PIGA and PIGY

Number of citations of the paper that reports this interaction (PMID 16162815)
10

Data Source:
HPRD (in vivo)

		PIGA	PIGY
Gene Name		phosphatidylinositol glycan anchor biosynthesis, class A	phosphatidylinositol glycan anchor biosynthesis, class Y
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) Complex Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane	Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) Complex Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding UDP-glycosyltransferase Activity Phosphatidylinositol N-acetylglucosaminyltransferase Activity
	Biological Process	C-terminal Protein Lipidation GPI Anchor Biosynthetic Process Positive Regulation Of Metabolic Process Preassembly Of GPI Anchor In ER Membrane Post-translational Protein Modification Cellular Protein Metabolic Process	GPI Anchor Biosynthetic Process
Pathways		Synthesis of glycosylphosphatidylinositol (GPI) Post-translational protein modification Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS			Bipolar disorder ( 22925353)
Protein-Protein Interactions		4 interactors: DPM2 PIGH PIGQ PIGY	2 interactors: ABCB4 PIGA
Entrez ID		5277	84992
HPRD ID		02410	17492
Ensembl ID		ENSG00000165195
Uniprot IDs		P37287	Q3MUY2
PDB IDs
Enriched GO Terms of Interacting Partners?		GPI Anchor Biosynthetic Process GPI Anchor Metabolic Process Glycolipid Biosynthetic Process Protein Lipidation Lipoprotein Biosynthetic Process Phosphatidylinositol Biosynthetic Process Preassembly Of GPI Anchor In ER Membrane Glycolipid Metabolic Process Lipoprotein Metabolic Process Glycerophospholipid Biosynthetic Process C-terminal Protein Lipidation Phosphatidylinositol Metabolic Process Membrane Lipid Metabolic Process Phospholipid Biosynthetic Process Glycerophospholipid Metabolic Process Glycerolipid Metabolic Process Phospholipid Metabolic Process Lipid Biosynthetic Process Post-translational Protein Modification Cellular Lipid Metabolic Process Organophosphate Metabolic Process Lipid Metabolic Process Phosphate-containing Compound Metabolic Process Cellular Protein Modification Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Dolichol Metabolic Process Cellular Protein Metabolic Process Biosynthetic Process Protein O-linked Mannosylation Protein Mannosylation Protein Metabolic Process Mannosylation Dolichol-linked Oligosaccharide Biosynthetic Process Carbohydrate Metabolic Process Protein O-linked Glycosylation Protein N-linked Glycosylation Via Asparagine Protein N-linked Glycosylation Isoprenoid Metabolic Process Regulation Of Protein Stability Cellular Metabolic Process	Xenobiotic Transport Preassembly Of GPI Anchor In ER Membrane Cellular Lipid Metabolic Process C-terminal Protein Lipidation Drug Transmembrane Transport Lipid Metabolic Process Drug Transport GPI Anchor Biosynthetic Process GPI Anchor Metabolic Process Glycolipid Biosynthetic Process Protein Lipidation Lipoprotein Biosynthetic Process Phosphatidylinositol Biosynthetic Process Glycolipid Metabolic Process Lipoprotein Metabolic Process Glycerophospholipid Biosynthetic Process Post-translational Protein Modification Phosphatidylinositol Metabolic Process Membrane Lipid Metabolic Process Phospholipid Biosynthetic Process
Tagcloud ?		adenoids belonging defense degranulation destructive dimers eosinophils extravasation glandular helper ige immunopathology leukocytes migrate mucosa penetrating perhaps pigr polymers priming reaches secretions secretory th2 tonsils transported unsuccessful
Tagcloud (Difference) ?		adenoids belonging defense degranulation destructive dimers eosinophils extravasation glandular helper ige immunopathology leukocytes migrate mucosa penetrating perhaps pigr polymers priming reaches secretions secretory th2 tonsils transported unsuccessful
Tagcloud (Intersection) ?