IL22 and IL22RA1

Number of citations of the paper that reports this interaction (PMID 11035029)
60

Data Source:
HPRD (in vivo)

		IL22	IL22RA1
Gene Name		interleukin 22	interleukin 22 receptor, alpha 1
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Cytokine Activity Interleukin-22 Receptor Binding	Cytokine Receptor Activity Interferon Receptor Activity Interleukin-20 Binding
	Biological Process	Acute-phase Response Inflammatory Response Cell-cell Signaling Response To Glucocorticoid	Biological_process Cytokine-mediated Signaling Pathway Defense Response To Gram-negative Bacterium
Pathways
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233) Ulcerative colitis ( 19122664)
Protein-Protein Interactions		3 interactors: IL10RB IL22RA1 IL22RA2	2 interactors: IL22 STAT3
Entrez ID		50616	58985
HPRD ID		05621	16108
Ensembl ID		ENSG00000127318	ENSG00000142677
Uniprot IDs		Q9GZX6	Q8N6P7
PDB IDs		1M4R 1YKB 3DGC 3DLQ 3G9V 3Q1S	3DGC 3DLQ
Enriched GO Terms of Interacting Partners?		Cytokine-mediated Signaling Pathway Cellular Response To Cytokine Stimulus Response To Cytokine Cellular Response To Organic Substance Response To Organic Substance Cell Surface Receptor Signaling Pathway Response To Other Organism Response To Biotic Stimulus Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Defense Response To Gram-negative Bacterium Defense Response Signal Transduction Regulation Of JAK-STAT Cascade Negative Regulation Of Inflammatory Response Signaling Cell Communication Response To External Stimulus Defense Response To Virus Cellular Response To Stimulus	Acute-phase Response Acute Inflammatory Response Inflammatory Response Response To Steroid Hormone Negative Regulation Of Glycolytic Process Radial Glial Cell Differentiation Interleukin-6-mediated Signaling Pathway Response To Lipid Response To Organic Cyclic Compound Response To Hormone JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Temperature Homeostasis Growth Hormone Receptor Signaling Pathway Regulation Of Glycolytic Process Cellular Response To Growth Hormone Stimulus Cellular Response To Interleukin-6 Positive Regulation Of Notch Signaling Pathway Eating Behavior Negative Regulation Of Neuron Migration Response To Interleukin-6 Defense Response Response To Growth Hormone Astrocyte Differentiation Eye Photoreceptor Cell Differentiation JAK-STAT Cascade Regulation Of Neuron Migration Regulation Of Notch Signaling Pathway Somatic Stem Cell Maintenance Regulation Of Generation Of Precursor Metabolites And Energy
Tagcloud ?		aucs bead constituted crp discriminated discriminative erythrocyte follows ifngamma il10 il12p70 il13 il17 il1beta il4 il5 il6 il9 immunoassay inverse multiplex object pct procalcitonin sedimentation sepsis septic sirs
Tagcloud (Difference) ?		aucs bead constituted crp discriminated discriminative erythrocyte follows ifngamma il10 il12p70 il13 il17 il1beta il4 il5 il6 il9 immunoassay inverse multiplex object pct procalcitonin sedimentation sepsis septic sirs
Tagcloud (Intersection) ?