NDUFB10 and DUX4L9

Number of citations of the paper that reports this interaction (PubMedID 26816005)
133

Data Source:
BioGRID (two hybrid)

		NDUFB10	DUX4L9
Description		NADH:ubiquinone oxidoreductase subunit B10	double homeobox 4 like 9 (pseudogene)
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane Respiratory Chain Complex I
	Molecular Function	Protein Binding NADH Dehydrogenase (ubiquinone) Activity
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Aerobic Respiration Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport
Pathways		Respiratory electron transport Complex I biogenesis
Drugs		NADH
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
Interacting Genes		9 interacting genes: DUX4L9 FAM9B HGS HTR2A LIG4 POLR1C RNF181 UPF1 XRN1	10 interacting genes: ACTA1 ACTN3 FHL3 MSS51 MYH2 NDUFB10 RBM24 RPL4 SF1 VDAC2
Entrez ID		4716	100288711
HPRD ID		11958
Ensembl ID		ENSG00000140990	ENSG00000224807
Uniprot IDs		A8K761 O96000
PDB IDs		5XTC 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?		Histone MRNA Catabolic Process Histone MRNA Metabolic Process Positive Regulation Of Phosphatidylinositol Biosynthetic Process Regulation Of DNA Metabolic Process Nucleobase-containing Compound Catabolic Process G Protein-coupled Serotonin Receptor Complex 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine Binding Gq/11-coupled Serotonin Receptor Activity Sensitization Regulation Of DNA Biosynthetic Process Establishment Of Integrated Proviral Latency DNA Ligase (ATP) Activity DNA Ligase IV Complex Pro-B Cell Differentiation T Cell Receptor V(D)J Recombination Establishment Of Viral Latency Regulation Of Chromosome Organization DNA Ligase Activity DN2 Thymocyte Differentiation Double-stranded DNA Helicase Activity P-body Nuclear-transcribed MRNA Catabolic Process Supraspliceosomal Complex Regulation Of Telomere Maintenance MRNA Catabolic Process Positive Regulation Of MRNA Cis Splicing, Via Spliceosome ESCRT-0 Complex Phagocytic Vesicle Lumen Cellular Response To Puromycin 5'-3' RNA Exonuclease Activity Cellular Response To Cycloheximide	Sarcomere Actin Filament Muscle System Process Stress Fiber Regulation Of Myotube Differentiation Actin Binding Regulation Of Striated Muscle Cell Differentiation Positive Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Regulation Of The Force Of Skeletal Muscle Contraction Positive Regulation Of Striated Muscle Cell Differentiation Positive Regulation Of Fast-twitch Skeletal Muscle Fiber Contraction Positive Regulation Of Muscle Cell Differentiation Muscle Cell Development Actin Filament-based Process Positive Regulation Of Bone Mineralization Involved In Bone Maturation Focal Adhesion Positive Regulation Of Skeletal Muscle Fiber Differentiation Skeletal Muscle Thin Filament Assembly Mesenchyme Migration Negative Regulation Of Relaxation Of Muscle Regulation Of Muscle Cell Differentiation Response To Denervation Involved In Regulation Of Muscle Adaptation Positive Regulation Of Skeletal Muscle Tissue Growth Transition Between Fast And Slow Fiber Regulation Of Skeletal Muscle Tissue Growth Skeletal Muscle Atrophy Skeletal Muscle Adaptation Striated Muscle Atrophy Z Disc Porin Activity Voltage-gated Monoatomic Anion Channel Activity U2AF Complex MRNA 3'-splice Site Recognition Positive Regulation Of 3'-UTR-mediated MRNA Stabilization MRNA CDS Binding Regulation Of Skeletal Muscle Fiber Differentiation Striated Muscle Thin Filament Muscle Atrophy Response To Muscle Inactivity Positive Regulation Of Skeletal Muscle Fiber Development Negative Regulation Of Cellular Respiration Negative Regulation Of Oxidative Phosphorylation Ribosome Ceramide Binding Mitochondrial Outer Membrane Permeabilization Negative Regulation Of Cytoplasmic Translation Positive Regulation Of Skeletal Muscle Cell Differentiation Muscle Contraction Regulation Of Skeletal Muscle Fiber Development Actin Filament Binding
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