POU3F3 and SOX11

Number of citations of the paper that reports this interaction (PMID 9632656)
52

Data Source:
HPRD (in vitro)

		POU3F3	SOX11
Gene Name		POU class 3 homeobox 3	SRY (sex determining region Y)-box 11
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Cytoplasm
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding HMG Box Domain Binding	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Transcription Coactivator Activity Enhancer Sequence-specific DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Translation Factor Activity, Nucleic Acid Binding
	Biological Process	Transcription, DNA-templated Central Nervous System Development Positive Regulation Of Cell Proliferation Positive Regulation Of Gene Expression Cerebral Cortex Radially Oriented Cell Migration Forebrain Ventricular Zone Progenitor Cell Division Negative Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Metanephric Ascending Thin Limb Development Metanephric Macula Densa Development Metanephric Thick Ascending Limb Development Metanephric Loop Of Henle Development Metanephric DCT Cell Differentiation	Negative Regulation Of Transcription From RNA Polymerase II Promoter Skeletal System Development Kidney Development Neural Tube Formation Lens Morphogenesis In Camera-type Eye Outflow Tract Morphogenesis Cardiac Ventricle Formation Noradrenergic Neuron Differentiation Transcription, DNA-templated Translation Positive Regulation Of Cell Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Oligodendrocyte Development Glial Cell Proliferation Neural Crest Cell Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Spinal Cord Development Glial Cell Development Neuron Differentiation Positive Regulation Of BMP Signaling Pathway Positive Regulation Of Hippo Signaling Skeletal Muscle Cell Differentiation Positive Regulation Of Neuron Differentiation Positive Regulation Of Osteoblast Differentiation Positive Regulation Of Ossification Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Hormone Secretion Sympathetic Nervous System Development Embryonic Digestive Tract Morphogenesis Embryonic Skeletal System Morphogenesis Negative Regulation Of Lymphocyte Proliferation Positive Regulation Of Neurogenesis Hard Palate Development Soft Palate Development Limb Bud Formation Negative Regulation Of Glial Cell Proliferation Ventricular Septum Morphogenesis Lung Morphogenesis Negative Regulation Of Cell Death Neuroepithelial Cell Differentiation Eyelid Development In Camera-type Eye Somite Development Cornea Development In Camera-type Eye Closure Of Optic Fissure Signal Transduction Involved In Cell Cycle Checkpoint Positive Regulation Of Stem Cell Proliferation Negative Regulation Of Transcription Regulatory Region DNA Binding Positive Regulation Of Lens Epithelial Cell Proliferation
Pathways
Drugs
Diseases
GWAS		Response to taxane treatment (docetaxel) ( 23006423)	Chronic kidney disease ( 20383146) Crohn's disease ( 23266558) Obesity-related traits ( 23251661)
Protein-Protein Interactions		5 interactors: POU3F4 PPP1R15A SOX10 SOX11 SOX8	2 interactors: POU3F2 POU3F3
Entrez ID		5455	6664
HPRD ID		03922	02940
Ensembl ID			ENSG00000176887
Uniprot IDs		P20264	P35716
PDB IDs
Enriched GO Terms of Interacting Partners?		Autonomic Nervous System Development Neural Crest Cell Development Oligodendrocyte Differentiation Neural Crest Cell Differentiation Regulation Of Gliogenesis Mesenchymal Cell Development Mesenchymal Cell Differentiation Enteric Nervous System Development Glial Cell Differentiation Mesenchyme Development Transcription From RNA Polymerase II Promoter Gliogenesis Stem Cell Development Central Nervous System Development Negative Regulation Of Cell Death Stem Cell Differentiation Embryo Development Neuroepithelial Cell Differentiation Neural Crest Cell Migration Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Neurogenesis Positive Regulation Of Gliogenesis Tube Morphogenesis Skeletal Muscle Cell Differentiation Positive Regulation Of Macromolecule Biosynthetic Process Digestive Tract Morphogenesis Positive Regulation Of Gene Expression Regulation Of Cell Death Generation Of Neurons Positive Regulation Of Cell Development Positive Regulation Of Stem Cell Proliferation Positive Regulation Of Cellular Biosynthetic Process Epithelial Cell Differentiation Neurogenesis Sensory Organ Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Embryonic Morphogenesis Peripheral Nervous System Development Regulation Of Transcription, DNA-templated Positive Regulation Of Lens Epithelial Cell Proliferation Positive Regulation Of Translational Initiation In Response To Stress Positive Regulation Of Hippo Signaling Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Stem Cell Proliferation Regulation Of RNA Metabolic Process Regulation Of Neurogenesis Tube Development Negative Regulation Of Cellular Metabolic Process Camera-type Eye Morphogenesis	Forebrain Ventricular Zone Progenitor Cell Division Cell Proliferation In Forebrain Cerebral Cortex Radially Oriented Cell Migration Cerebral Cortex Cell Migration Telencephalon Cell Migration Forebrain Cell Migration Neural Precursor Cell Proliferation Cerebral Cortex Development Pallium Development Metanephric Macula Densa Development Metanephric DCT Cell Differentiation Telencephalon Development Neurohypophysis Development Metanephric Thick Ascending Limb Development Cell Division Forebrain Development Metanephric Ascending Thin Limb Development Metanephric Distal Convoluted Tubule Development Metanephric Loop Of Henle Development Hypothalamus Cell Differentiation Metanephric Distal Tubule Development Cell Proliferation Loop Of Henle Development Cell Differentiation Involved In Metanephros Development Brain Development Distal Tubule Development Head Development Positive Regulation Of Cell Proliferation Cell Migration Cell Motility Metanephric Nephron Tubule Development Central Nervous System Development Astrocyte Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Hypothalamus Development Epithelium Development Metanephric Epithelium Development Locomotion Positive Regulation Of Transcription, DNA-templated Cell Differentiation Involved In Kidney Development Astrocyte Differentiation Myelination In Peripheral Nervous System Regulation Of Cell Proliferation Movement Of Cell Or Subcellular Component Positive Regulation Of Macromolecule Biosynthetic Process Schwann Cell Development Positive Regulation Of Gene Expression Positive Regulation Of Multicellular Organism Growth Positive Regulation Of Cellular Biosynthetic Process Pituitary Gland Development
Tagcloud ?		aberrantly affiliate colonies densely dnmt dnmt3a dnmt3b eca escc guangzhou hairpin hypermethylated intergenic islands knocked lentiviral linc lincrna lincrnas neighboring noncoding nontumor pharmacologic rnas slowly soochow te thousands tylectomy	barr bcl6 blastoid ccnd1 cd10 cd20 cd5 clinicopathologic coexistence convincingly cooperate differentiating dlbcl entity epstein igh immunophenotypic mantle molecularly morphologic mum1 pitfall pleomorphic pose rearrangement rearrangements relapsed rendered thorough
Tagcloud (Difference) ?		aberrantly affiliate colonies densely dnmt dnmt3a dnmt3b eca escc guangzhou hairpin hypermethylated intergenic islands knocked lentiviral linc lincrna lincrnas neighboring noncoding nontumor pharmacologic rnas slowly soochow te thousands tylectomy	barr bcl6 blastoid ccnd1 cd10 cd20 cd5 clinicopathologic coexistence convincingly cooperate differentiating dlbcl entity epstein igh immunophenotypic mantle molecularly morphologic mum1 pitfall pleomorphic pose rearrangement rearrangements relapsed rendered thorough
Tagcloud (Intersection) ?