PBDC1 and STRN4

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		PBDC1	STRN4
Description		polysaccharide biosynthesis domain containing 1	striatin 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytoplasm Dendrite Protein-containing Complex Neuronal Cell Body Dendritic Spine FAR/SIN/STRIPAK Complex Postsynapse Glutamatergic Synapse GABA-ergic Synapse
	Molecular Function	Protein Binding	Protein Binding Calmodulin Binding Protein Domain Specific Binding Protein-macromolecule Adaptor Activity Protein-containing Complex Binding Protein Phosphatase 2A Binding Armadillo Repeat Domain Binding
	Biological Process		Negative Regulation Of Hippo Signaling Regulation Of Modification Of Postsynaptic Structure
Pathways
Drugs
Diseases
GWAS		Potassium levels ( 29403010)	Aspartate aminotransferase levels ( 33547301) Chronic lymphocytic leukemia ( 18758461 28165464) Primary sclerosing cholangitis ( 23603763)
Interacting Genes		3 interacting genes: CFTR PPP1R16A STRN4	28 interacting genes: AK5 ASNS CALM1 CAV1 CLDN12 CRK DDX39B DFFA ECSIT GDF9 JUN KLHDC2 MAP4K1 MAP4K2 MAP4K3 MAP4K4 MIF MSANTD2 MTG1 NBEA PBDC1 PI4KA PLPPR3 PPBP SLC25A6 TNIK WIPI2 WNT7A
Entrez ID		51260	29888
HPRD ID		06659	18125
Ensembl ID		ENSG00000102390	ENSG00000090372
Uniprot IDs		A6NDF3 Q9BVG4	F5GYK2 Q59GV6 Q9NRL3
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of Enamel Mineralization Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Transepithelial Water Transport Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Armadillo Repeat Domain Binding Myosin Phosphatase Regulator Activity Amelogenesis ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Regulation Of Monoatomic Anion Transport Epithelial Fluid Transport Cellular Response To Forskolin Golgi-associated Vesicle Membrane Regulation Of Modification Of Postsynaptic Structure Response To Forskolin FAR/SIN/STRIPAK Complex Chloride Transmembrane Transporter Activity Sperm Capacitation Regulation Of Modification Of Synaptic Structure Water Transport Bicarbonate Transport Negative Regulation Of Hippo Signaling Multicellular Organismal-level Water Homeostasis Protein Phosphatase 2A Binding Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Ion Transmembrane Transporter Activity Cholesterol Biosynthetic Process 14-3-3 Protein Binding Fluid Transport Protein-containing Complex Transepithelial Transport Vesicle Docking Involved In Exocytosis Positive Regulation Of Transporter Activity ABC-type Transporter Activity Protein Phosphatase Regulator Activity Sterol Biosynthetic Process Regulation Of Hippo Signaling Chloride Channel Complex Positive Regulation Of Biomineral Tissue Development Cellular Response To CAMP Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus	MAP Kinase Kinase Kinase Kinase Activity MAPK Cascade Regulation Of MAPK Cascade JNK Cascade Regulation Of JNK Cascade Intracellular Signaling Cassette Positive Regulation Of MAPK Cascade Positive Regulation Of JNK Cascade Negative Regulation Of Apoptotic Process Positive Regulation Of Intracellular Signal Transduction Kinase Activity Intracellular Signal Transduction Negative Regulation Of Programmed Cell Death Positive Regulation Of Signal Transduction Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Cellular Response To Transforming Growth Factor Beta Stimulus Nucleotide Binding ATP Binding Response To Transforming Growth Factor Beta Protein Serine Kinase Activity Protein Phosphorylation Signal Transduction Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Cell Communication Positive Regulation Of Signaling Phosphorylation Cytokine Activity Regulation Of Fibroblast Proliferation Protein Serine/threonine Kinase Activity Positive Regulation Of Cell Junction Assembly Regulation Of Intracellular Signal Transduction Regulation Of Cardiac Muscle Cell Action Potential
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