RBFOX2 and RBM22

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, two hybrid)

		RBFOX2	RBM22
Gene Name		RNA binding protein, fox-1 homolog (C. elegans) 2	RNA binding motif protein 22
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Nucleus Nucleoplasm Cytoplasm Catalytic Step 2 Spliceosome
	Molecular Function	Nucleotide Binding Transcription Corepressor Activity RNA Binding MRNA Binding Protein Binding Transcription Factor Binding Poly(A) RNA Binding	Nucleotide Binding Nucleocytoplasmic Transporter Activity SnRNA Binding Pre-mRNA Binding Poly(A) RNA Binding Metal Ion Binding Calcium-dependent Protein Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Regulation Of Definitive Erythrocyte Differentiation RNA Metabolic Process Radial Glia Guided Migration Of Purkinje Cell Intracellular Estrogen Receptor Signaling Pathway Regulation Of Cell Proliferation Negative Regulation Of Transcription, DNA-templated Dendrite Morphogenesis Neuromuscular Process Controlling Balance	Protein Import Into Nucleus, Translocation MRNA Splicing, Via Spliceosome Positive Regulation Of RNA Splicing Cellular Response To Drug MRNA Cis Splicing, Via Spliceosome Positive Regulation Of Intracellular Protein Transport
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		50 interactors: APH1A ATN1 ATXN1 ATXN1L BOLL BRD7 C1orf94 CAMK2B CHAF1A DAB1 DAZAP2 DDX5 DEDD2 DMRTB1 ELAVL1 ELAVL2 ESR1 ESR2 GLIS2 GTF2A1L HNRNPAB HNRNPF HNRNPH2 HNRNPK KHDRBS1 MAGED1 MAPK1IP1L MED7 NAF1 NR2E3 POLR3D PSMA3 PSMF1 PTBP1 QKI RBFOX1 RBM22 RBM23 RBM42 RBPMS RERE RHOXF2 RNF8 SF3A1 SMN1 SNRPC TOLLIP U2AF2 VAC14 ZNF137P	9 interactors: AQR CEP55 HNRNPUL1 PRNP RBFOX2 RBM4 RNU6-1 RNU6-50P RNU6-6P
Entrez ID		23543	55696
HPRD ID		15231	10186
Ensembl ID		ENSG00000100320	ENSG00000086589
Uniprot IDs		O43251	Q9NW64
PDB IDs		2CQ3	2YTC
Enriched GO Terms of Interacting Partners?		Gene Expression RNA Metabolic Process RNA Processing Cellular Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Processing Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process MRNA Metabolic Process Regulation Of RNA Metabolic Process RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Negative Regulation Of Gene Expression Transcription, DNA-templated RNA Biosynthetic Process Regulation Of RNA Splicing Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Cellular Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Protein Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Regulation Of MRNA Processing Positive Regulation Of Cellular Protein Metabolic Process Metabolic Process DNA-templated Transcription, Initiation	RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Regulation Of RNA Splicing Negative Regulation Of Calcineurin-NFAT Signaling Cascade IRES-dependent Translational Initiation Cap-independent Translational Initiation Radial Glia Guided Migration Of Purkinje Cell Regulation Of Definitive Erythrocyte Differentiation MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Circadian Regulation Of Translation Cellular Response To Copper Ion Negative Regulation Of Calcium-mediated Signaling Negative Regulation Of Translation In Response To Stress Negative Regulation Of Translation Involved In Gene Silencing By MiRNA Negative Regulation Of Interleukin-17 Production Cytoplasmic Translational Initiation Regulation Of Calcineurin-NFAT Signaling Cascade Negative Regulation Of Activated T Cell Proliferation RNA Metabolic Process Cytoplasmic Translation Regulation Of Translation In Response To Stress Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Interleukin-2 Production Cellular Copper Ion Homeostasis Cell Separation After Cytokinesis Negative Regulation Of Translational Initiation Negative Regulation Of T Cell Receptor Signaling Pathway Gene Expression Response To Copper Ion Entrainment Of Circadian Clock By Photoperiod Copper Ion Homeostasis Cell Migration In Hindbrain Photoperiodism Entrainment Of Circadian Clock Response To Arsenic-containing Substance Response To External Stimulus Cell Morphogenesis Involved In Neuron Differentiation Negative Regulation Of Interferon-gamma Production Gene Silencing By MiRNA Regulation Of Activated T Cell Proliferation Regulation Of Erythrocyte Differentiation Regulation Of Potassium Ion Transmembrane Transport Neuron Projection Morphogenesis Posttranscriptional Gene Silencing
Tagcloud ?		aberrant altering biology discussing editing emerging fmrp focus fus hub huc hud hur neurological nova players polyadenylation processing qki rbp rbps rna rnas roles splicing steps surveillance translational
Tagcloud (Difference) ?		aberrant altering biology discussing editing emerging fmrp focus fus hub huc hud hur neurological nova players polyadenylation processing qki rbp rbps rna rnas roles splicing steps surveillance translational
Tagcloud (Intersection) ?