VGLL1 and TEAD2

Number of citations of the paper that reports this interaction (PMID 10518497)
19

Data Source:
BioGRID (two hybrid)

		VGLL1	TEAD2
Gene Name		vestigial-like family member 1	TEA domain family member 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Transcription Factor Complex
	Molecular Function	Transcription Coactivator Activity	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Protein Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Vasculogenesis Neural Tube Closure Embryonic Heart Tube Morphogenesis Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Gene Expression Notochord Development Hippo Signaling Positive Regulation Of Transcription From RNA Polymerase II Promoter Paraxial Mesoderm Development Lateral Mesoderm Development Negative Regulation Of Cell Death
Pathways			PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Generic Transcription Pathway Metabolism of lipids and lipoproteins YAP1- and WWTR1 (TAZ)-stimulated gene expression Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: TEAD1 TEAD2 TEAD3 TEAD4	6 interactors: BCL2L15 NCOA1 NEDD4 USF2 VGLL1 YAP1
Entrez ID		51442	8463
HPRD ID		06751	03432
Ensembl ID		ENSG00000102243	ENSG00000074219
Uniprot IDs		Q99990	M0R1T9 Q15562
PDB IDs			3L15
Enriched GO Terms of Interacting Partners?		Hippo Signaling Positive Regulation Of Stem Cell Maintenance Transcription Initiation From RNA Polymerase II Promoter Regulation Of Stem Cell Maintenance DNA-templated Transcription, Initiation Positive Regulation Of Stem Cell Differentiation Lateral Mesoderm Development Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Notochord Development Paraxial Mesoderm Development Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cell Development Regulation Of Transcription From RNA Polymerase II Promoter Intracellular Signal Transduction Embryonic Heart Tube Morphogenesis Embryonic Heart Tube Development Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Development Positive Regulation Of Cell Differentiation Mesoderm Development RNA Metabolic Process Mesenchyme Development Embryo Development Positive Regulation Of Metabolic Process Gene Expression Heart Morphogenesis Cellular Macromolecule Biosynthetic Process Female Pregnancy Macromolecule Biosynthetic Process Embryonic Organ Morphogenesis Regulation Of Transcription, DNA-templated Regulation Of Cell Differentiation Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Epithelial Tube Morphogenesis Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Tube Morphogenesis Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process	Carbon Catabolite Regulation Of Transcription Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus Cellular Response To Nutrient Lactation Intracellular Steroid Hormone Receptor Signaling Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Positive Regulation Of Transcription From RNA Polymerase II Promoter By Galactose Transmission Of Virus Development Involved In Symbiotic Interaction Body Fluid Secretion Regulation Of Transcription From RNA Polymerase II Promoter Late Viral Transcription Cellular Response To Radiation Regulation Of Cellular Response To Drug Mammary Gland Development Cellular Response To Nutrient Levels Regulation Of Cell Development Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Intracellular Receptor Signaling Pathway Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Mesenchyme Development Transcription, DNA-templated Regulation Of Response To Drug Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Cellular Response To Extracellular Stimulus Regulation Of RNA Metabolic Process Response To Nutrient Heart Morphogenesis RNA Biosynthetic Process Positive Regulation Of Transcription By Glucose Progesterone Receptor Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Positive Regulation Of Female Receptivity Male Mating Behavior Positive Regulation Of Stem Cell Maintenance Regulation Of Transcription By Glucose Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Glucocorticoid Receptor Signaling Pathway Contact Inhibition Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Protein Targeting To Lysosome Positive Regulation Of Transcription, DNA-templated Organ Development Negative Regulation Of Sodium Ion Transport Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Tagcloud ?		atlas bbox1 brca1 c6orf211 carcinomas coordinated dataset esr1 foxa1 foxc1 frozen gabrp gata3 hippo intronic luminal microarrays mirna occasionally prom1 seq slc6a14 sporadic structurally taz tcga tn vestigial yap	activates activating added albumin auto bovine bsa capable cleaved confirm efficiently es fbs hc2 ialphai inter lif maintenance mes nanog oct pluripotency renewal se sub yap yes
Tagcloud (Difference) ?		atlas bbox1 brca1 c6orf211 carcinomas coordinated dataset esr1 foxa1 foxc1 frozen gabrp gata3 hippo intronic luminal microarrays mirna occasionally prom1 seq slc6a14 sporadic structurally taz tcga tn vestigial	activates activating added albumin auto bovine bsa capable cleaved confirm efficiently es fbs hc2 ialphai inter lif maintenance mes nanog oct pluripotency renewal se sub yes
Tagcloud (Intersection) ?		yap