Gene Name |
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 |
matrix metallopeptidase 3 (stromelysin 1, progelatinase) |
Image |
No pdb structure |
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Gene Ontology Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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- Marimastat
- N-Hydroxy 1n(4-Methoxyphenyl)Sulfonyl-4-(Z,E-N-Methoxyimino)Pyrrolidine-2r-Carboxamide
- 3-Methylpyridine
- A Disubstituted Succinyl Caprolactam Hydroxymate Mmp3inhibitor
- N-Hydroxy-4-[(4-Methoxylphenyl)Sulfonyl]-2,2-Dimethyl-Hexahydro-1,4-Thiazepine-3(S)-Carboxamide
- (1n)-4-N-Butoxyphenylsulfonyl-(2r)-N-Hydroxycarboxamido-(4s)-Methanesulfonylamino-Pyrrolidine
- 3-(1h-Indol-3-Yl)-2-[4-(4-Phenyl-Piperidin-1-Yl)-Benzenesulfonylamino]-Propionic Acid
- Hydroxyaminovaline
- 1-Methyloxy-4-Sulfone-Benzene
- 5-Methyl-5-(4-Phenoxy-Phenyl)-Pyrimidine-2,4,6-Trione
- 1-Benzyl-3-(4-Methoxy-Benzenesulfonyl)-6-Oxo-Hexahydro-Pyrimidine-4-Carboxylic Acid Hydroxyamide
- N-Hydroxy-1-(4-Methoxyphenyl)Sulfonyl-4-Benzyloxycarbonyl-Piperazine-2-Carboxamide
- R-2-{[4\'-Methoxy-(1,1\'-Biphenyl)-4-Yl]-Sulfonyl}-Amino-6-Methoxy-Hex-4-Ynoic Acid
- 2-[3-(5-MERCAPTO-[1,3,4]THIADIAZOL-2-YL)-UREIDO]-N-METHYL-3-PHENYL-PROPIONAMIDE
- [4-(4-PHENYL-PIPERIDIN-1-YL)-BENZENESULFONYLAMINO]-ACETIC ACID
- [2-(5-MERCAPTO-[1,3,4]THIADIAZOL-2-YLCARBAMOYL)-1-PHENYL-ETHYL]-CARBAMIC ACID BENZYL ESTER
- 2-[3-(5-MERCAPTO-[1,3,4]THIADIAZOL-2YL)-UREIDO]-N-METHYL-3-PENTAFLUOROPHENYL-PROPIONAMIDE
- N~2~-(biphenyl-4-ylsulfonyl)-N-hydroxy-N~2~-(2-hydroxyethyl)glycinamide
- 3-[(4\'-cyanobiphenyl-4-yl)oxy]-N-hydroxypropanamide
- N-ISOBUTYL-N-[4-METHOXYPHENYLSULFONYL]GLYCYL HYDROXAMIC ACID
- N-[[2-METHYL-4-HYDROXYCARBAMOYL]BUT-4-YL-N]-BENZYL-P-[PHENYL]-P-[METHYL]PHOSPHINAMID
- 2-(2-{2-[(BIPHENYL-4-YLMETHYL)-AMINO]-3-MERCAPTO-PENTANOYLAMINO}-ACETYLAMINO)-3-METHYL-BUTYRIC ACID METHYL ESTER
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Diseases |
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GWAS |
- Immune reponse to smallpox (secreted IL-10) ( 22610502)
- Obesity-related traits ( 23251661)
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Protein-Protein Interactions |
3 interactors:
MMP14
MMP3
SPOCK2
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18 interactors:
ACAN
BCAN
CCL13
CCL2
CCL7
CCL8
DCN
HAPLN1
IGFBP3
MEOX2
PLG
SERPINE1
SPOCK1
SPOCK3
SPP1
TIMP1
TIMP3
TNFSF11
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Entrez ID |
50859 |
4314 |
HPRD ID |
12147 |
01703 |
Ensembl ID |
ENSG00000196104
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ENSG00000149968
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Uniprot IDs |
B4DI52
B4DJY3
Q9BQ16
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P08254
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PDB IDs |
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1B3D
1B8Y
1BIW
1BM6
1BQO
1C3I
1C8T
1CAQ
1CIZ
1CQR
1D5J
1D7X
1D8F
1D8M
1G05
1G49
1G4K
1HFS
1HY7
1M1W
1OO9
1QIA
1QIC
1SLM
1SLN
1UEA
1UMS
1UMT
1USN
2D1O
2JNP
2JT5
2JT6
2SRT
2USN
3OHL
3OHO
3USN
4DPE
4G9L
4JA1
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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6j
adp
articular
blotting
c57bl
chondrocyte
chondrocytes
degeneration
eicosapentaenoic
epa
inc
intra
metalloproteinases
mmp13
mmps
nitroprusside
oa
orthop
orthopaedic
osteoarthritis
periodicals
poly
polyunsaturated
reduces
res
ribose
snp
society
wiley
|
Tagcloud (Difference) ? |
|
6j
adp
articular
blotting
c57bl
chondrocyte
chondrocytes
degeneration
eicosapentaenoic
epa
inc
intra
metalloproteinases
mmp13
mmps
nitroprusside
oa
orthop
orthopaedic
osteoarthritis
periodicals
poly
polyunsaturated
reduces
res
ribose
snp
society
wiley
|
Tagcloud (Intersection) ? |
|