PLXNA2 and IFT80

Number of citations of the paper that reports this interaction (PMID 12421765)
28

Data Source:
HPRD (two hybrid)

		PLXNA2	IFT80
Gene Name		plexin A2	intraflagellar transport 80
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Semaphorin Receptor Complex Intracellular Plasma Membrane Integral Component Of Plasma Membrane	Cytoplasm Centrosome Cilium Intraciliary Transport Particle B Primary Cilium Ciliary Tip
	Molecular Function	Protein Binding Semaphorin Receptor Activity
	Biological Process	Somitogenesis Axon Guidance Neural Tube Development Cerebellar Granule Cell Precursor Tangential Migration Regulation Of Cell Migration Centrosome Localization Pharyngeal System Development Limb Bud Formation Semaphorin-plexin Signaling Pathway	Osteoblast Differentiation Chondrocyte Differentiation Organelle Organization Smoothened Signaling Pathway Cilium Assembly Positive Regulation Of Smoothened Signaling Pathway Negative Regulation Of Epithelial Cell Proliferation Bone Morphogenesis Negative Regulation Of Non-canonical Wnt Signaling Pathway
Pathways		Axon guidance Semaphorin interactions Other semaphorin interactions Sema3A PAK dependent Axon repulsion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion CRMPs in Sema3A signaling	Organelle biogenesis and maintenance Assembly of the primary cilium Intraflagellar transport
Drugs
Diseases
GWAS		Cardiac hypertrophy ( 21348951)
Protein-Protein Interactions		6 interactors: CEMIP DHX37 FNBP4 HACE1 IFT80 UBAP2L	1 interactors: PLXNA2
Entrez ID		5362	57560
HPRD ID		03033	13853
Ensembl ID		ENSG00000076356	ENSG00000068885
Uniprot IDs		O75051	Q9P2H3
PDB IDs		3Q3J
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Kinase C Activity	Cerebellar Granule Cell Precursor Tangential Migration Hindbrain Tangential Cell Migration Limb Bud Formation Pharyngeal System Development Cell Migration In Hindbrain Centrosome Localization Semaphorin-plexin Signaling Pathway Somitogenesis Somite Development Segmentation Hindbrain Development Limb Morphogenesis Neural Tube Development Limb Development Anterior/posterior Pattern Specification
Tagcloud ?			asphyxiating bones cage cassette chondrodysplasias cilia ciliogenesis constriction dystrophy hedgehog highlighting homozygote homozygotes hypomorphic intraflagellar inversus jatd jeune malformation permits phenocopy polydactyly rib ribcage shortening situs srp thoracic
Tagcloud (Difference) ?			asphyxiating bones cage cassette chondrodysplasias cilia ciliogenesis constriction dystrophy hedgehog highlighting homozygote homozygotes hypomorphic intraflagellar inversus jatd jeune malformation permits phenocopy polydactyly rib ribcage shortening situs srp thoracic
Tagcloud (Intersection) ?