CWC15 and RBM17

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, two hybrid)

		CWC15	RBM17
Gene Name		CWC15 spliceosome-associated protein	RNA binding motif protein 17
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Catalytic Step 2 Spliceosome	Nucleoplasm Spliceosomal Complex
	Molecular Function	RNA Binding Protein Binding	Nucleotide Binding RNA Binding Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome RNA Splicing Gene Expression	Alternative MRNA Splicing, Via Spliceosome
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder and conduct disorder ( 18951430)	Vitiligo ( 20410501)
Protein-Protein Interactions		5 interactors: APP CTNNBL1 PRNP RBM17 SGCE	17 interactors: APBB1 CCHCR1 CEP55 CSNK2A1 CWC15 DHX15 FAM9B GOLGA2 HINFP KIAA1683 PPP1R12C QRICH1 SAP30BP SAT1 SF1 SF3B1 U2SURP
Entrez ID		51503	84991
HPRD ID		13703	09501
Ensembl ID		ENSG00000150316	ENSG00000134453
Uniprot IDs		Q9P013	Q5W009 Q96I25
PDB IDs			2PE8 2PEH
Enriched GO Terms of Interacting Partners?		Cellular Copper Ion Homeostasis Copper Ion Homeostasis MRNA Processing MRNA Metabolic Process RNA Processing Transition Metal Ion Homeostasis Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Negative Regulation Of Calcineurin-NFAT Signaling Cascade MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Cellular Response To Copper Ion Learning Or Memory Axon Choice Point Recognition Negative Regulation Of Calcium-mediated Signaling Cognition Neuron Remodeling Negative Regulation Of Interleukin-17 Production RNA Splicing Regulation Of Calcineurin-NFAT Signaling Cascade Negative Regulation Of Activated T Cell Proliferation Axon Guidance Cellular Metal Ion Homeostasis Response To Oxidative Stress Alternative MRNA Splicing, Via Spliceosome Cellular Cation Homeostasis Single-organism Behavior Cellular Ion Homeostasis Metal Ion Homeostasis Negative Regulation Of Interleukin-2 Production Negative Regulation Of T Cell Receptor Signaling Pathway System Development Response To Copper Ion Suckling Behavior Axonogenesis Cellular Chemical Homeostasis Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Ion Homeostasis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Behavior Chemotaxis Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Multicellular Organismal Development Neuron Projection Morphogenesis	MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Processing RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process RNA Splicing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process MRNA Processing Nitrogen Compound Metabolic Process MRNA Metabolic Process Negative Regulation Of Thymidylate Synthase Biosynthetic Process Cell Cycle Mitotic Cell Cycle Spermidine Acetylation Putrescine Catabolic Process Primary Sex Determination Cell Cycle Process Oxalate Transport MRNA 3'-splice Site Recognition Polyamine Catabolic Process 3'-phosphoadenosine 5'-phosphosulfate Biosynthetic Process Negative Regulation Of Female Gonad Development
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