ODF1 and CDK5R1

Number of citations of the paper that reports this interaction (PMID 17762160)
2

Data Source:
BioGRID (enzymatic study)

		ODF1	CDK5R1
Gene Name		outer dense fiber of sperm tails 1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Outer Dense Fiber Nucleus	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Postsynaptic Density Membrane Cyclin-dependent Protein Kinase 5 Holoenzyme Complex Axon Dendrite Growth Cone Neuromuscular Junction Neuronal Cell Body Dendritic Spine Intracellular Membrane-bounded Organelle Contractile Fiber Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Domain Specific Binding	Protein Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity Calcium Ion Binding Protein Binding Kinase Activity Cyclin-dependent Protein Kinase 5 Activator Activity Protein Kinase Binding Protein Serine/threonine Kinase Activator Activity Cadherin Binding Ephrin Receptor Binding
	Biological Process	Multicellular Organismal Development Spermatogenesis Cell Differentiation	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Neuron Migration Neuron Cell-cell Adhesion G-protein Coupled Acetylcholine Receptor Signaling Pathway Axon Guidance Axonal Fasciculation Brain Development Cell Proliferation Embryo Development Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Cerebellum Development Superior Olivary Nucleus Maturation Hippocampus Development Layer Formation In Cerebral Cortex Neuron Differentiation Negative Regulation Of Axon Extension Neuron Projection Development Regulation Of Actin Cytoskeleton Organization Serine Phosphorylation Of STAT3 Protein Ionotropic Glutamate Receptor Signaling Pathway Positive Regulation Of Neuron Apoptotic Process Regulation Of Neuron Differentiation Negative Regulation Of Transcription, DNA-templated Ephrin Receptor Signaling Pathway Rhythmic Process Regulation Of Dendritic Spine Morphogenesis Regulation Of Microtubule Cytoskeleton Organization Positive Regulation Of Cell Cycle Arrest Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Protein Targeting To Membrane
Pathways			Axon guidance Semaphorin interactions CRMPs in Sema3A signaling
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: CDK5R1 KLC1 KRTAP12-2 MTUS2 ODF2 SPAG4 SPAG5 TRIP6	31 interactors: ACTN1 AMPH APP BLOC1S6 CAMK2A CAPN1 CAPN2 CDK16 CDK5 CDK5RAP1 CDK5RAP2 CDK5RAP3 CDK9 CHN1 CTNNB1 HSP90AA1 KRT40 KRTAP10-3 LMTK2 MAPT MTUS2 NEDD4 NES NOTCH2NL ODF1 PAK1 SET SIAH1 STXBP1 TSC22D4 TTBK1
Entrez ID		4956	8851
HPRD ID		01687	04586
Ensembl ID		ENSG00000155087	ENSG00000176749
Uniprot IDs		Q14990	Q15078 Q8N619
PDB IDs			1H4L 1UNG 1UNH 1UNL 3O0G
Enriched GO Terms of Interacting Partners?		Superior Olivary Nucleus Maturation Stress Granule Disassembly Regulation Of Microtubule Cytoskeleton Organization Regulation Of Protein Localization Positive Regulation Of Intracellular Protein Transport Regulation Of Microtubule-based Process Pons Maturation Regulation Of Organelle Organization Serine Phosphorylation Of STAT3 Protein Release Of Cytoplasmic Sequestered NF-kappaB Serine Phosphorylation Of STAT Protein Regulation Of Cellular Localization Positive Regulation Of Intracellular Transport Regulation Of Intracellular Protein Transport Positive Regulation Of Protein Transport Pons Development G-protein Coupled Acetylcholine Receptor Signaling Pathway Organelle Organization Neuron Cell-cell Adhesion Regulation Of Attachment Of Spindle Microtubules To Kinetochore	Generation Of Neurons Nervous System Development Neurogenesis Establishment Of Localization In Cell Neuron Projection Development Cellular Localization Neuron Differentiation Cell Differentiation Cell Projection Organization Neuron Development Multicellular Organismal Development Vesicle-mediated Transport Regulation Of Organelle Organization Regulation Of Neurogenesis Establishment Of Organelle Localization Regulation Of Cellular Component Organization Developmental Process Cell Morphogenesis Involved In Differentiation Exocytosis Axonogenesis Synaptic Vesicle Transport Regulation Of Neuron Differentiation Cell Morphogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Cell Projection Morphogenesis Cell Development Regulation Of Cell Development System Development Cell Part Morphogenesis Organelle Localization Neuron Projection Morphogenesis Receptor Catabolic Process Anatomical Structure Development Synapse Organization Regulation Of Cytoskeleton Organization Secretion By Cell Brain Development Receptor Metabolic Process Response To Abiotic Stimulus Head Development Establishment Of Vesicle Localization Negative Regulation Of Neuron Death Vesicle Localization Axon Guidance Regulation Of Cell Differentiation Secretion Anatomical Structure Morphogenesis Regulation Of Cell Cycle Locomotion
Tagcloud ?		acev2 acu akap3 akap4v2 configurations degenerate frames gapdhs hundreds hypothetical noncanonical orthologous paralogues permutations prm1 prm2 prm3 resemble retrogene retroposons smcp spata18 spermatids tnp1 tnp2 uac utrs yrs yrss	10a 200c 30a 30c arhgap5 cd36 cdh2 chips cyp27b1 figure gemcitabine gna13 gp5 hist1h2bf hlf igsf3 ikbkb il32 intriguing mirs nrp2 oxidoreductase pak7 putatively rab23 rap2a slc11a1 sod3 tp53i3
Tagcloud (Difference) ?		acev2 acu akap3 akap4v2 configurations degenerate frames gapdhs hundreds hypothetical noncanonical orthologous paralogues permutations prm1 prm2 prm3 resemble retrogene retroposons smcp spata18 spermatids tnp1 tnp2 uac utrs yrs yrss	10a 200c 30a 30c arhgap5 cd36 cdh2 chips cyp27b1 figure gemcitabine gna13 gp5 hist1h2bf hlf igsf3 ikbkb il32 intriguing mirs nrp2 oxidoreductase pak7 putatively rab23 rap2a slc11a1 sod3 tp53i3
Tagcloud (Intersection) ?