ANKFY1 and RHOF

Number of citations of the paper that reports this interaction (PMID 24102721)
0

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		ANKFY1	RHOF
Gene Name		ankyrin repeat and FYVE domain containing 1	ras homolog family member F (in filopodia)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosomal Membrane Early Endosome Endosome Membrane Membrane Retromer Complex Macropinosome Extracellular Vesicular Exosome	Cytosol Cytoskeleton Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Rab GTPase Binding Metal Ion Binding Phosphatidylinositol Phosphate Binding	GTPase Activity GTP Binding
	Biological Process	Endocytosis Endosome Localization Endosomal Vesicle Fusion Retrograde Transport, Endosome To Golgi Positive Regulation Of Pinocytosis Golgi To Lysosome Transport	Actin Filament Organization Small GTPase Mediated Signal Transduction Metabolic Process Regulation Of Small GTPase Mediated Signal Transduction
Pathways			Rho GTPase cycle Signaling by Rho GTPases
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: EHD1 RAB5A RHOD RHOF	1 interactors: ANKFY1
Entrez ID		51479	54509
HPRD ID		09717	15246
Ensembl ID		ENSG00000185722	ENSG00000139725
Uniprot IDs		B3KPZ0 Q9P2R3	Q9HBH0
PDB IDs
Enriched GO Terms of Interacting Partners?		Small GTPase Mediated Signal Transduction Intracellular Protein Transport Endosomal Transport Positive Regulation Of Endocytic Recycling Regulation Of Endosome Size Receptor Internalization Involved In Canonical Wnt Signaling Pathway Ras Protein Signal Transduction Cellular Protein Localization Regulation Of Endocytic Recycling Protein Transport Establishment Of Protein Localization Actin Filament Organization Intracellular Transport Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Regulation Of Vesicle-mediated Transport Intracellular Signal Transduction Blood Coagulation Hemostasis Protein Localization Regulation Of Cellular Component Organization Positive Regulation Of Cholesterol Storage Positive Regulation Of Myoblast Fusion Establishment Of Localization In Cell Regulation Of Myoblast Fusion Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion Low-density Lipoprotein Particle Clearance Endocytic Recycling Regulation Of Body Fluid Levels Early Endosome To Late Endosome Transport Regulation Of Cell Migration Wound Healing Cellular Response To Nerve Growth Factor Stimulus Actin Cytoskeleton Organization Cellular Localization Regulation Of Cell Motility Actin Filament-based Process Endocytosis Positive Regulation Of Smooth Muscle Cell Migration Positive Regulation Of Myotube Differentiation Regulation Of Locomotion Positive Regulation Of Lipid Storage Regulation Of Cellular Component Movement Response To Wounding Plasma Lipoprotein Particle Clearance Regulation Of Long-term Neuronal Synaptic Plasticity Focal Adhesion Assembly Positive Regulation Of Transport	Positive Regulation Of Pinocytosis Endosomal Vesicle Fusion Golgi To Lysosome Transport Endosome Localization Golgi To Vacuole Transport Lysosomal Transport Vesicle Fusion Retrograde Transport, Endosome To Golgi Organelle Fusion Vacuolar Transport Post-Golgi Vesicle-mediated Transport Positive Regulation Of Endocytosis Membrane Fusion Regulation Of Endocytosis Endosomal Transport Vesicle Organization Golgi Vesicle Transport Regulation Of Vesicle-mediated Transport Organelle Localization
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