PPIL3 and SLU7

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, two hybrid, two hybrid)
HPRD (two hybrid)

		PPIL3	SLU7
Gene Name		peptidylprolyl isomerase (cyclophilin)-like 3	SLU7 splicing factor homolog (S. cerevisiae)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Membrane Nuclear Speck Small Nuclear Ribonucleoprotein Complex Intracellular Membrane-bounded Organelle Catalytic Step 2 Spliceosome
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding	Second Spliceosomal Transesterification Activity Protein Binding Zinc Ion Binding Pre-mRNA 3'-splice Site Binding
	Biological Process	MRNA Splicing, Via Spliceosome Protein Peptidyl-prolyl Isomerization Protein Folding	RNA Splicing, Via Transesterification Reactions Alternative MRNA Splicing, Via Spliceosome MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome Intracellular Protein Transport Cellular Response To Heat
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: PCBP1 SLU7	17 interactors: BAG2 CCDC85B CEP70 GOLGA2 GTF2I JMJD6 KDM1A KRT40 LZTS2 PCBP2 PPIG PPIL3 PRMT5 PRMT6 THAP1 WHSC1L1 ZCCHC10
Entrez ID		53938	10569
HPRD ID		15163	12074
Ensembl ID		ENSG00000240344	ENSG00000164609
Uniprot IDs		Q9H2H8	O95391
PDB IDs		1XYH 2OJU 2OK3
Enriched GO Terms of Interacting Partners?		MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing MRNA Processing MRNA 3'-splice Site Recognition MRNA Metabolic Process RNA Processing Alternative MRNA Splicing, Via Spliceosome MRNA Splice Site Selection Spliceosomal Complex Assembly Cellular Response To Heat Response To Heat Ribonucleoprotein Complex Assembly Response To Temperature Stimulus	RNA Metabolic Process Gene Expression RNA Splicing Histone Modification Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Peptidyl-amino Acid Modification RNA Processing Cellular Nitrogen Compound Metabolic Process Histone H4-R3 Methylation Chromatin Modification Transcription, DNA-templated RNA Biosynthetic Process Peptidyl-arginine N-methylation Nitrogen Compound Metabolic Process Chromatin Organization Histone Methylation Histone Arginine Methylation Peptidyl-arginine Methylation MRNA Processing Protein Methylation Histone Demethylation Protein Demethylation MRNA Metabolic Process Chromosome Organization Cellular Protein Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Protein Binding Cellular Macromolecule Biosynthetic Process Histone H3-R2 Demethylation Histone H4-R3 Demethylation Regulation Of Primitive Erythrocyte Differentiation Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Protein Folding Macromolecule Biosynthetic Process Demethylation Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Protein Peptidyl-prolyl Isomerization Histone H3-R2 Methylation Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Transition Between Slow And Fast Fiber Organelle Organization Negative Regulation Of Binding Cellular Protein Modification Process
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