TRIAP1

Gene Name		TP53 regulated inhibitor of apoptosis 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Intermembrane Space Protein Complex Perinuclear Region Of Cytoplasm
	Molecular Function	P53 Binding Protein Binding Phosphatidic Acid Transporter Activity
	Biological Process	DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Phospholipid Transport DNA Damage Response, Signal Transduction By P53 Class Mediator Cellular Response To UV Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Release Of Cytochrome C From Mitochondria Regulation Of Membrane Lipid Distribution Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Phospholipid Transport
Pathways
Drugs
Diseases
GWAS		Insulin resistance/response ( 21901158)
Protein-protein Interactions		4 interactors: AMY2A APAF1 HSPA1A TP53
Entrez ID		51499
HPRD ID		13698
Ensembl ID		ENSG00000170855
Uniprot IDs		O43715
PDB IDs
Enriched GO Terms of Interacting Partners?		Neuron Apoptotic Process Neuron Death Response To Biotic Stimulus Response To G1 DNA Damage Checkpoint Signaling Negative Regulation Of Cell Growth Negative Regulation Of Macromitophagy Cellular Heat Acclimation Oligodendrocyte Apoptotic Process Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Cellular Response To Oxidative Stress Negative Regulation Of Helicase Activity Negative Regulation Of Growth Polysaccharide Digestion Regulation Of Apoptotic Process Positive Regulation Of Cell Aging Positive Regulation Of Thymocyte Apoptotic Process Regulation Of Cell Death Mitochondrial DNA Repair Regulation Of Mitochondrion Degradation T Cell Proliferation Involved In Immune Response B Cell Lineage Commitment Glial Cell Apoptotic Process Apoptotic Signaling Pathway Regulation Of Cell Growth Regulation Of Apoptotic DNA Fragmentation Oxidative Stress-induced Premature Senescence Negative Regulation Of Inclusion Body Assembly ER Overload Response Negative Regulation Of Macroautophagy Stress-induced Premature Senescence Response To Oxidative Stress Regulation Of Cellular Component Organization Positive Regulation Of T Cell Apoptotic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Strand Renaturation Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C Regulation Of Cellular Protein Metabolic Process DNA Damage Response, Signal Transduction Resulting In Transcription Mitotic Cell Cycle Arrest Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Regulation Of Thymocyte Apoptotic Process Replicative Senescence Positive Regulation Of Mitochondrial Membrane Permeability Determination Of Adult Lifespan Positive Regulation Of Lymphocyte Apoptotic Process Circadian Behavior Regulation Of Protein Metabolic Process Regulation Of Inclusion Body Assembly Mitochondrial DNA Metabolic Process
Tagcloud ?		cardiolipin cl conferred cytochrome ensures excess exert exogenously extrinsic facilitates glycerophospholipid highlight impairs ims inner intermembrane intrinsic mitochondria mitochondrial orchestrates p53csv pa phosphatidic phosphatidylglycerol preli renders space supply vulnerable