress Granule RNA Splicing Nucleus Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process MRNA Processing POZ Domain Binding MRNA 3'-UTR Binding MRNA CDS Binding Cytoplasm Regulation Of Metabolic Process Stress Granule Assembly Positive Regulation Of 3'-UTR-mediated MRNA Stabilization Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process RNA Processing Negative Regulation Of MRNA Metabolic Process Regulation Of MRNA Stability Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Stability MRNA Metabolic Process Pre-mRNA Intronic Binding Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Neurogenesis Positive Regulation Of RNA Metabolic Process Negative Regulation Of RNA Metabolic Process MRNA Stabilization DNA Binding Pre-mRNA Binding Protein Binding Transcription Coactivator Activity Negative Regulation Of MRNA Catabolic Process RNA Stabilization Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Nervous System Development
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?