PIGH and PIGA

Number of citations of the paper that reports this interaction (PMID 9463366)
39

Data Source:
HPRD (in vitro, in vivo)

		PIGH	PIGA
Gene Name		phosphatidylinositol glycan anchor biosynthesis, class H	phosphatidylinositol glycan anchor biosynthesis, class A
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) Complex Endoplasmic Reticulum Endoplasmic Reticulum Membrane	Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) Complex Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	Catalytic Activity Phosphatidylinositol N-acetylglucosaminyltransferase Activity	Protein Binding UDP-glycosyltransferase Activity Phosphatidylinositol N-acetylglucosaminyltransferase Activity
	Biological Process	Cellular Protein Modification Process C-terminal Protein Lipidation GPI Anchor Biosynthetic Process Preassembly Of GPI Anchor In ER Membrane Post-translational Protein Modification Cellular Protein Metabolic Process	C-terminal Protein Lipidation GPI Anchor Biosynthetic Process Positive Regulation Of Metabolic Process Preassembly Of GPI Anchor In ER Membrane Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		Synthesis of glycosylphosphatidylinositol (GPI) Post-translational protein modification Post-translational modification: synthesis of GPI-anchored proteins	Synthesis of glycosylphosphatidylinositol (GPI) Post-translational protein modification Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: PIGA PIGQ VKORC1	4 interactors: DPM2 PIGH PIGQ PIGY
Entrez ID		5283	5277
HPRD ID		02540	02410
Ensembl ID		ENSG00000100564	ENSG00000165195
Uniprot IDs		H0YLY9 Q14442	P37287
PDB IDs
Enriched GO Terms of Interacting Partners?		Post-translational Protein Modification Preassembly Of GPI Anchor In ER Membrane C-terminal Protein Lipidation GPI Anchor Biosynthetic Process GPI Anchor Metabolic Process Glycolipid Biosynthetic Process Protein Lipidation Lipoprotein Biosynthetic Process Phosphatidylinositol Biosynthetic Process Glycolipid Metabolic Process Lipoprotein Metabolic Process Glycerophospholipid Biosynthetic Process Phosphatidylinositol Metabolic Process Membrane Lipid Metabolic Process Phospholipid Biosynthetic Process Glycerophospholipid Metabolic Process Glycerolipid Metabolic Process Phospholipid Metabolic Process Vitamin K Metabolic Process Lipid Biosynthetic Process Peptidyl-glutamic Acid Carboxylation Cellular Protein Modification Process Quinone Metabolic Process Cellular Lipid Metabolic Process Drug Metabolic Process Organophosphate Metabolic Process Cellular Protein Metabolic Process Lipid Metabolic Process Cellular Ketone Metabolic Process Protein Metabolic Process Vitamin Metabolic Process Bone Development	GPI Anchor Biosynthetic Process GPI Anchor Metabolic Process Glycolipid Biosynthetic Process Protein Lipidation Lipoprotein Biosynthetic Process Phosphatidylinositol Biosynthetic Process Preassembly Of GPI Anchor In ER Membrane Glycolipid Metabolic Process Lipoprotein Metabolic Process Glycerophospholipid Biosynthetic Process C-terminal Protein Lipidation Phosphatidylinositol Metabolic Process Membrane Lipid Metabolic Process Phospholipid Biosynthetic Process Glycerophospholipid Metabolic Process Glycerolipid Metabolic Process Phospholipid Metabolic Process Lipid Biosynthetic Process Post-translational Protein Modification Cellular Lipid Metabolic Process Organophosphate Metabolic Process Lipid Metabolic Process Phosphate-containing Compound Metabolic Process Cellular Protein Modification Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Dolichol Metabolic Process Cellular Protein Metabolic Process Biosynthetic Process Protein O-linked Mannosylation Protein Mannosylation Protein Metabolic Process Mannosylation Dolichol-linked Oligosaccharide Biosynthetic Process Carbohydrate Metabolic Process Protein O-linked Glycosylation Protein N-linked Glycosylation Via Asparagine Protein N-linked Glycosylation Isoprenoid Metabolic Process Regulation Of Protein Stability Cellular Metabolic Process
Tagcloud ?			adenoids belonging defense degranulation destructive dimers eosinophils extravasation glandular helper ige immunopathology leukocytes migrate mucosa penetrating perhaps pigr polymers priming reaches secretions secretory th2 tonsils transported unsuccessful
Tagcloud (Difference) ?			adenoids belonging defense degranulation destructive dimers eosinophils extravasation glandular helper ige immunopathology leukocytes migrate mucosa penetrating perhaps pigr polymers priming reaches secretions secretory th2 tonsils transported unsuccessful
Tagcloud (Intersection) ?