IL22RA2 and IL22

Number of citations of the paper that reports this interaction (PubMedID 11390453)
0

Data Source:
HPRD (in vitro)

		IL22RA2	IL22
Description		interleukin 22 receptor subunit alpha 2	interleukin 22
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytosol Plasma Membrane	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Receptor Activity Interleukin-22 Binding Interleukin-22 Receptor Activity	Cytokine Activity Protein Binding Interleukin-22 Receptor Binding
	Biological Process	Cytokine-mediated Signaling Pathway Negative Regulation Of Inflammatory Response Interleukin-22-mediated Signaling Pathway	Acute-phase Response Inflammatory Response Signal Transduction Negative Regulation Of Inflammatory Response Response To Glucocorticoid
Pathways		Interleukin-20 family signaling	Interleukin-20 family signaling Signaling by ALK fusions and activated point mutants
Drugs
Diseases
GWAS		Multiple sclerosis ( 21833088 24076602)	Alopecia areata ( 25608926) Inflammatory bowel disease ( 23128233) Ulcerative colitis ( 19122664)
Interacting Genes		1 interacting genes: IL22	5 interacting genes: IL10RB IL22RA1 IL22RA2 S100A6 S100P
Entrez ID		116379	50616
HPRD ID		05973	05621
Ensembl ID		ENSG00000164485	ENSG00000127318
Uniprot IDs		Q969J5	A0A7R8C389 Q9GZX6
PDB IDs		3G9V	1M4R 1YKB 3DGC 3DLQ 3G9V 3Q1S
Enriched GO Terms of Interacting Partners?		Nuclear Matrix Organization Cytoskeleton-nuclear Membrane Anchor Activity Nuclear Matrix Anchoring At Nuclear Membrane Interleukin-22 Receptor Binding Meiotic Nuclear Membrane Microtubule Tethering Complex Lamin Binding Maintenance Of Protein Location In Nucleus Nuclear Outer Membrane Maintenance Of Protein Localization In Organelle Acute-phase Response Maintenance Of Protein Location In Cell Sarcomere Maintenance Of Protein Location Acute Inflammatory Response Maintenance Of Location In Cell Maintenance Of Location	Interleukin-22 Receptor Activity Interleukin-22-mediated Signaling Pathway Cytokine Receptor Activity Cytokine-mediated Signaling Pathway Calcium-dependent Protein Binding Interleukin-22 Binding Interleukin-10 Receptor Activity Interferon Receptor Activity Interleukin-28 Receptor Complex Interleukin-20 Binding Negative Regulation Of Inflammatory Response Plasma Membrane Type III Interferon-mediated Signaling Pathway Interleukin-10-mediated Signaling Pathway Negative Regulation Of Defense Response Positive Regulation Of Cellular Respiration Monoatomic Ion Transmembrane Transporter Activity Tropomyosin Binding S100 Protein Binding Transition Metal Ion Binding Regulation Of Inflammatory Response Microvillus Membrane
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