AIG1 and SAR1A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		AIG1	SAR1A
Description		androgen induced 1	secretion associated Ras related GTPase 1A
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Endomembrane System Membrane	Cytoplasm Lysosome Lysosomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Membrane COPII Vesicle Coat Golgi Cisterna Membrane Endoplasmic Reticulum Exit Site
	Molecular Function	Protein Binding Hydrolase Activity	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity Amino Acid Sensor Activity
	Biological Process	Lipid Metabolic Process Long-chain Fatty Acid Catabolic Process	Regulation Of COPII Vesicle Coating Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport Vesicle Organization Vesicle-mediated Transport Lipoprotein Transport COPII Vesicle Coating Membrane Organization COPII-coated Vesicle Cargo Loading Regulation Of TORC1 Signaling Negative Regulation Of TORC1 Signaling Cellular Response To Leucine Starvation
Pathways
Drugs
Diseases
GWAS		Acute lymphoblastic leukemia (childhood) ( 22076464) Carotid intima media thickness ( 30510157) Daytime sleep phenotypes ( 27126917) Diffusing capacity of carbon monoxide ( 30694715) Pulse pressure ( 27841878 30578418)
Interacting Genes		54 interacting genes: APOD APOL2 AQP6 AQP9 ARL13B ASGR2 BCL2L13 BIK CCR9 CD53 CISD2 CLDN7 CPLX4 CYB5R3 CYBC1 ERGIC3 FAM209A FNDC9 FZD7 GLP1R GOLM1 GPR152 GPR35 GPX8 HIBADH HSD17B13 IER3IP1 KCNJ6 KIR2DL3 LAPTM5 LEUTX LIME1 LMNA LYVE1 MC4R MFF MRM3 PDZK1IP1 PSCA RCHY1 SAR1A SEC22B SLC10A6 SLC34A2 SLC7A14 STOM STX1A THAP4 THBD TMEM106C TMEM80 TMX2 VAMP3 VAPB	92 interacting genes: ADGRE2 AIG1 ALG8 APP AQP1 AQP10 AQP3 ASGR1 ATXN1 BCL2L2 BET1 C14orf180 C3orf52 CD53 CD81 CDS2 CEBPA CES1 CLDN19 CLDND2 CLEC7A CMTM5 CNIH1 COL4A5 CTSA CXCL16 EMP3 ERG28 FA2H FAM3C GJB2 GOLT1B GRM2 GYPA HMOX1 HMOX2 IGFBP5 JAGN1 KLHL40 LAT LHFPL5 MARCHF5 MIP MOSPD3 NAT8 NRM OLFM4 ORMDL1 ORMDL2 PEX16 PLLP PLN PLP2 PMP22 RHOT2 RMDN2 RTP2 SEC22A SELENOK SERP1 SLC30A3 SLC35A1 SLC38A7 SMIM1 SNAP47 STATH STX7 STX8 SYNGR1 TECR TMEM107 TMEM109 TMEM147 TMEM14A TMEM14C TMEM187 TMEM218 TMEM243 TMEM254 TMEM267 TMEM42 TMEM97 TRAF3 TRAM1L1 TTPA UBIAD1 UNC50 UPK1B VAMP3 VAMP4 VAMP5 VTI1B
Entrez ID		51390	56681
HPRD ID		16346	07608
Ensembl ID		ENSG00000146416	ENSG00000079332
Uniprot IDs		A0A2R8YCJ8 Q5THU2 Q9NVV5	Q5SQT9 Q9NR31
PDB IDs			2GAO 8DZM 8DZN 8DZO 8DZT 8E0H
Enriched GO Terms of Interacting Partners?		Membrane Golgi Vesicle Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Plasma Membrane	Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane SNAP Receptor Activity SNARE Complex Protein Binding Water Channel Activity Channel Activity Glycerol Transmembrane Transport Chloride Channel Inhibitor Activity Organelle Fusion Water Transport Membrane Organization Polyol Transmembrane Transport Cellular Localization Vesicle Fusion Organelle Membrane Fusion Membrane Fusion Heme Oxidation Heme Oxygenase (decyclizing) Activity Presynaptic Endosome Membrane Fluid Transport Vesicle-mediated Transport Vesicle Organization Endomembrane System Immunological Synapse Membrane Docking Plasma Membrane Establishment Of Protein Localization To Membrane Establishment Of Localization In Cell Compact Myelin Transport Vesicle Glycerol Channel Activity Intracellular Sphingolipid Homeostasis Negative Regulation Of Ceramide Biosynthetic Process Vesicle Docking One-carbon Compound Transport Renal Water Absorption Urea Transmembrane Transporter Activity Gap Junction-mediated Intercellular Transport Establishment Of Protein Localization Negative Regulation Of Sphingolipid Biosynthetic Process Granulocyte Differentiation Intracellular Transport Localization Within Membrane Ankyrin-1 Complex Vesicle Fusion With Golgi Apparatus Serine Palmitoyltransferase Complex Positive Regulation Of Chemokine Production Chemical Homeostasis
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