PKHD1 and CAMLG

Number of citations of the paper that reports this interaction (PMID 16243292)
8

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		PKHD1	CAMLG
Gene Name		polycystic kidney and hepatic disease 1 (autosomal recessive)	calcium modulating ligand
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Centrosome Integral Component Of Membrane Apical Plasma Membrane Anchored Component Of External Side Of Plasma Membrane Ciliary Basal Body Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome Primary Cilium Mitotic Spindle	Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Receptor Activity Protein Binding	Protein Binding Cell Adhesion Molecule Binding
	Biological Process	Kidney Development Cellular Calcium Ion Homeostasis Positive Regulation Of Cell Proliferation Regulation Of Centrosome Duplication Single Organismal Cell-cell Adhesion Regulation Of TOR Signaling Negative Regulation Of NF-kappaB Transcription Factor Activity Cilium Assembly Homeostatic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Cellular Component Movement Negative Regulation Of Protein Kinase B Signaling Regulation Of ERK1 And ERK2 Cascade	Receptor Recycling Defense Response Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Viral Process
Pathways
Drugs			Cyclosporine
Diseases
GWAS		Prostate cancer ( 17903305) Waist circumference ( 19557197) Weight loss (gastric bypass surgery) ( 23633212)	Height ( 18391951)
Protein-Protein Interactions		1 interactors: CAMLG	5 interactors: EGFR KCNA2 PKHD1 PPIB TNFRSF13B
Entrez ID		5314	819
HPRD ID		05987	03073
Ensembl ID		ENSG00000170927	ENSG00000164615
Uniprot IDs		P08F94	P49069
PDB IDs
Enriched GO Terms of Interacting Partners?		Receptor Recycling Receptor Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway	System Development Alkanesulfonate Metabolic Process Regulation Of Protein Kinase B Signaling Multicellular Organismal Development Anatomical Structure Development Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Optic Nerve Structural Organization Astrocyte Activation Regulation Of ERK1 And ERK2 Cascade Developmental Process Activation Of Phospholipase A2 Activity Positive Regulation By Host Of Viral Genome Replication Positive Regulation By Host Of Viral Process Positive Regulation Of Phospholipase A2 Activity Organ Development Response To Cobalamin Response To UV-A Response To Hydroxyisoflavone Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Superoxide Anion Generation Homeostatic Process Optic Nerve Morphogenesis Positive Regulation Of Catenin Import Into Nucleus Regulation Of Cell Proliferation Regulation Of Phospholipase A2 Activity Regulation Of Superoxide Anion Generation Optic Nerve Development Magnesium Ion Homeostasis Negative Regulation Of B Cell Proliferation Metal Ion Homeostasis Cellular Response To Estradiol Stimulus Protein Insertion Into Membrane Astrocyte Development Anatomical Structure Arrangement Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Synaptic Transmission, Glutamatergic Positive Regulation Of Viral Genome Replication Single Organismal Cell-cell Adhesion Regulation Of Dopamine Secretion Regulation Of Catenin Import Into Nucleus Cellular Response To Epidermal Growth Factor Stimulus Ion Homeostasis Response To Epidermal Growth Factor Cellular Response To Estrogen Stimulus Neuronal Action Potential Regulation Of MAPK Cascade Cellular Response To Dexamethasone Stimulus Positive Regulation Of Vasoconstriction Positive Regulation Of Vasodilation Hydrogen Peroxide Metabolic Process
Tagcloud ?		abca1 adamtsl3 aiming apc crc elac1 epha3 ephb6 ercc6 excluding exome fbxw7 germline kbiosciences marginal mll3 obscn recessive rs4987622 rs6464211 rs6947538 silico smad4 snps somatic spite strongest syne1 trpv6
Tagcloud (Difference) ?		abca1 adamtsl3 aiming apc crc elac1 epha3 ephb6 ercc6 excluding exome fbxw7 germline kbiosciences marginal mll3 obscn recessive rs4987622 rs6464211 rs6947538 silico smad4 snps somatic spite strongest syne1 trpv6
Tagcloud (Intersection) ?