SH3GLB1 and DNM1

Number of citations of the paper that reports this interaction (PMID 12456676)
9

Data Source:
BioGRID (pull down)

		SH3GLB1	DNM1
Gene Name		SH3-domain GRB2-like endophilin B1	dynamin 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Cytoplasm Mitochondrial Outer Membrane Extracellular Vesicular Exosome	Microtubule Plasma Membrane Membrane Coat Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Lipid Binding Identical Protein Binding Protein Homodimerization Activity	GTPase Activity Protein Binding GTP Binding Protein C-terminus Binding Protein Kinase Binding Protein Complex Binding Identical Protein Binding Poly(A) RNA Binding Nitric-oxide Synthase Binding
	Biological Process	Apoptotic Process Positive Regulation Of Protein Oligomerization Protein Oligomerization	Endocytosis Receptor-mediated Endocytosis Endosome Organization Axon Guidance Receptor Internalization Ephrin Receptor Signaling Pathway Clathrin-mediated Endocytosis
Pathways			Retrograde neurotrophin signalling Signalling by NGF Formation of annular gap junctions Axon guidance Gap junction degradation Gap junction trafficking L1CAM interactions NGF signalling via TRKA from the plasma membrane Recycling pathway of L1 Toll-Like Receptors Cascades EPH-ephrin mediated repulsion of cells Toll Like Receptor 4 (TLR4) Cascade Gap junction trafficking and regulation MHC class II antigen presentation EPH-Ephrin signaling Adaptive Immune System Innate Immune System
Drugs
Diseases
GWAS			Attention deficit hyperactivity disorder ( 18839057)
Protein-Protein Interactions		22 interactors: ADAM15 ADAM9 AMPH APP ARHGAP17 BAX BIN1 CMTM5 DNM1 DNM2 FUNDC1 GADD45A GADD45G HTT MTA1 PSMA1 SH3GLB2 SH3KBP1 SYNJ1 TFIP11 TPD52L2 ZNF576	47 interactors: AMPH AP2A2 ASB13 BIN1 CABIN1 CAV1 CDK5 CLIC3 CLIC4 CLINT1 CTTN DNM2 DNMBP EPS15 FNBP1 GNB2L1 GRB2 GRIN1 GRIN2D ITSN1 KIAA1377 MAP3K10 MED31 MOB4 NCK1 NCK2 NME2 PACSIN1 PACSIN2 PACSIN3 PFN2 PIAS1 PIK3R1 PIN4 PLCG1 PRKCA PRNP SH3GL1 SH3GL2 SH3GL3 SH3GLB1 SNAP25 SNX9 SRC SUMO1 TIMM50 UBE2I
Entrez ID		51100	1759
HPRD ID		15333	03851
Ensembl ID		ENSG00000097033	ENSG00000106976
Uniprot IDs		Q9Y371	Q05193
PDB IDs			1DYN 2DYN 2X2E 2X2F 3SNH 3ZYC 3ZYS
Enriched GO Terms of Interacting Partners?		Endocytosis Learning Regulation Of Cell Cycle Regulation Of Catalytic Activity Apoptotic Process Programmed Cell Death Vesicle-mediated Transport Neuron Apoptotic Process Cell Death Death Activation Of MAPKKK Activity Positive Regulation Of P38MAPK Cascade Neuron Death Positive Regulation Of Catalytic Activity Establishment Of Vesicle Localization Positive Regulation Of Cellular Protein Metabolic Process Vesicle Localization Signaling Response To Radiation Single-organism Behavior Cell Communication Positive Regulation Of Metabolic Process Positive Regulation Of Protein Metabolic Process Learning Or Memory Regulation Of P38MAPK Cascade Cognition Regulation Of Signaling Regulation Of Cellular Process Positive Regulation Of Proteolysis Synaptic Vesicle Transport Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Behavior Positive Regulation Of Cell Death Regulation Of Apoptotic Process Establishment Of Organelle Localization Response To Light Stimulus Regulation Of Cell Death Response To Abiotic Stimulus Response To Ionizing Radiation Response To Stress Regulation Of Protein Binding Regulation Of Signal Transduction Positive Regulation Of Transport Regulation Of Mitochondrial Membrane Potential Regulation Of Mitochondrial Membrane Permeability Organelle Localization Endoplasmic Reticulum Calcium Ion Homeostasis Synaptic Vesicle Endocytosis Signal Transduction	Endocytosis Vesicle-mediated Transport Regulation Of Cellular Component Organization Positive Regulation Of Protein Complex Assembly Cell Projection Morphogenesis Cell Part Morphogenesis Cell Morphogenesis Cellular Component Assembly Neuron Projection Morphogenesis Positive Regulation Of Cellular Component Biogenesis Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Membrane Organization Transport Axon Guidance Cell Projection Organization Regulation Of Signaling Neuron Projection Development Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Protein Complex Assembly Vascular Endothelial Growth Factor Receptor Signaling Pathway Chemotaxis Synaptic Vesicle Transport Regulation Of Vesicle-mediated Transport Regulation Of Endocytosis Neuron Development Generation Of Neurons Membrane Tubulation Signaling Axonogenesis Anatomical Structure Development Protein Complex Assembly Neurogenesis Cell Communication Anatomical Structure Morphogenesis Locomotion Neurotrophin TRK Receptor Signaling Pathway Synaptic Vesicle Endocytosis Cell Morphogenesis Involved In Differentiation Axon Development Enzyme Linked Receptor Protein Signaling Pathway Synaptic Vesicle Recycling Regulation Of Signal Transduction Neurotrophin Signaling Pathway Regulation Of Phosphorylation Cell Morphogenesis Involved In Neuron Differentiation Synaptic Transmission Positive Regulation Of Metabolic Process Neuron Differentiation Negative Regulation Of Endocytosis
Tagcloud ?			a432t a452v ankk1 arrb2 cdh13 chrna2 chrna9 dbh drd2 eas fagerstrom gabbr2 grin3a mstcc n549s nrxn1 nrxn2 nrxn3 ntrk2 r480h rs139982841 rs142807401 rs34755188 rs75981117 skat tas2r38 v132l v389l wss
Tagcloud (Difference) ?			a432t a452v ankk1 arrb2 cdh13 chrna2 chrna9 dbh drd2 eas fagerstrom gabbr2 grin3a mstcc n549s nrxn1 nrxn2 nrxn3 ntrk2 r480h rs139982841 rs142807401 rs34755188 rs75981117 skat tas2r38 v132l v389l wss
Tagcloud (Intersection) ?