PIGH and PIGQ

Number of citations of the paper that reports this interaction (PMID 9463366)
39

Data Source:
HPRD (in vitro)

		PIGH	PIGQ
Gene Name		phosphatidylinositol glycan anchor biosynthesis, class H	phosphatidylinositol glycan anchor biosynthesis, class Q
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) Complex Endoplasmic Reticulum Endoplasmic Reticulum Membrane	Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) Complex Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Catalytic Activity Phosphatidylinositol N-acetylglucosaminyltransferase Activity	Phosphatidylinositol N-acetylglucosaminyltransferase Activity
	Biological Process	Cellular Protein Modification Process C-terminal Protein Lipidation GPI Anchor Biosynthetic Process Preassembly Of GPI Anchor In ER Membrane Post-translational Protein Modification Cellular Protein Metabolic Process	Carbohydrate Metabolic Process C-terminal Protein Lipidation Preassembly Of GPI Anchor In ER Membrane Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		Synthesis of glycosylphosphatidylinositol (GPI) Post-translational protein modification Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS			Disc degeneration (lumbar) ( 22993228)
Protein-Protein Interactions		3 interactors: PIGA PIGQ VKORC1	4 interactors: PIGA PIGC PIGH SMAD1
Entrez ID		5283	9091
HPRD ID		02540	09307
Ensembl ID		ENSG00000100564	ENSG00000007541
Uniprot IDs		H0YLY9 Q14442	B2RAU6 Q9BRB3
PDB IDs
Enriched GO Terms of Interacting Partners?		Post-translational Protein Modification Preassembly Of GPI Anchor In ER Membrane C-terminal Protein Lipidation GPI Anchor Biosynthetic Process GPI Anchor Metabolic Process Glycolipid Biosynthetic Process Protein Lipidation Lipoprotein Biosynthetic Process Phosphatidylinositol Biosynthetic Process Glycolipid Metabolic Process Lipoprotein Metabolic Process Glycerophospholipid Biosynthetic Process Phosphatidylinositol Metabolic Process Membrane Lipid Metabolic Process Phospholipid Biosynthetic Process Glycerophospholipid Metabolic Process Glycerolipid Metabolic Process Phospholipid Metabolic Process Vitamin K Metabolic Process Lipid Biosynthetic Process Peptidyl-glutamic Acid Carboxylation Cellular Protein Modification Process Quinone Metabolic Process Cellular Lipid Metabolic Process Drug Metabolic Process Organophosphate Metabolic Process Cellular Protein Metabolic Process Lipid Metabolic Process Cellular Ketone Metabolic Process Protein Metabolic Process Vitamin Metabolic Process Bone Development	Preassembly Of GPI Anchor In ER Membrane C-terminal Protein Lipidation GPI Anchor Biosynthetic Process GPI Anchor Metabolic Process Glycolipid Biosynthetic Process Protein Lipidation Lipoprotein Biosynthetic Process Phosphatidylinositol Biosynthetic Process Glycolipid Metabolic Process Lipoprotein Metabolic Process Glycerophospholipid Biosynthetic Process Post-translational Protein Modification Phosphatidylinositol Metabolic Process Membrane Lipid Metabolic Process Phospholipid Biosynthetic Process Glycerophospholipid Metabolic Process Glycerolipid Metabolic Process Phospholipid Metabolic Process Lipid Biosynthetic Process Phosphate-containing Compound Metabolic Process Cellular Lipid Metabolic Process Organophosphate Metabolic Process Cellular Protein Modification Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Lipid Metabolic Process Primary MiRNA Processing Cellular Protein Metabolic Process Osteoblast Fate Commitment Biosynthetic Process SMAD Protein Complex Assembly Mesodermal Cell Fate Commitment Protein Metabolic Process Cardiac Muscle Cell Proliferation Production Of MiRNAs Involved In Gene Silencing By MiRNA Cellular Response To BMP Stimulus Mesodermal Cell Differentiation Cell Fate Commitment Involved In Formation Of Primary Germ Layer Cardiac Muscle Tissue Growth Negative Regulation Of Muscle Cell Apoptotic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus Positive Regulation Of Dendrite Morphogenesis Gene Silencing By MiRNA Cellular Response To DsRNA Positive Regulation Of Cartilage Development Posttranscriptional Gene Silencing Regulation Of Muscle Cell Apoptotic Process Positive Regulation Of Dendrite Development Gene Silencing By RNA Regulation Of Dendrite Morphogenesis
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