TPD52 and ANXA6

Number of citations of the paper that reports this interaction (PMID 15576473)
6

Data Source:
HPRD (in vivo)

		TPD52	ANXA6
Gene Name		tumor protein D52	annexin A6
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Perinuclear Region Of Cytoplasm	Lysosomal Membrane Focal Adhesion Membrane Late Endosome Membrane Melanosome Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Calcium Ion Binding Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity	Calcium Ion Binding Protein Binding GTP Binding Calcium-dependent Phospholipid Binding Lipid Binding Ligand-gated Ion Channel Activity Cholesterol Binding Protein Homodimerization Activity Calcium-dependent Protein Binding
	Biological Process	Positive Regulation Of Cell Proliferation Anatomical Structure Morphogenesis B Cell Differentiation Secretion	Calcium Ion Transport Regulation Of Muscle Contraction Ion Transmembrane Transport Protein Homooligomerization
Pathways		Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS		Metabolite levels (HVA/MHPG ratio) ( 23319000)
Protein-Protein Interactions		8 interactors: ANXA6 MAL2 SENP2 SOCS2 SRPK2 TPD52L1 TPD52L2 TPD52L3	9 interactors: A2M CDC73 CR2 MLH1 RASA1 S100A1 S100B SNCA TPD52
Entrez ID		7163	309
HPRD ID		04963	00231
Ensembl ID		ENSG00000076554	ENSG00000197043
Uniprot IDs		P55327	A6NN80 P08133
PDB IDs			1M9I
Enriched GO Terms of Interacting Partners?			Developmental Process Cell Activation Leukocyte Activation B Cell Activation Cell Differentiation Protein Destabilization Long-term Synaptic Potentiation Regulation Of Neuronal Synaptic Plasticity Cellular Response To Stimulus Multicellular Organismal Development Anatomical Structure Development Negative Regulation Of Thrombin Receptor Signaling Pathway Positive Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of Glutathione Peroxidase Activity Meiotic Metaphase I Plate Congression Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Norepinephrine Uptake Meiotic Spindle Midzone Assembly MRNA 3'-end Processing Lymphocyte Activation Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Calcium Ion Transport Immune System Process B Cell Differentiation RNA 3'-end Processing Positive Regulation Of Voltage-gated Calcium Channel Activity Negative Regulation Of Mitotic Recombination Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Negative Regulation Of Complement Activation, Lectin Pathway Positive Regulation Of Synaptic Transmission Immune Response Regulation Of Immune System Process Signaling Cell Communication Negative Regulation Of Dopamine Metabolic Process Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Serotonin Uptake Negative Regulation Of Cellular Respiration Regulation Of Protein Stability Response To Stimulus Regulation Of Mitotic Recombination Male Meiosis Chromosome Segregation Negative Regulation Of Synaptic Transmission, Dopaminergic Negative Regulation Of Oxidative Phosphorylation Negative Regulation Of Skeletal Muscle Cell Differentiation System Development Regulation Of Cell Shape Regulation Of Synaptic Plasticity Protein Activation Cascade Regulation Of Signal Transduction
Tagcloud ?		adjuvant antigens autoimmunity broad burden class considers demonstrating efforts exhibiting expected focusing highlighting largest obstacle oncogenesis overcome overexpressed perhaps possibly preclinical preclude presumed promising shed subset tolerance understudied vaccine	1q21 5q31 6p21 alleles applicable atopic conduct dermatitis direction exclusive histocompatibility immunochip influencing loci methodologies mutually opposing overlap overlapping pleiotropic prkra psoriasis rarely shared th2 tnip1 traits unreported utilizing
Tagcloud (Difference) ?		adjuvant antigens autoimmunity broad burden class considers demonstrating efforts exhibiting expected focusing highlighting largest obstacle oncogenesis overcome overexpressed perhaps possibly preclinical preclude presumed promising shed subset tolerance understudied vaccine	1q21 5q31 6p21 alleles applicable atopic conduct dermatitis direction exclusive histocompatibility immunochip influencing loci methodologies mutually opposing overlap overlapping pleiotropic prkra psoriasis rarely shared th2 tnip1 traits unreported utilizing
Tagcloud (Intersection) ?