IFT80 and NMD3

		IFT80	NMD3
Description		intraflagellar transport 80	NMD3 ribosome export adaptor
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytoskeleton Cilium Intraciliary Transport Particle B Ciliary Basal Body Cell Projection Ciliary Tip 9+0 Non-motile Cilium	Nucleus Nucleoplasm Nucleolus Cytoplasm Membrane
	Molecular Function		RNA Binding Protein-macromolecule Adaptor Activity Ribosomal Large Subunit Binding
	Biological Process	Skeletal System Development Ossification Osteoblast Differentiation Endochondral Ossification Chondrocyte Differentiation Growth Plate Cartilage Development Growth Plate Cartilage Chondrocyte Differentiation Apoptotic Process Establishment Or Maintenance Of Cell Polarity Smoothened Signaling Pathway Canonical NF-kappaB Signal Transduction Cell Population Proliferation Fibroblast Growth Factor Receptor Signaling Pathway Tissue Development Gene Expression Proteasomal Protein Catabolic Process Negative Regulation Of Keratinocyte Proliferation Protein Ubiquitination Spinal Cord Development Osteoclast Differentiation Osteoblast Proliferation Multicellular Organism Growth Non-canonical Wnt Signaling Pathway Bone Mineralization Involved In Bone Maturation Intraciliary Anterograde Transport Odontogenesis Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Keratinocyte Proliferation Tooth Eruption Cilium Organization Stem Cell Differentiation Protein Stabilization Cartilage Development Limb Development Cilium Assembly Bone Development Bone Morphogenesis Articular Cartilage Development Odontoblast Differentiation Stem Cell Proliferation Receptor Localization To Non-motile Cilium Response To Inositol Non-motile Cilium Assembly Cartilage Homeostasis Negative Regulation Of Non-canonical Wnt Signaling Pathway	Ribosomal Large Subunit Export From Nucleus Protein Transport Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Protein Localization To Nucleolus
Pathways		Intraflagellar transport Intraflagellar transport
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 34315874) Aspartate aminotransferase levels ( 34315874) Bipolar disorder ( 31043756) LDL cholesterol ( 30275531) Liver enzyme levels (alanine transaminase) ( 33972514) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Malaria ( 31844061)	Chronotype ( 30696823) Interleukin-10 levels ( 22205395) Morning person ( 30696823) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		2 interacting genes: PLXNA2 UBXN10	4 interacting genes: CSNK2A1 LNX2 XPO1 YTHDF3
Entrez ID		57560	51068
HPRD ID		13853	13026
Ensembl ID		ENSG00000068885	ENSG00000169251
Uniprot IDs		Q9P2H3	C9JA08 Q96D46
PDB IDs			6LQM 6LSR 6LU8
Enriched GO Terms of Interacting Partners?			Regulation Of Translational Initiation Protein Localization To Organelle Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Kinase CK2 Complex Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Symbiont-mediated Disruption Of Host Cell PML Body Positive Regulation Of Aggrephagy Organelle Assembly Annulate Lamellae Response To Triglyceride Cellular Response To Triglyceride Tooth Eruption Articular Cartilage Development Growth Plate Cartilage Chondrocyte Differentiation Negative Regulation Of Non-canonical Wnt Signaling Pathway Bone Mineralization Involved In Bone Maturation Response To Inositol Cartilage Homeostasis Receptor Localization To Non-motile Cilium Protein Stabilization Cellular Response To Salt Ribosomal Small Subunit Export From Nucleus Ribosomal Large Subunit Export From Nucleus Odontoblast Differentiation Chondrocyte Differentiation Involved In Endochondral Bone Morphogenesis Protein Localization To Ciliary Membrane Wnt Signaling Pathway Membraneless Organelle Assembly Double-strand Break Repair Via Classical Nonhomologous End Joining Intracellular Transport Ribosomal Subunit Export From Nucleus Protein Localization To Non-motile Cilium Growth Plate Cartilage Development 9+0 Non-motile Cilium Osteoblast Proliferation Regulation Of Wnt Signaling Pathway Nuclear Export Signal Receptor Activity N6-methyladenosine-containing RNA Reader Activity Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Aggrephagy Protein Targeting To Vacuole Involved In Autophagy Regulation Of Protein Catabolic Process Regulation Of Protein Stability Negative Regulation Of Signal Transduction MRNA Methylguanosine-cap Decapping Regulation Of Proteolysis Intraciliary Anterograde Transport Regulation Of Trophoblast Cell Migration Intraciliary Transport Particle B
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