IL22

Description		interleukin 22
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Activity Protein Binding Interleukin-22 Receptor Binding
	Biological Process	Acute-phase Response Inflammatory Response Signal Transduction Negative Regulation Of Inflammatory Response Response To Glucocorticoid
Pathways		Interleukin-20 family signaling Signaling by ALK fusions and activated point mutants
Drugs
Diseases
GWAS		Alopecia areata ( 25608926) Inflammatory bowel disease ( 23128233) Ulcerative colitis ( 19122664)
Interacting Genes		5 interacting genes: IL10RB IL22RA1 IL22RA2 S100A6 S100P
Entrez ID		50616
HPRD ID		05621
Ensembl ID		ENSG00000127318
Uniprot IDs		A0A7R8C389 Q9GZX6
PDB IDs		1M4R 1YKB 3DGC 3DLQ 3G9V 3Q1S
Enriched GO Terms of Interacting Partners?		Interleukin-22 Receptor Activity Interleukin-22-mediated Signaling Pathway Cytokine Receptor Activity Cytokine-mediated Signaling Pathway Calcium-dependent Protein Binding Interleukin-22 Binding Interleukin-10 Receptor Activity Interferon Receptor Activity Interleukin-28 Receptor Complex Interleukin-20 Binding Negative Regulation Of Inflammatory Response Plasma Membrane Type III Interferon-mediated Signaling Pathway Interleukin-10-mediated Signaling Pathway Negative Regulation Of Defense Response Positive Regulation Of Cellular Respiration Monoatomic Ion Transmembrane Transporter Activity Tropomyosin Binding S100 Protein Binding Transition Metal Ion Binding Regulation Of Inflammatory Response Microvillus Membrane
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