POLR2J and SATB1

Number of citations of the paper that reports this interaction (PMID 12036295)
1

Data Source:
BioGRID (two hybrid, pull down)
HPRD (two hybrid, in vitro)

		POLR2J	SATB1
Gene Name		polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa	SATB homeobox 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm DNA-directed RNA Polymerase II, Core Complex	Nucleus Nucleoplasm Nuclear Heterochromatin Nuclear Matrix PML Body
	Molecular Function	RNA Polymerase II Activity DNA Binding DNA-directed RNA Polymerase Activity Protein Binding LRR Domain Binding Protein Dimerization Activity	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Chromatin Binding Double-stranded DNA Binding Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome DNA Repair Transcription-coupled Nucleotide-excision Repair Nucleotide-excision Repair Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter 7-methylguanosine MRNA Capping RNA Splicing Gene Expression Viral Process PiRNA Metabolic Process Somatic Stem Cell Maintenance Positive Regulation Of Viral Transcription	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Chromatin Remodeling Transcription, DNA-templated Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Epidermis Development Viral Process Histone Methylation CD4-positive, Alpha-beta T Cell Differentiation CD8-positive, Alpha-beta T Cell Differentiation Activated T Cell Proliferation Reflex
Pathways		RNA Polymerase II Promoter Escape mRNA Splicing Formation of HIV-1 elongation complex containing HIV-1 Tat PIWI-interacting RNA (piRNA) biogenesis Nucleotide Excision Repair RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Abortive elongation of HIV-1 transcript in the absence of Tat HIV Infection Regulatory RNA pathways Formation of the Early Elongation Complex Tat-mediated elongation of the HIV-1 transcript Tat-mediated HIV elongation arrest and recovery Formation of transcription-coupled NER (TC-NER) repair complex RNA Pol II CTD phosphorylation and interaction with CE RNA Polymerase II Pre-transcription Events Dual incision reaction in TC-NER Influenza Life Cycle HIV elongation arrest and recovery HIV Life Cycle HIV Transcription Initiation Influenza Viral RNA Transcription and Replication RNA Pol II CTD phosphorylation and interaction with CE Transcriptional regulation of pluripotent stem cells RNA Polymerase II HIV Promoter Escape HIV Transcription Elongation POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation Transcriptional regulation by small RNAs Processing of Capped Intron-Containing Pre-mRNA mRNA Capping mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway MicroRNA (miRNA) biogenesis Influenza Infection Pausing and recovery of Tat-mediated HIV elongation Late Phase of HIV Life Cycle Formation of RNA Pol II elongation complex RNA Polymerase II Transcription Initiation And Promoter Clearance Pausing and recovery of HIV elongation Formation of HIV elongation complex in the absence of HIV Tat Transcription-coupled NER (TC-NER) Viral Messenger RNA Synthesis Formation of the HIV-1 Early Elongation Complex RNA Polymerase II Transcription Initiation Transcription of the HIV genome RNA Polymerase II Transcription Elongation	Apoptotic cleavage of cellular proteins Programmed Cell Death Apoptotic execution phase
Drugs
Diseases
GWAS			Platelet counts ( 22139419)
Protein-Protein Interactions		8 interactors: AATF BAG6 CD14 LARP1B POLR1C POLR2C POLR2K SATB1	23 interactors: BAZ1A CASP6 CBX4 CHD3 CUX1 DYT10 EP300 GATA3 HDAC1 KAT2B MTA2 PIAS1 PIAS3 PIAS4 POLR2J SIRT1 SMARCA5 SUMO1 SUMO1P1 SUMO3 TOPORS UBE2I UBR5
Entrez ID		5439	6304
HPRD ID		16038	03647
Ensembl ID		ENSG00000005075	ENSG00000182568
Uniprot IDs		P52435	Q01826
PDB IDs			1YSE 2L1P 2O49 2O4A 3NZL 3TUO
Enriched GO Terms of Interacting Partners?		DNA-templated Transcription, Elongation Termination Of RNA Polymerase III Transcription Transcription Elongation From RNA Polymerase III Promoter Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter DNA-templated Transcription, Initiation 7-methylguanosine MRNA Capping Transcription From RNA Polymerase I Promoter PiRNA Metabolic Process 7-methylguanosine RNA Capping Cellular Response To DNA Damage Stimulus Response To Stress Transcription-coupled Nucleotide-excision Repair Positive Regulation Of Viral Transcription Transcription From RNA Polymerase III Promoter Apoptotic Process Programmed Cell Death Immune System Process Positive Regulation Of Cytokine Production Cell Death Death Transcription Elongation From RNA Polymerase II Promoter Somatic Stem Cell Maintenance Regulation Of Viral Transcription Positive Regulation Of Viral Process DNA-templated Transcription, Termination Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Type I Interferon Production Nucleotide-excision Repair Regulation Of Cytokine Production Viral Process Regulation Of Type I Interferon Production Regulation Of Gene Expression Cellular Response To Stress Response To Stimulus Stem Cell Maintenance Regulation Of Viral Process Transcription Initiation From RNA Polymerase II Promoter Innate Immune Response Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Negative Regulation Of Superoxide Anion Generation Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression, Epigenetic Tail-anchored Membrane Protein Insertion Into ER Membrane MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Stem Cell Development Transcription, DNA-templated Protein Insertion Into ER Membrane	Protein Sumoylation Peptidyl-lysine Modification Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Protein Modification By Small Protein Conjugation RNA Biosynthetic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Peptidyl-amino Acid Modification Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Chromatin Modification Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process RNA Metabolic Process Nitrogen Compound Metabolic Process Chromatin Organization Positive Regulation Of Metabolic Process Gene Expression Chromatin Remodeling Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Cellular Protein Modification Process Chromosome Organization Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Sumoylation Positive Regulation Of Cellular Biosynthetic Process Cellular Metabolic Process Regulation Of Protein Metabolic Process Biosynthetic Process Regulation Of Protein Sumoylation Positive Regulation Of Transcription, DNA-templated Regulation Of Androgen Receptor Signaling Pathway Cellular Protein Metabolic Process
Tagcloud ?			biomarker clinicopathologic confidence depth endometrial federation gynecology hazards histological international interval invasion lymphatic metastasis myometrial node obstetrics organizer overexpressed parameter predicting prognostic rich serve serves special treating untreated worse
Tagcloud (Difference) ?			biomarker clinicopathologic confidence depth endometrial federation gynecology hazards histological international interval invasion lymphatic metastasis myometrial node obstetrics organizer overexpressed parameter predicting prognostic rich serve serves special treating untreated worse
Tagcloud (Intersection) ?