ANKFY1 and RHOD

Number of citations of the paper that reports this interaction (PubMedID 24102721)
0

Data Source:
BioGRID (two hybrid)

		ANKFY1	RHOD
Description		ankyrin repeat and FYVE domain containing 1	ras homolog family member D
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosomal Membrane Endosome Early Endosome Cytosol Endosome Membrane Membrane Retromer Complex Macropinosome Extracellular Exosome	Golgi Membrane Mitochondrial Outer Membrane Endosome Early Endosome Cytosol Plasma Membrane Endosome Membrane Membrane Cell Projection
	Molecular Function	Protein Binding Zinc Ion Binding Small GTPase Binding Metal Ion Binding Phosphatidylinositol Phosphate Binding	Nucleotide Binding GTPase Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding GTP Binding Protein Kinase Binding
	Biological Process	Endocytosis Endosomal Transport Endosomal Vesicle Fusion Retrograde Transport, Endosome To Golgi Positive Regulation Of Pinocytosis Golgi To Lysosome Transport	Protein Targeting Actin Filament Organization Small GTPase-mediated Signal Transduction Rho Protein Signal Transduction Fibroblast Growth Factor Receptor Signaling Pathway Cell Projection Assembly Lamellipodium Assembly Actin Filament Polymerization Positive Regulation Of Cell Migration Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Cell Adhesion Focal Adhesion Assembly Actin Filament Bundle Assembly Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Focal Adhesion Assembly Response To Fibroblast Growth Factor
Pathways		RHOD GTPase cycle	RHO GTPases Activate Formins RHOD GTPase cycle
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30578418) Functional impairment in major depressive disorder, bipolar disorder and schizophrenia ( 24039173) Hematocrit ( 32888494) Refractive error ( 32231278) Schizophrenia x sex interaction ( 34099189)	Height ( 20881960 25282103) Hip circumference adjusted for BMI ( 34021172) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		6 interacting genes: CLK1 RAB5A RHOD RHOF SRPK2 UBC	13 interacting genes: ACVR1 ADCK5 ADRB2 ANKFY1 BMPR1B DIAPH2 HRAS IHH PLXNA1 SMAD2 SMAD4 SMURF2 TGFBR1
Entrez ID		51479	29984
HPRD ID		09717	05776
Ensembl ID		ENSG00000185722	ENSG00000173156
Uniprot IDs		B3KPZ0 Q9P2R3	E9PIG5 O00212
PDB IDs			2J1L 7KDC
Enriched GO Terms of Interacting Partners?		Nucleotide Binding GTPase Activity Endosome Membrane GTP Binding	SMAD Binding Transforming Growth Factor Beta Receptor Activity, Type I Activin Receptor Signaling Pathway Transmembrane Receptor Protein Serine/threonine Kinase Activity Cell Surface Receptor Signaling Pathway Positive Regulation Of Epithelial To Mesenchymal Transition Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Cell Fate Commitment Pattern Specification Process Positive Regulation Of Signal Transduction Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Tissue Morphogenesis I-SMAD Binding Positive Regulation Of Multicellular Organismal Process Positive Regulation Of Cell Communication Positive Regulation Of Signaling In Utero Embryonic Development Chordate Embryonic Development Transforming Growth Factor Beta Receptor Signaling Pathway Embryo Development Ending In Birth Or Egg Hatching Multicellular Organism Development Positive Regulation Of Developmental Process Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regionalization Animal Organ Morphogenesis Regulation Of Epithelial To Mesenchymal Transition Cellular Response To BMP Stimulus Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Activin Responsive Factor Complex Regulation Of Ossification Osteoblast Differentiation Ameboidal-type Cell Migration Anatomical Structure Morphogenesis Response To Growth Factor Neuron Fate Commitment Ventricular Septum Morphogenesis Positive Regulation Of SMAD Protein Signal Transduction Positive Regulation Of Bone Mineralization Enzyme-linked Receptor Protein Signaling Pathway Developmental Growth Gastrulation Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Biomineral Tissue Development Tissue Development Regulation Of Chondrocyte Differentiation Positive Regulation Of Ossification Mesoderm Development Embryonic Morphogenesis Activin Receptor Complex
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