PPIL3 and CENATAC

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PPIL3	CENATAC
Description		peptidylprolyl isomerase like 3	centrosomal AT-AC splicing factor
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GO Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex Catalytic Step 2 Spliceosome	Cytoplasm Centrosome Cytoskeleton
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Isomerase Activity	Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing Protein Folding RNA Splicing	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Negative Regulation Of Centrosome Duplication Regulation Of Protein Catabolic Process Chromosome Separation
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Breast cancer ( 27117709) Breast cancer (estrogen-receptor negative) ( 27117709) Triptolide cytotoxicity ( 26121980)
Interacting Genes		10 interacting genes: CENATAC DMRTB1 PCBP1 PHC1 RPS13 SHARPIN SLU7 TAB2 TAB3 YTHDF1	7 interacting genes: MESD MRPL38 NAT10 NDOR1 PPIL3 SIRT1 ZNF114
Entrez ID		53938	338657
HPRD ID		15163	13234
Ensembl ID		ENSG00000240344	ENSG00000186166
Uniprot IDs		A0A024R3V4 A0A0S2Z5A8 Q9H2H8	Q86UT8
PDB IDs		1XYH 2OJU 2OK3 8C6J	8Y6O
Enriched GO Terms of Interacting Partners?			Regulation Of Centrosome Cycle NAD-dependent Protein Decrotonylase Activity Histone H4K12 Deacetylase Activity, Hydrolytic Mechanism Protein Acetylation Negative Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Regulation Of Centrosome Duplication Maintenance Of Nucleus Location Histone Decrotonylase Activity, NAD-dependent Histone H3K14 Deacetylase Activity, NAD-dependent Negative Regulation Of Cellular Response To Testosterone Stimulus Histone H3K Deacetylase Activity NADPH-iron-sulfur [2Fe-2S] Protein Oxidoreductase Activity TRNA Acetylation MRNA N-acetyltransferase Activity TRNA Cytidine N4-acetyltransferase Activity TRNA Wobble Cytosine Modification RRNA Acetylation Involved In Maturation Of SSU-rRNA 18S RRNA Cytidine N-acetyltransferase Activity NAD-dependent Protein Lysine Delactylase Activity Regulation Of Cellular Response To Testosterone Stimulus Behavioral Response To Starvation Negative Regulation Of Peptidyl-lysine Acetylation Histone H4K16 Deacetylase Activity, NAD-dependent Histone H3K9 Deacetylase Activity, NAD-dependent NAD-dependent Protein-lysine Depropionylase Activity Negative Regulation Of Prostaglandin Biosynthetic Process Protein Depropionylation Positive Regulation Of Macrophage Apoptotic Process ENoSc Complex Positive Regulation Of CAMP-dependent Protein Kinase Activity NADPH-hemoprotein Reductase Activity Negative Regulation Of Protein Acetylation Negative Regulation Of Triglyceride Biosynthetic Process Triglyceride Mobilization Pyrimidine Dimer Repair By Nucleotide-excision Repair HLH Domain Binding Oxidoreductase Activity, Acting On NAD(P)H, Heme Protein As Acceptor Histone Deacetylase Activity, NAD-dependent Regulation Of CAMP-dependent Protein Kinase Activity RDNA Heterochromatin Chromosome, Telomeric Region Keratin Filament Binding Protein Folding RDNA Heterochromatin Formation Regulation Of Endodeoxyribonuclease Activity Stress-induced Premature Senescence NAD-dependent Protein Lysine Deacetylase Activity Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Ovulation From Ovarian Follicle
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