PIGA and PIGQ

Number of citations of the paper that reports this interaction (PMID 9463366)
39

Data Source:
HPRD (in vitro)

		PIGA	PIGQ
Gene Name		phosphatidylinositol glycan anchor biosynthesis, class A	phosphatidylinositol glycan anchor biosynthesis, class Q
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) Complex Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane	Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) Complex Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding UDP-glycosyltransferase Activity Phosphatidylinositol N-acetylglucosaminyltransferase Activity	Phosphatidylinositol N-acetylglucosaminyltransferase Activity
	Biological Process	C-terminal Protein Lipidation GPI Anchor Biosynthetic Process Positive Regulation Of Metabolic Process Preassembly Of GPI Anchor In ER Membrane Post-translational Protein Modification Cellular Protein Metabolic Process	Carbohydrate Metabolic Process C-terminal Protein Lipidation Preassembly Of GPI Anchor In ER Membrane Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		Synthesis of glycosylphosphatidylinositol (GPI) Post-translational protein modification Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS			Disc degeneration (lumbar) ( 22993228)
Protein-Protein Interactions		4 interactors: DPM2 PIGH PIGQ PIGY	4 interactors: PIGA PIGC PIGH SMAD1
Entrez ID		5277	9091
HPRD ID		02410	09307
Ensembl ID		ENSG00000165195	ENSG00000007541
Uniprot IDs		P37287	B2RAU6 Q9BRB3
PDB IDs
Enriched GO Terms of Interacting Partners?		GPI Anchor Biosynthetic Process GPI Anchor Metabolic Process Glycolipid Biosynthetic Process Protein Lipidation Lipoprotein Biosynthetic Process Phosphatidylinositol Biosynthetic Process Preassembly Of GPI Anchor In ER Membrane Glycolipid Metabolic Process Lipoprotein Metabolic Process Glycerophospholipid Biosynthetic Process C-terminal Protein Lipidation Phosphatidylinositol Metabolic Process Membrane Lipid Metabolic Process Phospholipid Biosynthetic Process Glycerophospholipid Metabolic Process Glycerolipid Metabolic Process Phospholipid Metabolic Process Lipid Biosynthetic Process Post-translational Protein Modification Cellular Lipid Metabolic Process Organophosphate Metabolic Process Lipid Metabolic Process Phosphate-containing Compound Metabolic Process Cellular Protein Modification Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Dolichol Metabolic Process Cellular Protein Metabolic Process Biosynthetic Process Protein O-linked Mannosylation Protein Mannosylation Protein Metabolic Process Mannosylation Dolichol-linked Oligosaccharide Biosynthetic Process Carbohydrate Metabolic Process Protein O-linked Glycosylation Protein N-linked Glycosylation Via Asparagine Protein N-linked Glycosylation Isoprenoid Metabolic Process Regulation Of Protein Stability Cellular Metabolic Process	Preassembly Of GPI Anchor In ER Membrane C-terminal Protein Lipidation GPI Anchor Biosynthetic Process GPI Anchor Metabolic Process Glycolipid Biosynthetic Process Protein Lipidation Lipoprotein Biosynthetic Process Phosphatidylinositol Biosynthetic Process Glycolipid Metabolic Process Lipoprotein Metabolic Process Glycerophospholipid Biosynthetic Process Post-translational Protein Modification Phosphatidylinositol Metabolic Process Membrane Lipid Metabolic Process Phospholipid Biosynthetic Process Glycerophospholipid Metabolic Process Glycerolipid Metabolic Process Phospholipid Metabolic Process Lipid Biosynthetic Process Phosphate-containing Compound Metabolic Process Cellular Lipid Metabolic Process Organophosphate Metabolic Process Cellular Protein Modification Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Lipid Metabolic Process Primary MiRNA Processing Cellular Protein Metabolic Process Osteoblast Fate Commitment Biosynthetic Process SMAD Protein Complex Assembly Mesodermal Cell Fate Commitment Protein Metabolic Process Cardiac Muscle Cell Proliferation Production Of MiRNAs Involved In Gene Silencing By MiRNA Cellular Response To BMP Stimulus Mesodermal Cell Differentiation Cell Fate Commitment Involved In Formation Of Primary Germ Layer Cardiac Muscle Tissue Growth Negative Regulation Of Muscle Cell Apoptotic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus Positive Regulation Of Dendrite Morphogenesis Gene Silencing By MiRNA Cellular Response To DsRNA Positive Regulation Of Cartilage Development Posttranscriptional Gene Silencing Regulation Of Muscle Cell Apoptotic Process Positive Regulation Of Dendrite Development Gene Silencing By RNA Regulation Of Dendrite Morphogenesis
Tagcloud ?		adenoids belonging defense degranulation destructive dimers eosinophils extravasation glandular helper ige immunopathology leukocytes migrate mucosa penetrating perhaps pigr polymers priming reaches secretions secretory th2 tonsils transported unsuccessful
Tagcloud (Difference) ?		adenoids belonging defense degranulation destructive dimers eosinophils extravasation glandular helper ige immunopathology leukocytes migrate mucosa penetrating perhaps pigr polymers priming reaches secretions secretory th2 tonsils transported unsuccessful
Tagcloud (Intersection) ?