VGLL1 and TEAD3

Number of citations of the paper that reports this interaction (PMID 10518497)
19

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		VGLL1	TEAD3
Gene Name		vestigial-like family member 1	TEA domain family member 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleoplasm Transcription Factor Complex
	Molecular Function	Transcription Coactivator Activity	RNA Polymerase II Transcription Factor Binding DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Female Pregnancy Gene Expression Hippo Signaling Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Stem Cell Maintenance
Pathways			PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Generic Transcription Pathway Metabolism of lipids and lipoproteins YAP1- and WWTR1 (TAZ)-stimulated gene expression Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: TEAD1 TEAD2 TEAD3 TEAD4	13 interactors: AP4S1 CTBP2 E2F1 E2F3 KIFC2 MYH7 PHB2 PIDD1 SUMO2 VGLL1 VGLL2 WWTR1 YAP1
Entrez ID		51442	7005
HPRD ID		06751	04411
Ensembl ID		ENSG00000102243	ENSG00000007866
Uniprot IDs		Q99990	Q99594
PDB IDs
Enriched GO Terms of Interacting Partners?		Hippo Signaling Positive Regulation Of Stem Cell Maintenance Transcription Initiation From RNA Polymerase II Promoter Regulation Of Stem Cell Maintenance DNA-templated Transcription, Initiation Positive Regulation Of Stem Cell Differentiation Lateral Mesoderm Development Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Notochord Development Paraxial Mesoderm Development Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cell Development Regulation Of Transcription From RNA Polymerase II Promoter Intracellular Signal Transduction Embryonic Heart Tube Morphogenesis Embryonic Heart Tube Development Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Development Positive Regulation Of Cell Differentiation Mesoderm Development RNA Metabolic Process Mesenchyme Development Embryo Development Positive Regulation Of Metabolic Process Gene Expression Heart Morphogenesis Cellular Macromolecule Biosynthetic Process Female Pregnancy Macromolecule Biosynthetic Process Embryonic Organ Morphogenesis Regulation Of Transcription, DNA-templated Regulation Of Cell Differentiation Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Epithelial Tube Morphogenesis Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Tube Morphogenesis Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process	Transcription, DNA-templated Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Nephron Tubule Epithelial Cell Differentiation Regulation Of Epithelial Cell Differentiation Involved In Kidney Development Regulation Of Cell Proliferation Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process RNA Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of RNA Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Hippo Signaling Positive Regulation Of Metabolic Process Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process DNA-templated Transcription, Initiation Positive Regulation Of Stem Cell Differentiation Negative Regulation Of Biosynthetic Process Positive Regulation Of Cell Proliferation Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Tissue Development Organ Morphogenesis Negative Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Cellular Nitrogen Compound Metabolic Process Signal Transduction By P53 Class Mediator Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Signal Transduction Lens Fiber Cell Apoptotic Process Negative Regulation Of Transcription, DNA-templated Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Epithelial Cell Differentiation Notch Signaling Pathway Positive Regulation Of Retinoic Acid Receptor Signaling Pathway
Tagcloud ?		atlas bbox1 brca1 c6orf211 carcinomas coordinated dataset esr1 foxa1 foxc1 frozen gabrp gata3 hippo intronic luminal microarrays mirna occasionally prom1 seq slc6a14 sporadic structurally taz tcga tn vestigial yap
Tagcloud (Difference) ?		atlas bbox1 brca1 c6orf211 carcinomas coordinated dataset esr1 foxa1 foxc1 frozen gabrp gata3 hippo intronic luminal microarrays mirna occasionally prom1 seq slc6a14 sporadic structurally taz tcga tn vestigial yap
Tagcloud (Intersection) ?