CNOT3 and CAND1

Number of citations of the paper that reports this interaction (PMID 12207886)
1

Data Source:
HPRD (in vitro, two hybrid)

		CNOT3	CAND1
Gene Name		CCR4-NOT transcription complex, subunit 3	cullin-associated and neddylation-dissociated 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasmic MRNA Processing Body Nucleus Cytosol CCR4-NOT Complex	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Membrane Cullin-RING Ubiquitin Ligase Complex Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Protein Binding TBP-class Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nuclear-transcribed MRNA Poly(A) Tail Shortening Trophectodermal Cell Differentiation Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Translation Gene Expression Gene Silencing By RNA Regulation Of Stem Cell Maintenance	SCF Complex Assembly Protein Ubiquitination Cell Differentiation Negative Regulation Of Catalytic Activity Positive Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly
Pathways		Deadenylation of mRNA Deadenylation-dependent mRNA decay
Drugs
Diseases
GWAS			Hippocampal atrophy ( 19668339)
Protein-Protein Interactions		7 interactors: CAND1 CAND2 CNOT1 CNOT2 CNOT8 CREBBP ID3	10 interactors: CNOT3 CUL1 CUL2 CUL3 CUL4A CUL4B DCUN1D1 RBX1 SRPK2 UBE2M
Entrez ID		4849	55832
HPRD ID		05368	06983
Ensembl ID		ENSG00000088038
Uniprot IDs		O75175	Q86VP6
PDB IDs			1U6G 4A0C
Enriched GO Terms of Interacting Partners?		Nuclear-transcribed MRNA Poly(A) Tail Shortening RNA Phosphodiester Bond Hydrolysis, Exonucleolytic SCF Complex Assembly Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Positive Regulation Of Cytoplasmic MRNA Processing Body Assembly Gene Silencing By RNA MRNA 3'-end Processing Regulation Of Cytoplasmic MRNA Processing Body Assembly Gene Silencing RNA 3'-end Processing RNA Phosphodiester Bond Hydrolysis Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Transcription, DNA-templated Regulation Of Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Nuclear-transcribed MRNA Catabolic Process Regulation Of RNA Metabolic Process MRNA Catabolic Process Negative Regulation Of Gene Expression Regulation Of Stem Cell Maintenance Positive Regulation Of MRNA Catabolic Process RNA Catabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Intracellular Estrogen Receptor Signaling Pathway Positive Regulation Of Organelle Assembly Negative Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Gene Silencing By MiRNA Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Translation Posttranscriptional Gene Silencing Gene Expression Positive Regulation Of Cellular Component Biogenesis Cellular Macromolecule Biosynthetic Process Nucleic Acid Phosphodiester Bond Hydrolysis Macromolecule Biosynthetic Process Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process MRNA Processing Aromatic Compound Catabolic Process Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Biosynthetic Process	Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Monoubiquitination Cellular Macromolecule Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Cell Cycle Arrest G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle Intrinsic Apoptotic Signaling Pathway Catabolic Process Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Cellular Protein Modification Process Protein Neddylation Apoptotic Signaling Pathway Proteolysis Positive Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Cellular Protein Metabolic Process Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Cell Cycle G1/S Phase Transition Trophectodermal Cell Differentiation Viral Process Positive Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Regulation Of Cell Cycle Phase Transition Cell Cycle Mitotic Cell Cycle Process Blastocyst Formation Mitotic Cell Cycle Regulation Of Cell Proliferation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Protein Metabolic Process Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Neuron Apoptotic Process Nuclear Speck Organization Regulation Of Nucleotide-excision Repair Positive Regulation Of Neuron Death
Tagcloud ?			cdk2 character diagnomx diagnosticpathology differentially dysregulated enrichment eu failure hope http hub omnibus ontology pls powerful preventive rela representation shed signatures slide slides smurf1 squares srsf1 virtual www ywhae
Tagcloud (Difference) ?			cdk2 character diagnomx diagnosticpathology differentially dysregulated enrichment eu failure hope http hub omnibus ontology pls powerful preventive rela representation shed signatures slide slides smurf1 squares srsf1 virtual www ywhae
Tagcloud (Intersection) ?