DNAJC2 and HSPA14

Number of citations of the paper that reports this interaction (PMID 16002468)
26

Data Source:
HPRD (in vitro)

		DNAJC2	HSPA14
Gene Name		DnaJ (Hsp40) homolog, subfamily C, member 2	heat shock 70kDa protein 14
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Nuclear Membrane	Cytosol Ribosome Membrane
	Molecular Function	DNA Binding Chromatin Binding Hsp70 Protein Binding Histone Binding Ubiquitin Binding Poly(A) RNA Binding	Protein Binding ATP Binding
	Biological Process	DNA Replication Transcription, DNA-templated Chromatin Modification Negative Regulation Of Cell Growth Positive Regulation Of Transcription, DNA-templated 'de Novo' Cotranslational Protein Folding Negative Regulation Of DNA Biosynthetic Process	'de Novo' Cotranslational Protein Folding
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: HIST2H2AA3 HSPA14	5 interactors: BARD1 BRCA1 DNAJC2 PAXIP1 STIP1
Entrez ID		27000	51182
HPRD ID		19072	07021
Ensembl ID		ENSG00000105821	ENSG00000187522
Uniprot IDs		Q99543	B0YIZ1 Q0VDF9 Q8TAQ0
PDB IDs		2M2E
Enriched GO Terms of Interacting Partners?		'de Novo' Cotranslational Protein Folding 'de Novo' Protein Folding	Protein K6-linked Ubiquitination Positive Regulation Of Histone H3-K4 Methylation Positive Regulation Of Histone Acetylation Regulation Of Histone H3-K4 Methylation Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Protein Acetylation DNA Metabolic Process Positive Regulation Of Histone Methylation Regulation Of Histone Acetylation Regulation Of Histone Methylation Positive Regulation Of Histone Modification DNA Damage Response, Signal Transduction By P53 Class Mediator DNA Repair Signal Transduction In Response To DNA Damage Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H3-K36 Methylation Positive Regulation Of Histone H4-K16 Acetylation Signal Transduction By P53 Class Mediator Regulation Of Histone Modification Positive Regulation Of Protein Ubiquitination Response To Ionizing Radiation Positive Regulation Of DNA Metabolic Process Negative Regulation Of MRNA 3'-end Processing 'de Novo' Cotranslational Protein Folding Positive Regulation Of Histone H3-K9 Acetylation Cellular Response To DNA Damage Stimulus Protein Polyubiquitination Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Regulation Of Chromosome Organization Regulation Of Protein Ubiquitination DNA Recombination Cellular Response To Indole-3-methanol Negative Regulation Of Centriole Replication Positive Regulation Of Protein Metabolic Process DNA Replication Negative Regulation Of Protein Export From Nucleus Dosage Compensation By Inactivation Of X Chromosome Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Histone H3-K9 Methylation Dosage Compensation Chorion Development Regulation Of Histone H3-K9 Acetylation Positive Regulation Of Metabolic Process Response To Stress Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Stress Regulation Of Centriole Replication Positive Regulation Of Gene Expression
Tagcloud ?		actually bear categorized cerevisiae contain dnaja1 dnajb1b domains dubbed folding highlights homologs hsp40 hsp70s hydrolysis introduces named names preserved saccharomyces stabilizing stresses studying unfolding	apg1 forelimb forelimbs grp94 hindlimb hindlimbs hsp10 hsp105 hsp110 hsp20 hsp22 hsp25 hsp47 hsp60 hspb10 hspb2 hspb3 hspb4 hspb7 hspb9 hsps oligodactylic performs phocomelic trap1
Tagcloud (Difference) ?		actually bear categorized cerevisiae contain dnaja1 dnajb1b domains dubbed folding highlights homologs hsp40 hsp70s hydrolysis introduces named names preserved saccharomyces stabilizing stresses studying unfolding	apg1 forelimb forelimbs grp94 hindlimb hindlimbs hsp10 hsp105 hsp110 hsp20 hsp22 hsp25 hsp47 hsp60 hspb10 hspb2 hspb3 hspb4 hspb7 hspb9 hsps oligodactylic performs phocomelic trap1
Tagcloud (Intersection) ?