NMT1 and MARCKS

Number of citations of the paper that reports this interaction (PMID 10734119)
11

Data Source:
HPRD (in vitro)

		NMT1	MARCKS
Gene Name		N-myristoyltransferase 1	myristoylated alanine-rich protein kinase C substrate
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Actin Cytoskeleton Extrinsic Component Of Membrane Cell Junction	Centrosome Plasma Membrane Focal Adhesion Cell Cortex Actin Cytoskeleton Germinal Vesicle Extracellular Vesicular Exosome
	Molecular Function	Glycylpeptide N-tetradecanoyltransferase Activity	Protein Kinase C Binding Calmodulin Binding Actin Filament Binding
	Biological Process	In Utero Embryonic Development Apoptotic Process Phototransduction, Visible Light Viral Process Rhodopsin Mediated Signaling Pathway N-terminal Peptidyl-glycine N-myristoylation Regulation Of Rhodopsin Mediated Signaling Pathway Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway	Energy Reserve Metabolic Process Small Molecule Metabolic Process Regulation Of Insulin Secretion
Pathways		Inactivation, recovery and regulation of the phototransduction cascade HIV Life Cycle Visual phototransduction Activation, myristolyation of BID and translocation to mitochondria The phototransduction cascade HIV Infection Programmed Cell Death Diseases associated with visual transduction Late Phase of HIV Life Cycle Intrinsic Pathway for Apoptosis	Acetylcholine regulates insulin secretion Integration of energy metabolism Regulation of insulin secretion
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: ANXA13 ARL5A CABP1 CABP2 CAPN2 CSNK2A1 FYN GNAZ HPCA LYN MARCKS NOS3 SRC TP53	13 interactors: CALM2 CCNE1 CDK1 CDK2 CDK4 CTSB NMT1 PKN1 PRKCA PRKCB PRKCZ SPP1 TOB1
Entrez ID		4836	4082
HPRD ID		01187	07519
Ensembl ID		ENSG00000136448	ENSG00000155130
Uniprot IDs		P30419	P29966
PDB IDs		1RXT 3IU1 3IU2 3IWE 3JTK
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Localization Regulation Of Cellular Localization Regulation Of Establishment Of Protein Localization Peptidyl-tyrosine Autophosphorylation Negative Regulation Of Catalytic Activity Blood Coagulation Hemostasis Regulation Of Intracellular Transport T Cell Costimulation Regulation Of Body Fluid Levels Wound Healing Cellular Response To Platelet-derived Growth Factor Stimulus Response To Abiotic Stimulus Regulation Of Protein Transport Response To Platelet-derived Growth Factor Ephrin Receptor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Response To Wounding Intracellular Signal Transduction Regulation Of Cellular Component Organization Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Axon Guidance Negative Regulation Of Hydrolase Activity Cellular Response To Lipopolysaccharide Regulation Of Apoptotic Process Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc Receptor Mediated Stimulatory Signaling Pathway Fc-gamma Receptor Signaling Pathway Negative Regulation Of Protein Metabolic Process Cellular Response To Molecule Of Bacterial Origin Regulation Of Cell Proliferation Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Apoptotic Process Positive Regulation Of Phosphatidylinositol 3-kinase Activity Cellular Response To Organonitrogen Compound Negative Regulation Of Programmed Cell Death Regulation Of Protein Oligomerization Regulation Of Cell Activation Cellular Response To Acid Chemical Regulation Of Cell Death Positive Regulation Of Leukocyte Apoptotic Process Regulation Of Platelet Activation Response To Drug Negative Regulation Of Cell Death Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Calcium Ion Transport Platelet Activation Anatomical Structure Morphogenesis Axonogenesis Protein Autophosphorylation	Histone Phosphorylation Vascular Endothelial Growth Factor Receptor Signaling Pathway Peptidyl-threonine Phosphorylation Regulation Of Protein Kinase Activity Phosphorylation Regulation Of Kinase Activity Cellular Response To Stimulus Protein Phosphorylation Regulation Of Cellular Protein Metabolic Process Signal Transduction Regulation Of Protein Metabolic Process Histone H3-T6 Phosphorylation Regulation Of Rhodopsin Mediated Signaling Pathway Signaling Cell Communication Regulation Of Protein Phosphorylation Regulation Of Catalytic Activity Rhodopsin Mediated Signaling Pathway Mitotic Cell Cycle Process Response To Stress Mitotic Nuclear Envelope Disassembly Response To Wounding Positive Regulation Of Cellular Metabolic Process Chromatin Organization Response To Stimulus Negative Regulation Of Insulin Receptor Signaling Pathway G1/S Transition Of Mitotic Cell Cycle Intracellular Signal Transduction Mitotic Cell Cycle Histone Modification Nuclear Envelope Disassembly Positive Regulation Of Signal Transduction Regulation Of Phosphorylation Blood Coagulation Hemostasis Phosphate-containing Compound Metabolic Process Platelet Activation Regulation Of Insulin Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Phosphorus Metabolic Process Regulation Of Cell Cycle Response To Hormone Peptidyl-amino Acid Modification Nuclear Envelope Organization Positive Regulation Of Phospholipase Activity Cellular Protein Modification Process Cellular Protein Metabolic Process Regulation Of Cellular Response To Insulin Stimulus Chromosome Organization Mitotic Cell Cycle Phase Transition
Tagcloud ?		c2 cdc25p cys639 elongation fission g2 hect intensified lacks ligases overlaps owing polar pombe pub1 pub1delta pub1p pub2 pub2ca pub2p pub3p replaced rsp5 schizosaccharomyces shares starvation thiol ubiquitinated ww	approximate brainstem bulb ca1 ca3 callosum cerebellar corpus cortices declined entorhinal filamentous fimbria fornix granule habenula hilus medial mrp myristoylated neocortex olfactory p1 p14 p7 phosphoproteins purkinje thalamus thirds
Tagcloud (Difference) ?		c2 cdc25p cys639 elongation fission g2 hect intensified lacks ligases overlaps owing polar pombe pub1 pub1delta pub1p pub2 pub2ca pub2p pub3p replaced rsp5 schizosaccharomyces shares starvation thiol ubiquitinated ww	approximate brainstem bulb ca1 ca3 callosum cerebellar corpus cortices declined entorhinal filamentous fimbria fornix granule habenula hilus medial mrp myristoylated neocortex olfactory p1 p14 p7 phosphoproteins purkinje thalamus thirds
Tagcloud (Intersection) ?