ANKFY1 and RHOF

Number of citations of the paper that reports this interaction (PubMedID 24102721)
0

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		ANKFY1	RHOF
Description		ankyrin repeat and FYVE domain containing 1	ras homolog family member F, filopodia associated
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosomal Membrane Endosome Early Endosome Cytosol Endosome Membrane Membrane Retromer Complex Macropinosome Extracellular Exosome	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Membrane Secretory Granule Membrane Extracellular Exosome
	Molecular Function	Protein Binding Zinc Ion Binding Small GTPase Binding Metal Ion Binding Phosphatidylinositol Phosphate Binding	Nucleotide Binding GTPase Activity Guanyl-nucleotide Exchange Factor Activity GTP Binding Protein Kinase Binding
	Biological Process	Endocytosis Endosomal Transport Endosomal Vesicle Fusion Retrograde Transport, Endosome To Golgi Positive Regulation Of Pinocytosis Golgi To Lysosome Transport	Actin Filament Organization Signal Transduction Small GTPase-mediated Signal Transduction Cell Migration Regulation Of Actin Cytoskeleton Organization Regulation Of Small GTPase Mediated Signal Transduction
Pathways		RHOD GTPase cycle	Neutrophil degranulation RHOF GTPase cycle
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30578418) Functional impairment in major depressive disorder, bipolar disorder and schizophrenia ( 24039173) Hematocrit ( 32888494) Refractive error ( 32231278) Schizophrenia x sex interaction ( 34099189)	High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Mean platelet volume ( 27863252 31194788 32888494) Platelet count ( 27863252 32888494) Platelet distribution width ( 27863252 32888494) Plateletcrit ( 27863252 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 27863252 32888494)
Interacting Genes		6 interacting genes: CLK1 RAB5A RHOD RHOF SRPK2 UBC	2 interacting genes: ANKFY1 UBC
Entrez ID		51479	54509
HPRD ID		09717	15246
Ensembl ID		ENSG00000185722	ENSG00000139725
Uniprot IDs		B3KPZ0 Q9P2R3	Q9HBH0
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleotide Binding GTPase Activity Endosome Membrane GTP Binding	Endosome Membrane Protein Tag Activity Golgi To Lysosome Transport Endosomal Vesicle Fusion Positive Regulation Of Pinocytosis Macropinosome Golgi To Vacuole Transport Retromer Complex Phosphatidylinositol Phosphate Binding
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