CISD2 and RUSF1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CISD2	RUSF1
Description		CDGSH iron sulfur domain 2	RUS family member 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Protein-containing Complex Perinuclear Endoplasmic Reticulum	Membrane
	Molecular Function	RNA Binding Protein Binding Protein Homodimerization Activity Metal Ion Binding Iron-sulfur Cluster Binding 2 Iron, 2 Sulfur Cluster Binding	Protein Binding
	Biological Process	Autophagy Of Mitochondrion Autophagy Regulation Of Autophagy
Pathways
Drugs
Diseases		Wolfram syndrome (WFS); DIDMOAD syndrome
GWAS		Asthma and attention deficit hyperactivity disorder ( 31619474) Estimated glomerular filtration rate ( 31152163) Primary biliary cholangitis ( 26394269) Schizophrenia ( 28991256) Type 2 diabetes ( 28869590)
Interacting Genes		58 interacting genes: AIG1 APOL2 APP AQP10 ARLN BCL2L2 BET1 BMP10 BTN2A2 C14orf180 C2CD2L CDIPT CFHR5 CLDN10 CLN6 CYBC1 EHHADH EMD FAM241B GALNT15 GAST GPR37L1 HHATL IER3 KIR2DL3 LEPROTL1 LRP10 MAN2B2 MIP NAPB NRG4 NSG1 PGAP2 PLPP4 PLPPR2 PNKP POMGNT1 RTP2 RUSF1 SEC22A SERP2 SLC13A3 SLC35B4 SMIM1 SNORC SPP1 STX12 STX7 THSD7B TMEM187 TMEM243 TMEM43 TMEM86A TSPAN33 TTPA VAMP4 VKORC1L1 YIPF6	53 interacting genes: AQP6 ARL13B ARL6IP6 BIK C5orf46 CISD2 CMTM5 CREB3 CREB3L1 CREB3L3 DGAT2L6 DHRSX EBP EHHADH ERGIC3 FAM209A FCER1G FFAR2 FKBP7 GJA8 GPR42 HSD17B13 IFNGR1 IL10RA ITGAM LHFPL5 LMNA MMGT1 MS4A4A ODF4 PDCD1LG2 PGRMC2 PSCA PVR RETREG3 RNF5 SCN3B SFXN3 SLC10A1 SLC10A6 SLC30A8 SLC35E3 SLC35H1 SPAG4 SSMEM1 TEX29 TMEM237 TMEM248 TMEM35A TMX2 UBE2I ZCCHC12 ZDHHC15
Entrez ID		493856	64755
HPRD ID		17413	07839
Ensembl ID		ENSG00000145354	ENSG00000140688
Uniprot IDs		Q8N5K1	Q96GQ5
PDB IDs		3FNV 4OO7 4OOA 7P0P
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Protein Binding Endoplasmic Reticulum SNAP Receptor Activity SNARE Complex Lipid Metabolic Process	Membrane Endoplasmic Reticulum Protein Binding Positive Regulation Of Acute Inflammatory Response Endoplasmic Reticulum Membrane Bile Acid:sodium Symporter Activity Acetylcholine Receptor Regulator Activity
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