PEX5L

Description		peroxisomal biogenesis factor 5 like
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Peroxisomal Membrane Cytosol Membrane Receptor Complex
	Molecular Function	Peroxisome Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding Protein Binding Small GTPase Binding
	Biological Process	Protein Import Into Peroxisome Matrix, Docking
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Childhood body mass index ( 33045005) Glucose homeostasis traits ( 25524916) LDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Midgestational circulating levels of PBDEs (fetal genetic effect) ( 28235828) Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Type 2 diabetes ( 21490949)
Interacting Genes		3 interacting genes: HCN1 PEX7 RAF1
Entrez ID		51555
HPRD ID		11425
Ensembl ID		ENSG00000114757
Uniprot IDs		Q8IYB4
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Targeting To Peroxisome Protein Import Into Peroxisome Matrix Intracellular Protein Localization Enzyme Binding Ether Lipid Biosynthetic Process Peroxisome Matrix Targeting Signal-2 Binding Type II Interferon-mediated Signaling Pathway Insulin Secretion Involved In Cellular Response To Glucose Stimulus Adenylate Cyclase Activator Activity ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway Death-inducing Signaling Complex Assembly Neurotrophin TRK Receptor Signaling Pathway Pseudopodium Retinal Cone Cell Development Apical Dendrite Negative Regulation Of Synaptic Transmission, Glutamatergic Somatodendritic Compartment Negative Regulation Of Action Potential Regulation Of Membrane Hyperpolarization Voltage-gated Sodium Channel Activity Apical Protein Localization Intracellular CAMP-activated Cation Channel Activity Involved In Regulation Of Presynaptic Membrane Potential General Adaptation Syndrome, Behavioral Process Voltage-gated Monoatomic Cation Channel Activity HCN Channel Complex Regulation Of SA Node Cell Action Potential Intracellularly CAMP-activated Cation Channel Activity Maternal Behavior Parental Behavior Positive Regulation Of Membrane Hyperpolarization Establishment Of Protein Localization To Peroxisome Type B Pancreatic Cell Proliferation Schwann Cell Development Response To L-glutamate Ether Lipid Metabolic Process Peroxisomal Membrane Transport CAMP Binding Positive Regulation Of Peptidyl-serine Phosphorylation Face Development ERBB2 Signaling Pathway MAP Kinase Kinase Kinase Activity Endochondral Ossification Intracellular Protein Transmembrane Transport Peroxisome Organization Neurotrophin Signaling Pathway Regulation Of Peptidyl-serine Phosphorylation Response To Muscle Stretch Thyroid Gland Development Sodium Ion Import Across Plasma Membrane
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