CISD2

Gene Name		CDGSH iron sulfur domain 2
Image
Gene Ontology Annotations	Cellular Component	Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Protein Complex
	Molecular Function	Protein Binding Protein Homodimerization Activity Poly(A) RNA Binding Metal Ion Binding 2 Iron, 2 Sulfur Cluster Binding
	Biological Process	Mitochondrion Degradation Multicellular Organismal Aging Regulation Of Autophagy
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: APP SPP1
Entrez ID		493856
HPRD ID		17413
Ensembl ID
Uniprot IDs		Q8N5K1
PDB IDs		3FNV
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Neuron Differentiation Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Regulation Of Developmental Growth Negative Regulation Of Neurogenesis Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Synaptic Growth At Neuromuscular Junction Negative Regulation Of Cell Development Collateral Sprouting In Absence Of Injury Extracellular Matrix Organization Extracellular Structure Organization Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Collateral Sprouting Axon Choice Point Recognition Regulation Of Neuron Differentiation Negative Regulation Of Axon Regeneration Chemotaxis Regulation Of Growth Neuron Remodeling Regulation Of Neurogenesis Negative Regulation Of Cell Differentiation Positive Regulation Of Bone Resorption Regulation Of Cell Development Regulation Of Axon Regeneration Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Reproduction Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Tissue Remodeling Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Decidualization Response To Vitamin D Cell Adhesion Mating Behavior Locomotion Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Bone Resorption RNA Polyadenylation Neuron Recognition Reproductive Process Defense Response Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Maternal Placenta Development Ionotropic Glutamate Receptor Signaling Pathway Regulation Of Bone Remodeling Regulation Of G2/M Transition Of Mitotic Cell Cycle
Tagcloud ?		4q aging autophagic autophagy breakdown centenarian comparative created delay drives elucidated evolutionarily extension gives homeostasis interconnected knockout lifespan lived longevity mammals mapped organism pathophysiology premature shortened shortens siblings wolfram