HEMK1 and CHN1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		HEMK1	CHN1
Gene Name		HemK methyltransferase family member 1	chimerin 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion	Cytosol
	Molecular Function	DNA Binding N-methyltransferase Activity Protein Methyltransferase Activity	SH3/SH2 Adaptor Activity GTPase Activator Activity Metal Ion Binding Ephrin Receptor Binding
	Biological Process	DNA Methylation Protein Methylation	Small GTPase Mediated Signal Transduction Motor Neuron Axon Guidance Positive Regulation Of Signal Transduction Regulation Of Rac GTPase Activity Positive Regulation Of GTPase Activity Ephrin Receptor Signaling Pathway Regulation Of Axonogenesis Regulation Of Small GTPase Mediated Signal Transduction
Pathways			Rho GTPase cycle Signaling by Rho GTPases
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: CDC23 CHN1	12 interactors: ACVR1 BMPR1B CDK5 CDK5R1 ERBB2 GTF3C1 HEMK1 MAPK8IP2 NCK2 RAC1 RPS3A TGFBR1
Entrez ID		51409	1123
HPRD ID		13645	00319
Ensembl ID		ENSG00000114735	ENSG00000128656
Uniprot IDs		Q9Y5R4	P15882
PDB IDs			2OSA 3CXL
Enriched GO Terms of Interacting Partners?		Metaphase/anaphase Transition Of Mitotic Cell Cycle Regulation Of Exit From Mitosis Protein K11-linked Ubiquitination Regulation Of Rac GTPase Activity Mitotic Metaphase Plate Congression Metaphase Plate Congression Motor Neuron Axon Guidance Mitotic Spindle Assembly Checkpoint Regulation Of Rac Protein Signal Transduction Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Establishment Of Chromosome Localization Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition Positive Regulation Of Catalytic Activity Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Proteasomal Protein Catabolic Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Ligase Activity Mitotic Sister Chromatid Segregation Negative Regulation Of Cell Division Regulation Of Cellular Component Organization Regulation Of Chromosome Segregation Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Sister Chromatid Segregation Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Chromosome Organization Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Ephrin Receptor Signaling Pathway Negative Regulation Of Protein Ubiquitination Negative Regulation Of Protein Catabolic Process Regulation Of Mitotic Nuclear Division Regulation Of Catalytic Activity Positive Regulation Of Protein Ubiquitination Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Axonogenesis Mitotic Cell Cycle Checkpoint Protein Polyubiquitination	Cell Morphogenesis Involved In Differentiation Cell Morphogenesis Involved In Neuron Differentiation Cell Morphogenesis Peptidyl-threonine Phosphorylation Regulation Of Protein Phosphorylation Neuron Projection Morphogenesis Neuron Differentiation Axon Guidance Positive Regulation Of Protein Phosphorylation Cell Development Locomotion Regulation Of Kinase Activity Regulation Of Phosphorylation Neuron Projection Development Cell Projection Morphogenesis Positive Regulation Of Phosphorylation Cell Part Morphogenesis Positive Regulation Of Kinase Activity Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Modification Process Regulation Of Phosphorus Metabolic Process Movement Of Cell Or Subcellular Component Axonogenesis Neuron Development Generation Of Neurons Positive Regulation Of Transferase Activity Signal Transduction By Phosphorylation Axon Development Cell Differentiation Anatomical Structure Morphogenesis Chemotaxis Neurogenesis Positive Regulation Of Cellular Protein Metabolic Process Cell Projection Organization Positive Regulation Of Protein Metabolic Process Regulation Of Signal Transduction Regulation Of Protein Kinase Activity Positive Regulation Of Signal Transduction Regulation Of Cellular Protein Metabolic Process Cell Migration Regulation Of Signaling Regulation Of Protein Metabolic Process Regulation Of Apoptotic Process Positive Regulation Of Protein Kinase Activity Serine Phosphorylation Of STAT3 Protein Cell Motility Nervous System Development Regulation Of Cell Death Serine Phosphorylation Of STAT Protein Regulation Of Cell Differentiation
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