IL22 and IL22RA2

Number of citations of the paper that reports this interaction (PMID 11390453)
21

Data Source:
HPRD (in vitro)

		IL22	IL22RA2
Gene Name		interleukin 22	interleukin 22 receptor, alpha 2
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Space Cytosol Plasma Membrane Integral Component Of Membrane
	Molecular Function	Cytokine Activity Interleukin-22 Receptor Binding	Interleukin-22 Binding Interleukin-22 Receptor Activity
	Biological Process	Acute-phase Response Inflammatory Response Cell-cell Signaling Response To Glucocorticoid	Cytokine-mediated Signaling Pathway Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Negative Regulation Of Inflammatory Response
Pathways
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233) Ulcerative colitis ( 19122664)	Multiple sclerosis ( 21833088)
Protein-Protein Interactions		3 interactors: IL10RB IL22RA1 IL22RA2	1 interactors: IL22
Entrez ID		50616	116379
HPRD ID		05621	05973
Ensembl ID		ENSG00000127318	ENSG00000164485
Uniprot IDs		Q9GZX6	Q969J5
PDB IDs		1M4R 1YKB 3DGC 3DLQ 3G9V 3Q1S	3G9V
Enriched GO Terms of Interacting Partners?		Cytokine-mediated Signaling Pathway Cellular Response To Cytokine Stimulus Response To Cytokine Cellular Response To Organic Substance Response To Organic Substance Cell Surface Receptor Signaling Pathway Response To Other Organism Response To Biotic Stimulus Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Defense Response To Gram-negative Bacterium Defense Response Signal Transduction Regulation Of JAK-STAT Cascade Negative Regulation Of Inflammatory Response Signaling Cell Communication Response To External Stimulus Defense Response To Virus Cellular Response To Stimulus	Acute-phase Response Acute Inflammatory Response Response To Glucocorticoid Response To Corticosteroid
Tagcloud ?		aucs bead constituted crp discriminated discriminative erythrocyte follows ifngamma il10 il12p70 il13 il17 il1beta il4 il5 il6 il9 immunoassay inverse multiplex object pct procalcitonin sedimentation sepsis septic sirs
Tagcloud (Difference) ?		aucs bead constituted crp discriminated discriminative erythrocyte follows ifngamma il10 il12p70 il13 il17 il1beta il4 il5 il6 il9 immunoassay inverse multiplex object pct procalcitonin sedimentation sepsis septic sirs
Tagcloud (Intersection) ?