CACFD1 and MTERF3

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		CACFD1	MTERF3
Name		calcium channel flower domain containing 1	mitochondrial transcription termination factor 3
Structure		No pdb structure
GO Annotations	Cellular Component	Endosome Early Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Vesicle Synapse Recycling Endosome	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Matrix Cytosol
	Molecular Function	Protein Binding	Transcription Cis-regulatory Region Binding Nucleic Acid Binding DNA Binding Protein Binding
	Biological Process	Vesicle-mediated Transport	Regulation Of DNA-templated Transcription Ribosome Biogenesis Negative Regulation Of DNA-templated Transcription Mitochondrial Ribosome Assembly Regulation Of Mitochondrial Transcription
Pathways		None	PINK1-PRKN Mediated Mitophagy rRNA modification in the mitochondrion Mitochondrial mRNA modification
GWAS		Gut microbiota (functional units) ( 27694959 )	No GWAS studies recorded
Novel Interactors		1 novel interactors: EXOSC2	None recorded
Interacting Genes		11 interacting genes: CREB3 HSFX1 HSFX2 LDAF1 MTERF3 NDRG4 PITPNC1 PNKP RBFA SH3GLB1 SNCA	28 interacting genes: ADGRE2 AGTRAP APOC1 APP ARL6IP1 CACFD1 CMTM5 ERG28 FADS6 FUNDC1 GPR108 HIGD1C MAL2 MIR34B PBX3 RHBDD2 SCAMP1 SLC17A9 SLC2A5 SLC50A1 STX8 SYNGR1 SYP TMEM14C UPF2 YIF1A ZDHHC21 ZFPL1
Entrez ID		11094	51001
HPRD ID		12974	10823
Ensembl ID		ENSG00000160325	ENSG00000156469
Uniprot IDs		Q9UGQ2	E5RIK9 Q96E29
PDB IDs		Not available	3M66
GO Terms Enriched among Interactors		Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Mitochondrial Outer Membrane Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Fatty Acid Binding Positive Regulation Of Deacetylase Activity Protein Localization To Vacuolar Membrane	Membrane Regulation Of Long-term Neuronal Synaptic Plasticity Golgi Apparatus Regulation Of Neuronal Synaptic Plasticity Regulation Of Short-term Neuronal Synaptic Plasticity Synaptic Vesicle Membrane Organization Endoplasmic Reticulum Very-low-density Lipoprotein Particle Vesicle-mediated Transport Golgi Membrane