TRIAP1 and AMY2A

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		TRIAP1	AMY2A
Gene Name		TP53 regulated inhibitor of apoptosis 1	amylase, alpha 2A (pancreatic)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Intermembrane Space Protein Complex Perinuclear Region Of Cytoplasm	Extracellular Region Extracellular Space Extracellular Vesicular Exosome
	Molecular Function	P53 Binding Protein Binding Phosphatidic Acid Transporter Activity	Alpha-amylase Activity Calcium Ion Binding Chloride Ion Binding
	Biological Process	DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Phospholipid Transport DNA Damage Response, Signal Transduction By P53 Class Mediator Cellular Response To UV Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Release Of Cytochrome C From Mitochondria Regulation Of Membrane Lipid Distribution Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Phospholipid Transport	Carbohydrate Metabolic Process Pathogenesis Carbohydrate Catabolic Process Polysaccharide Digestion Small Molecule Metabolic Process
Pathways			Myoclonic epilepsy of Lafora Digestion of dietary carbohydrate Glycogen storage diseases Metabolism of carbohydrates
Drugs
Diseases
GWAS		Insulin resistance/response ( 21901158)
Protein-Protein Interactions		4 interactors: AMY2A APAF1 HSPA1A TP53	3 interactors: GP2 IGF1R TRIAP1
Entrez ID		51499	279
HPRD ID		13698	00094
Ensembl ID		ENSG00000170855	ENSG00000243480
Uniprot IDs		O43715	P04746
PDB IDs			1B2Y 1BSI 1CPU 1HNY 1KB3 1KBB 1KBK 1KGU 1KGW 1KGX 1U2Y 1U30 1U33 1XCW 1XCX 1XD0 1XD1 1XGZ 1XH0 1XH1 1XH2 2CPU 2QMK 2QV4 3BAI 3BAJ 3BAK 3BAW 3BAX 3BAY 3CPU 3IJ7 3IJ8 3IJ9 3OLD 3OLE 3OLG 3OLI 4GQQ 4GQR
Enriched GO Terms of Interacting Partners?		Neuron Apoptotic Process Neuron Death Response To Biotic Stimulus Response To G1 DNA Damage Checkpoint Signaling Negative Regulation Of Cell Growth Negative Regulation Of Macromitophagy Cellular Heat Acclimation Oligodendrocyte Apoptotic Process Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Cellular Response To Oxidative Stress Negative Regulation Of Helicase Activity Negative Regulation Of Growth Polysaccharide Digestion Regulation Of Apoptotic Process Positive Regulation Of Cell Aging Positive Regulation Of Thymocyte Apoptotic Process Regulation Of Cell Death Mitochondrial DNA Repair Regulation Of Mitochondrion Degradation T Cell Proliferation Involved In Immune Response B Cell Lineage Commitment Glial Cell Apoptotic Process Apoptotic Signaling Pathway Regulation Of Cell Growth Regulation Of Apoptotic DNA Fragmentation Oxidative Stress-induced Premature Senescence Negative Regulation Of Inclusion Body Assembly ER Overload Response Negative Regulation Of Macroautophagy Stress-induced Premature Senescence Response To Oxidative Stress Regulation Of Cellular Component Organization Positive Regulation Of T Cell Apoptotic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Strand Renaturation Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C Regulation Of Cellular Protein Metabolic Process DNA Damage Response, Signal Transduction Resulting In Transcription Mitotic Cell Cycle Arrest Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Regulation Of Thymocyte Apoptotic Process Replicative Senescence Positive Regulation Of Mitochondrial Membrane Permeability Determination Of Adult Lifespan Positive Regulation Of Lymphocyte Apoptotic Process Circadian Behavior Regulation Of Protein Metabolic Process Regulation Of Inclusion Body Assembly Mitochondrial DNA Metabolic Process	Inactivation Of MAPKK Activity Antigen Transcytosis By M Cells In Mucosal-associated Lymphoid Tissue Positive Regulation Of Cell Cycle Process Positive Regulation Of Cell Cycle Regulation Of Mitotic Cell Cycle Positive Regulation Of Steroid Hormone Biosynthetic Process Exocrine Pancreas Development Negative Regulation Of Intracellular Signal Transduction Positive Regulation Of Phospholipid Transport Positive Regulation Of Hormone Biosynthetic Process Regulation Of Cell Cycle Process Transcytosis Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Male Sex Determination Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Negative Regulation Of Release Of Cytochrome C From Mitochondria Response To Vitamin E Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Phosphatidylinositol 3-kinase Signaling Negative Regulation Of Signal Transduction By P53 Class Mediator Sex Determination Regulation Of Hormone Biosynthetic Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Steroid Metabolic Process Negative Regulation Of Catalytic Activity Negative Regulation Of Cellular Protein Metabolic Process Mucosal Immune Response Negative Regulation Of Mitochondrion Organization Regulation Of Hormone Metabolic Process Negative Regulation Of Protein Metabolic Process Negative Regulation Of Muscle Cell Apoptotic Process Negative Regulation Of Apoptotic Process Regulation Of Organelle Organization Negative Regulation Of Programmed Cell Death Regulation Of Cell Cycle Peptidyl-tyrosine Autophosphorylation Negative Regulation Of Protein Kinase B Signaling Positive Regulation Of Cytokinesis Prostate Gland Epithelium Morphogenesis Positive Regulation Of Mitotic Nuclear Division Negative Regulation Of Cell Death Prostate Gland Morphogenesis Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Signal Transduction Regulation Of Muscle Cell Apoptotic Process Regulation Of Cytokinesis DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Negative Regulation Of Signaling Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint
Tagcloud ?		cardiolipin cl conferred cytochrome ensures excess exert exogenously extrinsic facilitates glycerophospholipid highlight impairs ims inner intermembrane intrinsic mitochondria mitochondrial orchestrates p53csv pa phosphatidic phosphatidylglycerol preli renders space supply vulnerable
Tagcloud (Difference) ?		cardiolipin cl conferred cytochrome ensures excess exert exogenously extrinsic facilitates glycerophospholipid highlight impairs ims inner intermembrane intrinsic mitochondria mitochondrial orchestrates p53csv pa phosphatidic phosphatidylglycerol preli renders space supply vulnerable
Tagcloud (Intersection) ?